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Personalizing esketamine treatment in TRD and TRBD

https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1736114
1•PaulHoule•1m ago•0 comments

SpaceKit.xyz – a browser‑native VM for decentralized compute

https://spacekit.xyz
1•astorrivera•1m ago•1 comments

NotebookLM: The AI that only learns from you

https://byandrev.dev/en/blog/what-is-notebooklm
1•byandrev•2m ago•1 comments

Show HN: An open-source starter kit for developing with Postgres and ClickHouse

https://github.com/ClickHouse/postgres-clickhouse-stack
1•saisrirampur•2m ago•0 comments

Game Boy Advance d-pad capacitor measurements

https://gekkio.fi/blog/2026/game-boy-advance-d-pad-capacitor-measurements/
1•todsacerdoti•2m ago•0 comments

South Korean crypto firm accidentally sends $44B in bitcoins to users

https://www.reuters.com/world/asia-pacific/crypto-firm-accidentally-sends-44-billion-bitcoins-use...
1•layer8•3m ago•0 comments

Apache Poison Fountain

https://gist.github.com/jwakely/a511a5cab5eb36d088ecd1659fcee1d5
1•atomic128•5m ago•1 comments

Web.whatsapp.com appears to be having issues syncing and sending messages

http://web.whatsapp.com
1•sabujp•6m ago•2 comments

Google in Your Terminal

https://gogcli.sh/
1•johlo•7m ago•0 comments

Shannon: Claude Code for Pen Testing: #1 on Github today

https://github.com/KeygraphHQ/shannon
1•hendler•7m ago•0 comments

Anthropic: Latest Claude model finds more than 500 vulnerabilities

https://www.scworld.com/news/anthropic-latest-claude-model-finds-more-than-500-vulnerabilities
2•Bender•12m ago•0 comments

Brooklyn cemetery plans human composting option, stirring interest and debate

https://www.cbsnews.com/newyork/news/brooklyn-green-wood-cemetery-human-composting/
1•geox•12m ago•0 comments

Why the 'Strivers' Are Right

https://greyenlightenment.com/2026/02/03/the-strivers-were-right-all-along/
1•paulpauper•13m ago•0 comments

Brain Dumps as a Literary Form

https://davegriffith.substack.com/p/brain-dumps-as-a-literary-form
1•gmays•14m ago•0 comments

Agentic Coding and the Problem of Oracles

https://epkconsulting.substack.com/p/agentic-coding-and-the-problem-of
1•qingsworkshop•14m ago•0 comments

Malicious packages for dYdX cryptocurrency exchange empties user wallets

https://arstechnica.com/security/2026/02/malicious-packages-for-dydx-cryptocurrency-exchange-empt...
1•Bender•14m ago•0 comments

Show HN: I built a <400ms latency voice agent that runs on a 4gb vram GTX 1650"

https://github.com/pheonix-delta/axiom-voice-agent
1•shubham-coder•15m ago•0 comments

Penisgate erupts at Olympics; scandal exposes risks of bulking your bulge

https://arstechnica.com/health/2026/02/penisgate-erupts-at-olympics-scandal-exposes-risks-of-bulk...
4•Bender•15m ago•0 comments

Arcan Explained: A browser for different webs

https://arcan-fe.com/2026/01/26/arcan-explained-a-browser-for-different-webs/
1•fanf2•17m ago•0 comments

What did we learn from the AI Village in 2025?

https://theaidigest.org/village/blog/what-we-learned-2025
1•mrkO99•17m ago•0 comments

An open replacement for the IBM 3174 Establishment Controller

https://github.com/lowobservable/oec
1•bri3d•20m ago•0 comments

The P in PGP isn't for pain: encrypting emails in the browser

https://ckardaris.github.io/blog/2026/02/07/encrypted-email.html
2•ckardaris•22m ago•0 comments

Show HN: Mirror Parliament where users vote on top of politicians and draft laws

https://github.com/fokdelafons/lustra
1•fokdelafons•23m ago•1 comments

Ask HN: Opus 4.6 ignoring instructions, how to use 4.5 in Claude Code instead?

