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Selective packaging of RNA molecules by viral coat proteins in cells

https://www.pnas.org/doi/10.1073/pnas.2505190122
3•PaulHoule•4h ago

Comments

aurizon•3h ago
Interesting parallel with computer malware = LOTL where the attacking computer virus uses the embedded code used by the OS as picked up local attack tools. In a cell, time and adaptive advantage would cause competition between the host proteins and the viral coat proteins for whatever cellular task. If the viral ones are better = cell health uses them preferentially, but has the host protein as a less efficient fall back. It would thus tend to want to stay infected with the virus, while the immune system wants it cleared? Would this result in a need for the virus or would the cell grab patterns it wants to prosper with? Of course, we have deep time to contend with. Harkening to the roots of CRISPR as a bacterial immune system where things are tagged to be rejected - is there a similar system where patterns can be marked to prosper?

Native Multiplatforming – Android and Web

https://github.com/quaadgras/graphics.gd/discussions/177
1•Splizard•58s ago•0 comments

David Deutsch on AGI, the future of humanity, and more [video]

https://www.youtube.com/watch?v=IVA2bK9qjzE
1•ksdk•1m ago•0 comments

Repeated heatwaves can age you as much as smoking or drinking

https://www.nature.com/articles/d41586-025-02729-x
1•XzetaU8•2m ago•0 comments

AI Bubble –> AI Winter

https://en.wikipedia.org/wiki/AI_winter
1•baalimago•4m ago•0 comments

Using MacBook sensor API to make screen hinge sound like old wooden door

https://twitter.com/samhenrigold/status/1964428927159382261
1•adityaathalye•18m ago•1 comments

Need help with FAANG-o-meter

https://sagastar.com?redeem_invite=beta100
1•kind-serge•20m ago•0 comments

When Australian scientists almost brought back the extinct gastric brooding frog

https://www.abc.net.au/news/science/2025-09-06/gastric-brooding-frog-project-lazarus-deextinction...
1•stubish•23m ago•0 comments

How Much of Indian Medicine Is Bad?

https://sayacare.in/blogs/how-much-of-indian-medicines-is-bad
1•himanshu7net•23m ago•0 comments

Longhorn – A Kubernetes-Native Filesystem

https://vegard.blog.engen.priv.no/?p=518
3•jandeboevrie•24m ago•0 comments

Aspected Orinted Programming and Structured Logging

1•JasmineAs•25m ago•0 comments

Nvidia-backed U.S. atomic fusion firm eyes reactor in Japan

https://www.japantimes.co.jp/business/2025/09/04/companies/us-nuclear-fusion-firm-eyes-japan-reac...
1•breve•28m ago•0 comments

Platypuses glow under UV light and we have no idea why (2020)

https://www.nytimes.com/2020/11/13/science/platypus-glow-ultraviolet.html
1•spectraldrift•31m ago•0 comments

Building Towards AGI

https://poolside.ai/vision/research
2•matesz•31m ago•0 comments

The "impossibly small" Microdot web framework

https://lwn.net/Articles/1034121/
1•pykello•35m ago•0 comments

The Garden Speaks: On Cucumbers, Mildew, and Projects

https://zakelfassi.com/blog/2025/2025-09-06-garden-speaks-cucumbers-mildew-projects
1•zakelfassi•36m ago•0 comments

Wix

2•dadin•37m ago•0 comments

Patterns, PREDICTIONS, AND ACTIONS A story about machine learning [pdf]

https://mlstory.org/pdf/patterns.pdf
1•tzury•43m ago•0 comments

Facing stiff competition, remote workers up their game

https://apnews.com/article/finding-remote-jobs-employment-tips-76a61cc6a646493dc3f5e0bfa733160c
1•petethomas•43m ago•0 comments

Forget love triangles. Meet the 'polycule' with 80 people in it

https://www.thetimes.com/life-style/sex-relationships/article/polyamory-polycule-somerville-capit...
1•kensai•43m ago•0 comments

Magnetic Bubble Memory

https://www.smbaker.com/magnetic-bubble-memory-mega-post
2•dmitrygr•45m ago•0 comments

Performant girl and performative male in SF

1•ThatDumbGirl•49m ago•0 comments

What the Next 5 to 10 Years Look Like – Prof. Jiang Xueqin [video]

https://www.youtube.com/watch?v=_4HYxYF4998
1•hkhn•55m ago•1 comments

Liberalism Without Illusions

https://democracyjournal.org/magazine/77/liberalism-without-illusions/
1•hkhn•55m ago•0 comments

Resources, Laziness, and Continuation-Passing Style

https://journal.infinitenegativeutility.com/resources-laziness-and-continuation-passing-style
2•Bogdanp•57m ago•0 comments

Elizabeth Gilbert on Distinguishing Between Hobbies, Jobs, Careers, & Vocation [video]

https://www.youtube.com/watch?v=0g7ARarFNnw
1•adityaathalye•59m ago•0 comments

MVC: Xerox PARC 1978-79 – Trygve Reenskaug

https://folk.universitetetioslo.no/trygver/themes/mvc/mvc-index.html
1•lioeters•1h ago•0 comments

The Lunar Cowboy: Introducing unittest-fixtures

https://lunarcowboy.com/introducing-unittest-fixtures.html
1•PaulHoule•1h ago•0 comments

Postal traffic to U.S. fell 80% after gov stopped exemption on low-value parcels

https://www.cbsnews.com/news/postal-traffic-us-fell-trump-administration-stopped-exemption-low-va...
1•mraniki•1h ago•1 comments

Show HN: CRoM – Context Rot Mitigation System for RAG-Based LLMs

https://github.com/Flamehaven/CRoM-Context-Rot-Mitigation--EfficientLLM
1•Flamehaven01•1h ago•0 comments

Dream: Visual Decoding from Reversing Human Visual System

https://github.com/weihaox/DREAM
1•felipelalli•1h ago•0 comments