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The next frontier in weight-loss drugs: one-time gene therapy

https://www.washingtonpost.com/health/2026/01/24/fractyl-glp1-gene-therapy/
1•bookofjoe•1m ago•1 comments

At Age 25, Wikipedia Refuses to Evolve

https://spectrum.ieee.org/wikipedia-at-25
1•asdefghyk•3m ago•2 comments

Show HN: ReviewReact – AI review responses inside Google Maps ($19/mo)

https://reviewreact.com
1•sara_builds•4m ago•0 comments

Why AlphaTensor Failed at 3x3 Matrix Multiplication: The Anchor Barrier

https://zenodo.org/records/18514533
1•DarenWatson•5m ago•0 comments

Ask HN: How much of your token use is fixing the bugs Claude Code causes?

1•laurex•8m ago•0 comments

Show HN: Agents – Sync MCP Configs Across Claude, Cursor, Codex Automatically

https://github.com/amtiYo/agents
1•amtiyo•9m ago•0 comments

Hello

1•otrebladih•11m ago•0 comments

FSD helped save my father's life during a heart attack

https://twitter.com/JJackBrandt/status/2019852423980875794
2•blacktulip•13m ago•0 comments

Show HN: Writtte – Draft and publish articles without reformatting, anywhere

https://writtte.xyz
1•lasgawe•15m ago•0 comments

Portuguese icon (FROM A CAN) makes a simple meal (Canned Fish Files) [video]

https://www.youtube.com/watch?v=e9FUdOfp8ME
1•zeristor•17m ago•0 comments

Brookhaven Lab's RHIC Concludes 25-Year Run with Final Collisions

https://www.hpcwire.com/off-the-wire/brookhaven-labs-rhic-concludes-25-year-run-with-final-collis...
2•gnufx•19m ago•0 comments

Transcribe your aunts post cards with Gemini 3 Pro

https://leserli.ch/ocr/
1•nielstron•23m ago•0 comments

.72% Variance Lance

1•mav5431•24m ago•0 comments

ReKindle – web-based operating system designed specifically for E-ink devices

https://rekindle.ink
1•JSLegendDev•26m ago•0 comments

Encrypt It

https://encryptitalready.org/
1•u1hcw9nx•26m ago•1 comments

NextMatch – 5-minute video speed dating to reduce ghosting

https://nextmatchdating.netlify.app/
1•Halinani8•27m ago•1 comments

Personalizing esketamine treatment in TRD and TRBD

https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1736114
1•PaulHoule•28m ago•0 comments

SpaceKit.xyz – a browser‑native VM for decentralized compute

https://spacekit.xyz
1•astorrivera•29m ago•0 comments

NotebookLM: The AI that only learns from you

https://byandrev.dev/en/blog/what-is-notebooklm
2•byandrev•29m ago•1 comments

Show HN: An open-source starter kit for developing with Postgres and ClickHouse

https://github.com/ClickHouse/postgres-clickhouse-stack
1•saisrirampur•30m ago•0 comments

Game Boy Advance d-pad capacitor measurements

https://gekkio.fi/blog/2026/game-boy-advance-d-pad-capacitor-measurements/
1•todsacerdoti•30m ago•0 comments

South Korean crypto firm accidentally sends $44B in bitcoins to users

https://www.reuters.com/world/asia-pacific/crypto-firm-accidentally-sends-44-billion-bitcoins-use...
2•layer8•31m ago•0 comments

Apache Poison Fountain

https://gist.github.com/jwakely/a511a5cab5eb36d088ecd1659fcee1d5
1•atomic128•33m ago•2 comments

Web.whatsapp.com appears to be having issues syncing and sending messages

http://web.whatsapp.com
1•sabujp•33m ago•2 comments

Google in Your Terminal

https://gogcli.sh/
1•johlo•34m ago•0 comments

Shannon: Claude Code for Pen Testing: #1 on Github today

https://github.com/KeygraphHQ/shannon
1•hendler•35m ago•0 comments

Anthropic: Latest Claude model finds more than 500 vulnerabilities

https://www.scworld.com/news/anthropic-latest-claude-model-finds-more-than-500-vulnerabilities
2•Bender•39m ago•0 comments