1•Chance-Device•24m ago•0 comments

We Mourn Our Craft

https://nolanlawson.com/2026/02/07/we-mourn-our-craft/
1•ColinWright•27m ago•0 comments

Jim Fan calls pixels the ultimate motor controller

https://robotsandstartups.substack.com/p/humanoids-platform-urdf-kitchen-nvidias
1•robotlaunch•30m ago•0 comments

Exploring a Modern SMTPE 2110 Broadcast Truck with My Dad

https://www.jeffgeerling.com/blog/2026/exploring-a-modern-smpte-2110-broadcast-truck-with-my-dad/
1•HotGarbage•30m ago•0 comments

AI UX Playground: Real-world examples of AI interaction design

https://www.aiuxplayground.com/
1•javiercr•31m ago•0 comments

The Field Guide to Design Futures

https://designfutures.guide/
1•andyjohnson0•32m ago•0 comments

The Other Leverage in Software and AI

https://tomtunguz.com/the-other-leverage-in-software-and-ai/
1•gmays•34m ago•0 comments
Open in hackernews

The 90-Minute Flow Protocol: Using Neuroscience and Claude Code

4•IgorGanapolsky•6mo ago
After burning out twice in my career, I became obsessed with peak performance research. What I discovered changed everything: combining Steven Kotler's flow triggers with AI coding tools and the right hardware setup created a productivity multiplier I never thought possible.

Here's the protocol that took me from struggling with 3-hour focus sessions to crushing 8-hour deep work days:

## The Neuroscience Foundation

Steven Kotler's research at the Flow Research Collective shows that flow states can increase productivity by 500% (McKinsey study). The key? *90-120 minute uninterrupted blocks* aligned with your brain's natural ultradian rhythms.

But here's what most developers miss: flow requires three critical components working in harmony: 1. *Neurochemical optimization* (dopamine, norepinephrine, anandamide) 2. *Environmental design* (minimal friction, maximum feedback) 3. *Skill-challenge balance* (4% beyond current ability)

## My Tech Stack for Flow

### 1. Pre-Flow State Induction (20 minutes) - *Transcendental Meditation*: fMRI studies show TM increases blood flow to the anterior cingulate cortex (attention) while decreasing activity in the pons (arousal). This creates the "relaxed focus" ideal for coding. - *Clear Goals List*: Written the night before, ordered by difficulty/reward ratio

### 2. The Hardware Layer After testing 15+ keyboards, the *Kinesis Advantage2* became my secret weapon. Here's why: - *Contoured design*: Reduces finger travel by 40%, keeping you in flow longer - *Programmable layers*: I've mapped all brackets, braces, and common code patterns to thumb clusters - *Split design*: Maintains open chest posture, improving oxygen flow to the brain

Senior developers at FAANG companies swear by it for a reason.

### 3. The AI Amplification Layer

*Claude Code* in the terminal is the missing piece that makes flow states sustainable: - *Context-aware assistance*: Unlike IDE copilots, it understands your entire codebase structure - *Minimal context switching*: No GUI interruptions, pure terminal flow - *Intelligent error handling*: When you hit a snag, Claude debugs without breaking concentration

Combined with *Warp's Agent Mode*, I can describe complex refactors in natural language and watch them execute while maintaining flow.

### 4. The Automation Infrastructure

Using *n8n* for workflow automation eliminated the micro-interruptions that kill flow: - Auto-summarizes Slack threads and emails during focus blocks - Generates PR descriptions from commit history - Triggers *Neo4j* knowledge graphs to surface relevant code patterns from past projects

## The Results

Week 1: 2x productivity increase Week 4: Consistent 4-hour flow sessions Week 12: Shipping features that used to take weeks in days

The compound effect is real. When you combine: - Neurobiologically optimized work blocks - Ergonomic hardware that disappears - AI that amplifies rather than interrupts - Automation that handles the mundane

You don't just code faster. You code at a fundamentally different level.

## Start Small

1. Try one 90-minute block tomorrow morning 2. Use a timer, no exceptions 3. Clear goals, no multitasking 4. Invest in hardware that respects your biology

The future of development isn't about working harder. It's about working in harmony with how our brains actually function.

---

If you're curious about the Kinesis Advantage2, I've been using it for 2 years now and it's transformed my coding endurance: [Check it out on Amazon](https://www.amazon.com/dp/B01KR1C5PY?tag=igorganapolsk-20)

What's your flow protocol? Always looking to optimize further.