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Brute Force Colors (2022)

https://arnaud-carre.github.io/2022-12-30-amiga-ham/
1•erickhill•34s ago•0 comments

Google Translate apparently vulnerable to prompt injection

https://www.lesswrong.com/posts/tAh2keDNEEHMXvLvz/prompt-injection-in-google-translate-reveals-ba...
1•julkali•43s ago•0 comments

(Bsky thread) "This turns the maintainer into an unwitting vibe coder"

https://bsky.app/profile/fullmoon.id/post/3meadfaulhk2s
1•todsacerdoti•1m ago•0 comments

Software development is undergoing a Renaissance in front of our eyes

https://twitter.com/gdb/status/2019566641491963946
1•tosh•1m ago•0 comments

Can you beat ensloppification? I made a quiz for Wikipedia's Signs of AI Writing

https://tryward.app/aiquiz
1•bennydog224•3m ago•1 comments

Spec-Driven Design with Kiro: Lessons from Seddle

https://medium.com/@dustin_44710/spec-driven-design-with-kiro-lessons-from-seddle-9320ef18a61f
1•nslog•3m ago•0 comments

Agents need good developer experience too

https://modal.com/blog/agents-devex
1•birdculture•4m ago•0 comments

The Dark Factory

https://twitter.com/i/status/2020161285376082326
1•Ozzie_osman•4m ago•0 comments

Free data transfer out to internet when moving out of AWS (2024)

https://aws.amazon.com/blogs/aws/free-data-transfer-out-to-internet-when-moving-out-of-aws/
1•tosh•5m ago•0 comments

Interop 2025: A Year of Convergence

https://webkit.org/blog/17808/interop-2025-review/
1•alwillis•6m ago•0 comments

Prejudice Against Leprosy

https://text.npr.org/g-s1-108321
1•hi41•7m ago•0 comments

Slint: Cross Platform UI Library

https://slint.dev/
1•Palmik•11m ago•0 comments

AI and Education: Generative AI and the Future of Critical Thinking

https://www.youtube.com/watch?v=k7PvscqGD24
1•nyc111•11m ago•0 comments

Maple Mono: Smooth your coding flow

https://font.subf.dev/en/
1•signa11•12m ago•0 comments

Moltbook isn't real but it can still hurt you

https://12gramsofcarbon.com/p/tech-things-moltbook-isnt-real-but
1•theahura•16m ago•0 comments

Take Back the Em Dash–and Your Voice

https://spin.atomicobject.com/take-back-em-dash/
1•ingve•17m ago•0 comments

Show HN: 289x speedup over MLP using Spectral Graphs

https://zenodo.org/login/?next=%2Fme%2Fuploads%3Fq%3D%26f%3Dshared_with_me%25253Afalse%26l%3Dlist...
1•andrespi•18m ago•0 comments

Teaching Mathematics

https://www.karlin.mff.cuni.cz/~spurny/doc/articles/arnold.htm
2•samuel246•20m ago•0 comments

3D Printed Microfluidic Multiplexing [video]

https://www.youtube.com/watch?v=VZ2ZcOzLnGg
2•downboots•20m ago•0 comments

Abstractions Are in the Eye of the Beholder

https://software.rajivprab.com/2019/08/29/abstractions-are-in-the-eye-of-the-beholder/
2•whack•21m ago•0 comments

Show HN: Routed Attention – 75-99% savings by routing between O(N) and O(N²)

https://zenodo.org/records/18518956
1•MikeBee•21m ago•0 comments

We didn't ask for this internet – Ezra Klein show [video]

https://www.youtube.com/shorts/ve02F0gyfjY
1•softwaredoug•22m ago•0 comments

The Real AI Talent War Is for Plumbers and Electricians

https://www.wired.com/story/why-there-arent-enough-electricians-and-plumbers-to-build-ai-data-cen...
2•geox•24m ago•0 comments

Show HN: MimiClaw, OpenClaw(Clawdbot)on $5 Chips

https://github.com/memovai/mimiclaw
1•ssslvky1•25m ago•0 comments

I Maintain My Blog in the Age of Agents

https://www.jerpint.io/blog/2026-02-07-how-i-maintain-my-blog-in-the-age-of-agents/
3•jerpint•25m ago•0 comments

The Fall of the Nerds

https://www.noahpinion.blog/p/the-fall-of-the-nerds
1•otoolep•27m ago•0 comments

Show HN: I'm 15 and built a free tool for reading ancient texts.

https://the-lexicon-project.netlify.app/
3•breadwithjam•30m ago•1 comments

How close is AI to taking my job?

https://epoch.ai/gradient-updates/how-close-is-ai-to-taking-my-job
1•cjbarber•30m ago•0 comments

You are the reason I am not reviewing this PR

https://github.com/NixOS/nixpkgs/pull/479442
2•midzer•32m ago•1 comments

Show HN: FamilyMemories.video – Turn static old photos into 5s AI videos

https://familymemories.video
1•tareq_•33m ago•0 comments
Open in hackernews

A history of metaphorical brain talk in psychiatry

https://www.nature.com/articles/s41380-025-03053-6
41•fremden•5mo ago

Comments

unyttigfjelltol•5mo ago
> we have had little insight into exactly how disturbances in the brain cause psychiatric disorders

