Can anyone explain why the vaccine for TB works to treat bladder cancer?
If half of people get rid of cancer for 1 year that is still outstanding - ESPECIALLY if the majority of those remain cancer free for quite some time after.
The US is literally crushing both innovation and talent at the same time. Think of all the brilliant minds who can’t—or won’t bother—coming here to test their ideas because visas are paused, revoked, or delayed for political reasons. Worse, proposed H-1B changes favoring only high-wage workers could shut out fresh grads entirely. At this rate, funding is being starved for political concessions, and the next generation of genius scientists might be too scared—or flat-out blocked—from studying and innovating here.
And it’s not just foreign students—even native US students are looking at science careers that might not exist in a few years. My wife is an accountant for research grants, and ALL her PIs are still in a daze, trying to process what’s happening.
Again… depressing AF. THe US based science/research pipeline is toast.
repeating the same karma-farming copy isn't even mid at this point
try reddit
We are breaking the innovation machine and pretending discoveries will just keep happening.
In fact, some other developed nations do it in far greater percentages of the universities' independent revenue.
Many also have quite comparatively easy immigration paths for both students and workers.
I do think a lot of grant funding will cycle back around. There's every reason for commercial sourcing to become a larger portion of university funding as well as university funding directly from endowments considering the profit motivations in both cases. I think it's far from dead, just changing.
2) Very few schools have endowments that are large enough to support current faculty research costs; even Harvard can only support all research off their endowment for about a year.
3) Endowments are now taxed, so they will have even less available for research.
If you think they will suddenly have a change of heart and start funding scientific discovery not just indirectly, but directly, then I have a bridge to sell you.
> https://www.sciencedirect.com/science/article/pii/S107814392...
> ...for individuals with high-risk non-muscle-invasive bladder cancer whose cancer had previously resisted treatment
newfocogi•1h ago
- "TAR-200 is a miniature, pretzel-shaped drug-device duo containing a chemotherapy drug, gemcitabine, which is inserted into the bladder through a catheter. Once inside the bladder, the TAR-200 slowly and consistently releases the gemcitabine into the organ for three weeks per treatment cycle."
- Phase 2 Clinical Trial
- 85 patients with high-risk non-muscle-invasive bladder cancer
- "treated patients with TAR-200 every three weeks for six months, and then four times a year for the next two years"
- 70/85 patients—the cancer disappeared and still gone 1yr later in almost 50% patients
- FDA granted TAR-200 a New Drug Application Priority Review
- Johnson & Johnson manufactures TAR-200
woeirua•44m ago
tptacek•33m ago
lordofgibbons•9m ago