Brooklyn cemetery plans human composting option, stirring interest and debate

https://www.cbsnews.com/newyork/news/brooklyn-green-wood-cemetery-human-composting/
1•geox•39m ago•0 comments

Why the 'Strivers' Are Right

https://greyenlightenment.com/2026/02/03/the-strivers-were-right-all-along/
1•paulpauper•41m ago•0 comments

Brain Dumps as a Literary Form

https://davegriffith.substack.com/p/brain-dumps-as-a-literary-form
1•gmays•41m ago•0 comments
Open in hackernews

Show HN: Knowledgework – AI Extensions of Your Coworkers

https://knowledgework.ai/
8•grbsh•5mo ago
Hey HN! We’re building Knowledgework.ai, which creates AI clones of your coworkers that actually know what they know. It's like having a version of each teammate that never sleeps, never judges you for asking "dumb" questions, and responds instantly.

As a SWE at Amazon, I constantly faced two frustrations:

1. Getting interrupted on Slack all day with questions I'd already answered

2. Waiting hours (or days) for responses when I needed information from teammates

When you compare this to the UX of an AI chatbot, humans start to look pretty inconvenient! It’s a bit of a wild take, but it’s really been reflected in my conversations with dozens of engineers, and especially juniors: people would rather spend 20 minutes wrestling with an unreliable AI than risk looking ignorant or wasting their coworkers’ time. One of my early users actually tried the product and told me she’s a bit worried her coworkers would prefer talking to her AI extension over talking to her!

Here’s how it works: It’s a desktop app (mac only right now) that captures screenshots every 5 seconds while you work. It uses a bespoke, ultra-long context vision model (OCR isn’t enough, and generic models are far too expensive!) to understand what you're doing and automatically builds a searchable, hyperlinked knowledge base (wiki) of everything you work on - code you write, bugs you fix, decisions you make, or anything else you do on a computer that could be useful to you or your team’s productivity in the future.

Even if you just turn on Knowledgework for ~30 mins while working on a personal project, I think you’ll find what it produces to be really interesting — something I’ve learned is that we tend to underestimate the extent of the valuable information we produce every day that is just ephemeral and forgotten. There’s also some really great opportunities surrounding quantified self and reflection — just ask it how you could have been more productive yesterday or how you could come across better in your meetings.

The real value comes when your teammates can query your "Extension" - an AI agent that has access to all (only what you choose to share) of your captured work context. Imagine your coworker is on vacation, but you can still ask their Extension: "I'm trying to deploy a new Celery worker. It's gossiping but not receiving tasks. Have you seen this before?"

We’ve spent a great deal of effort on optimizing for privacy as a priority; not just in terms of encryption and data security, but in terms of modulating what your Extension will divulge in a relationship appropriate way, and how you can configure this. By default, nothing is shared. In a team setting, you can choose to share your Extension with particular individuals. You can, in a fine-grained manner, grant and revoke access to portions of your time, or if you are on a tight-knit team, you can just leave it to AI to decide what makes sense to be accessed. This is the area we’re most excited to get feedback on, so we’re really aiming this launch at small, tight knit teams who care about speed and productivity at all costs who use Macs, Slack, Notion, and are all on Claude Code Max plans.

We’re also working on SOC II type 2 compliance and can do on-prem, although on-prem will be quite expensive. If you’re curious about on-prem or additional certifications, I’d love to chat - griffin@knowledgework.ai.

Check it out here: https://knowledgework.ai/

We’ve opened it up today for anyone to install and use for free. If you’re seeing this after Thursday 8/28, we’ll likely have put back the code wall — but we’d be happy to give codes to anyone who reaches out to griffin@knowledgework.ai

Comments

redhale•5mo ago
Honest feedback: I am usually not someone obsessed with privacy. I use Google services for a lot of things, I accept most cookies, I don't use local models, etc.

But when I read "captures screenshots every 5 seconds while you work" I nope'd out harder than I have for any product in recent memory. No thank you. I'll deal with the interruptions from coworkers for now. Surely there must be a better solution than this.

e-clinton•5mo ago
What you’re doing is coming…Microsoft is already working on this problem—the issue is trust. I only see this working as an open source initiative where people can inspect the code, run their own servers and provide their own keys. Maybe do open core in which you upsell certain reports or other features.