I recently heard a well-regarded neuropsychiatrist disavow any pretense of connecting his evaluation to the actual organic function of the brain or body. This was surprising for a—as far as I know— organic-focused subspecialty of a branch of medicine that routinely prescribes pharmaceuticals to achieve organic changes in the brain and body.

temp0826•5mo ago
I mean I sort of get it. When you aren't taking objective data (I don't know what that would even be, brain scans or testing for levels of neurotransmitters, if those levels even mean anything..?) then what can you do besides acknowledge that it's a black box? Guessing what is going on in someone's skull would be disingenuous, no?
tim333•5mo ago
I'm sure they would like to know what was going on in the brain but I think often people just don't. Probably the more scientifically sophisticated the person is, the more likely they are to admit that.

A lot of prescribing of psychiatric drugs seems to be trial and error as much as anything.

IFC_LLC•5mo ago
I have completed an interview with a neurosurgeon recently. I'm writing an article for a big magazine about AI and Brains, and I was given a chance to get some comments from a neurosurgeon about AI, thinkingness and how he things things work.

I can't disclose the contents of the interview, this is under NDA till published. But, gosh, was that bad.

I thought neurosurgeon would know something about thinking process, and stuff like that. The guy in a state of a total despair. When I was bashing him with questions about the purpose of a brain and all that stuff, he was almost crying.

He ended up telling me that he hopes that someone will find quantum entanglement in the brain, and everything will be fine after that. After he sent me to this from PBS Science.

https://www.youtube.com/watch?v=xa2Kpkksf3k

unyttigfjelltol•5mo ago
Thinking is slippery as a concept, but feelings are what they’re usually after, and these can be remarkably deterministic by other than mental processes. The study of Israeli judges was debunked, but I think we all have experienced this at some level.

The NPR show This American Life had a segment years ago on the mind, “Life is a Coin with One Side.”[1] Producer David Kestenbaum provided his take, including that quantum effects can inject randomness but do not provide a complete explanation for thinking process or free will. He recounted the story of a friend who engaged in repetitive behaviors after a concussion, as an illustration that the mind is a machine, which like AI has wonderful emergent capabilities.

[1] https://www.thisamericanlife.org/662/where-there-is-a-will/a...

tim333•5mo ago
Ha. I think it's unlikely to involve entanglement myself and probably the closest model we have at the moment is LLMs but obviously those are different. I think a lot of what neurosurgeons do is things like removing tumors and dealing with burst or clogged blood vessels which don't require understanding how the actual thinking works.
AIPedant•5mo ago
Keep in mind that we also have no clue how general anesthesia works! It's not just psychiatry, many medications targeting the nervous system (e.g. muscle relaxants) have unknown mechanisms of action https://en.wikipedia.org/wiki/Category:Drugs_with_unknown_me...

I think you're being extremely reductive about what neuropsychiatry actually entails.

gregfjohnson•5mo ago
I heard an interesting talk recently by a Stanford neuroscientist.

He was studying standing waves of brain activity among circularly linked groups of neurons. Neurons can provide both excitatory inputs and inhibitory inputs to other neurons.

For a computer programmer, it is easy to imagine excitatory and inhibitory localized phenomena giving rise to all sorts of interesting and complex self-sustaining standing waves.

Think of the study of cellular automata by Stephen Wolfram and others, in which various simple localized rules give rise to all sorts of interesting computational phenomena, up to and including Turing Completeness.

In animal models such as pigs, these standing waves can be observed to persist for months if not longer.

His particular area of interest is to subject the brain to gentle sub-lethal doses of radiation treatment in order to change selected standing waves.

My thought is that there may be a qualitative difference between the underlying "neural hardware" and the thought processes that "execute" on this hardware.

It is the bread and butter of computer scientists to reason in a world in which the complexity of software greatly exceeds the simple computational artifacts on which it runs.

One might say that chess has information content that is qualitatively dissimilar to the wood-working needed to make a pretty chess board.

The information content in DNA is composed of chemically interchangeable A, G, T, and C molecules. So, one might say that the underlying physics is "walled off" from the information content of the DNA. Evolution has, as it were, a free hand to encode advantageous alleles, with no bias introduced by the underlying physics or chemistry.

All this is to say "Hear hear!" to this excellent article.

The "metaphorical brain talk" the author describes may indeed be a conceptual limitation if applied too broadly to the mind.

tim333•5mo ago
I'm not really up on neuroscientific research but I'd think a way of progressing might be to make computer simulations of neurons and then see if you can get those to exhibit similar phenomena as those waves and other experimental observations.
o_nate•5mo ago
It would be interesting to explore further why this topic is still so sensitive for a lot of people, and why the metaphorical talk is still so appealing. I feel like the reasons given in this article couldn't alone explain its enormous staying power (even to this day).