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Polymorphisms, gene expression, splicing in response to exercise and weight loss

https://www.sciencedirect.com/science/article/pii/S2666979X25002071
1•PaulHoule•2h ago

Developers, Reinvented

https://ashtom.github.io/developers-reinvented
1•lawgimenez•1m ago•0 comments

Tucson City Council Pulls Plug on Amazon's Project Blue Data Center

https://www.tucsonsentinel.com/local/report/080625_project_blue/tucson-city-council-pulls-plug-amazons-project-blue/
1•toomuchtodo•1m ago•1 comments

Data Science Weekly – Issue 611

https://datascienceweekly.substack.com/p/data-science-weekly-issue-611
1•sebg•5m ago•0 comments

GPT-5 for Vision: Results from 80 Real-World Tests

https://blog.roboflow.com/gpt-5-vision-multimodal-evaluation/
1•zerojames•10m ago•0 comments

The US Economy Was Supposed to Be in a Recession by Now. What Happened?

https://www.derekthompson.org/p/if-trumps-economic-ideas-are-so-terrible
1•gamechangr•12m ago•0 comments

Models CLI now auto-generates test cases and an evaluator

https://github.blog/changelog/2025-08-06-models-cli-now-auto-generates-test-cases-and-an-evaluator/
1•mooreds•14m ago•0 comments

Brazil movie: as prescient as ever, 40 years later

https://www.theverge.com/film/719308/brazil-movie-terry-gilliam-criterion-4k-restoration
5•janandonly•16m ago•0 comments

More Worlds, More Power: The Road to Greater Capacity

https://secure.runescape.com/m=news/more-worlds-more-power-the-road-to-greater-capacity?oldschool=1
1•devortel•17m ago•0 comments

Disposable Code Is Here to Stay, but Durable Code Is What Runs the World

https://www.honeycomb.io/blog/disposable-code-is-here-to-stay
2•Bogdanp•20m ago•1 comments

The Bull Market for Economists Is Over. It's an Ominous Sign for the Economy

https://www.nytimes.com/2025/07/28/business/economics-jobs-hiring.html
2•bookofjoe•21m ago•1 comments

Symbiont: An open-source agent runtime for building and governing autonomous AI

https://github.com/ThirdKeyAI/Symbiont
2•smugglereal•23m ago•0 comments

Remarkable News in Potatoes: They Evolved from Tomatoes

https://www.theatlantic.com/science/archive/2025/07/potato-tomato-evolution-hybrid/683721/
1•janandonly•23m ago•1 comments

We shipped GPT-5 support before lunch

https://www.assembled.com/blog/how-we-shipped-gpt-5-support-before-lunch
2•johnjwang•25m ago•0 comments

In trial, people lost twice as much weight by ditching ultraprocessed food

https://arstechnica.com/health/2025/08/in-trial-people-lost-twice-as-much-weight-by-ditching-ultraprocessed-food/
4•akyuu•28m ago•0 comments

Live jamming and personalization in Magenta RealTime open-weights music model

https://twitter.com/jesseengel/status/1953496623696556478
1•HxokcPwi•28m ago•1 comments

Show HN: 'Backed by YC' Embeddable Widget

https://yc-widget.pages.dev
2•TimCTRL•29m ago•0 comments

Mathematicians credited with rescuing quantum computing

https://today.usc.edu/mathematicians-use-neglected-particles-that-could-rescue-quantum-computing/
2•jonbaer•33m ago•0 comments

Doctor Strange: The curious life of Elon Musk's Canadian grandfather

https://torontolife.com/deep-dives/doctor-strange-the-curious-life-of-elon-musks-canadian-grandfather/
2•pseudolus•33m ago•1 comments

Learn Rust by Reasoning with Code Agents

https://xuanwo.io/2025/05-learn-rust-by-reasoning-with-code-agents/
2•sebg•33m ago•0 comments

The worlds most convoluted spirograph [video]

https://www.youtube.com/watch?v=tuC0qnyPrvM
2•sebg•33m ago•0 comments

Why I'm Joining Substack

https://www.derekthompson.org/p/why-im-joining-substack
2•gamechangr•36m ago•0 comments

How to Ask Questions the Smart Way

http://www.catb.org/~esr/faqs/smart-questions.html
3•mhb•37m ago•0 comments

Improving Oversight of Federal Grantmaking

https://www.whitehouse.gov/presidential-actions/2025/08/improving-oversight-of-federal-grantmaking/
2•petethomas•39m ago•0 comments

Every Game is the Same Game [video]

https://www.youtube.com/watch?v=26HyHFTtPpM
2•ivanjermakov•39m ago•0 comments

Is AI ruining music? [video]

https://www.ted.com/talks/dustin_ballard_is_ai_ruining_music
1•jedberg•41m ago•0 comments

If GLP-1 Drugs Are Good for Everything, Should We All Be on Them?

https://www.derekthompson.org/p/why-does-it-seem-like-glp-1-drugs
12•gamechangr•41m ago•4 comments

Vibechart

https://www.vibechart.net/
66•datadrivenangel•41m ago•9 comments

NYT: Staggering U.S. Tariffs Begin as Trump Widens Trade War

https://www.nytimes.com/2025/08/07/business/economy/trump-tariffs-trade-war.html
2•Animats•43m ago•0 comments

Alberta no longer sure about big savings from auto insurance reforms

https://www.cbc.ca/news/canada/calgary/alberta-insurance-savings-400-doubtful-analysis-1.7603277
8•geox•44m ago•0 comments

Shell-with-me/shwim: instant E2EE terminal sharing

https://meejah.ca/blog/initial-shwim-release
1•meejah•48m ago•1 comments