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The Glymphatic System

https://www.medscape.com/viewarticle/glymphatic-system-not-typo-brains-lymphatic-system-2025a1000nh1
3•wjb3•2h ago

Comments

ggm•2h ago
Measuring beta amyloid flow rates with a radioactive marker is very good. That's interesting science even if the whole causative/associated thing still runs, the body clearly processes amyloid differently across sleep and wake times.
DaveZale•1h ago
yes. When big pharma dropped 10+ billion on antibodies to amyloid, the results were not good due to excess deaths. But good sleep may be the best drug of all for clearance.

And how does one get reliably good sleep, sans medication? Exercise. Which might also help the clearance systems. How couldn't it? All that physical jostling can't hurt. It's a win-win

ggm•1h ago
Gotta be a lot of money flowing to apple, Samsung and garmin who have to spend to get FDA approval and then a revenue stream, into the future. Pharma should invest in technology and lay off some of the risks in shifting health spend.

Rust compiler performance survey 2025 results

https://blog.rust-lang.org/2025/09/10/rust-compiler-performance-survey-2025-results/
1•Bogdanp•1m ago•0 comments

Heliolens

https://heliolens.builtbyvibes.com/
1•watkajtys•5m ago•0 comments

My (speculative) master plan for immortality

https://maxwellnye.com/plan/
1•jxmorris12•11m ago•0 comments

ESP32-based boundary wire signal generator for Robomow RX/RT mowers

https://github.com/eelcogg/robomow-signal-generator
1•MBCook•11m ago•0 comments

Massively Parallel Agentic Simulations with Ray

https://www.anyscale.com/blog/massively-parallel-agentic-simulations-with-ray
2•robertnishihara•14m ago•0 comments

Anton Flettner

https://en.wikipedia.org/wiki/Anton_Flettner
1•domofutu•14m ago•0 comments

Sodium Ion Battery Tech Hits the Auto Industry – Are We Ready? [video]

https://www.youtube.com/watch?v=hqb7YtR7K4g
1•sixplusone•15m ago•1 comments

'Ghost Ship' Sails

https://www.popsci.com/technology/green-shipping-rotor-sails-history/
1•wjb3•16m ago•1 comments

Mosquitos seem to like beer drinkers who recently had sex

https://www.popsci.com/environment/mosquito-beer-blood/
2•wjb3•19m ago•1 comments

My EV roadtrip experience after upgrading from Chevy Bolt to Ioniq 6

https://thelifeelectric.us/a-new-car
1•nharada•27m ago•0 comments

Height limits raise housing prices

https://hardlyworking1.substack.com/p/zoning-height-caps-make-housing-more
2•paulpauper•27m ago•0 comments

Open Source Health: A Universal Device from Brain Stimulation to Cancer Therapy

https://docs.google.com/document/d/1fiOk9sKIvskWd-zkafJ7A_SZ9aazUIW2Oirse9jstmA/edit?usp=drivesdk
1•chrisweekly•31m ago•1 comments

Huginn and Muninn

https://en.wikipedia.org/wiki/Huginn_and_Muninn
2•wjb3•32m ago•1 comments

Polymorphic symmetric multiple dispatch with variance

https://dl.acm.org/doi/10.1145/3290324
4•andsoitis•37m ago•0 comments

Htmx (HTTPS://htmx.org) Snippets for Zed Code editor (HTTPS://zed.dev)

https://github.com/mfabing/zed-htmx-snippets
2•novusteck•37m ago•0 comments

The Four Fallacies of Modern AI

https://blog.apiad.net/p/the-four-fallacies-of-modern-ai
2•13years•43m ago•0 comments

Physically-Based Shading at Disney, by Brent Burley (2012) [pdf]

https://media.disneyanimation.com/uploads/production/publication_asset/48/asset/s2012_pbs_disney_...
1•xeonmc•46m ago•0 comments

User Engagement Bots used to kickstart conversations on Discourse forums

https://meta.discourse.org/t/user-engagement-bots/382265
1•EGreg•47m ago•2 comments

Preventing the NPM Debug/Chalk Compromise in 200 lines of JavaScript

https://getvouchsafe.org/blog/2025-09-10.html
2•jk0ne•55m ago•0 comments

First-class merges and cover letters

https://dotat.at/@/2025-09-11-cover-letter.html
1•chmaynard•56m ago•0 comments

Target Market Isn't Demographic

https://longform.asmartbear.com/target-market/
2•doppp•1h ago•0 comments

Apple paying $95M in a Siri eavesdropping settlement. How to file a claim

https://www.cbsnews.com/news/apple-siri-settlement-95-million-lopez-how-to-file-claim/
6•1vuio0pswjnm7•1h ago•0 comments

AI as Teleportation

https://www.geoffreylitt.com/2025/09/10/ai-as-teleportation.html
4•zdw•1h ago•2 comments

Show HN: Free AI website to test which hairstyle suits you

https://righthair.ai/
2•Pratte_Haza•1h ago•0 comments

Seoul says US must fix its visa system if it wants Korea's investments

https://english.hani.co.kr/arti/english_edition/e_international/1218025.html
87•garbawarb•1h ago•20 comments

Why Todays Identity and Access Management Can't Survive the AI Age

https://www.identityfusion.com/blog/the-death-of-the-old-guard-why-todays-iam-cant-survive-the-ai...
3•zerolayers•1h ago•0 comments

How 'BMX in a wheelchair' became an online sensation

https://www.bbc.com/sport/articles/cvg3px16zlmo
2•breve•1h ago•0 comments

Show HN: Pokémon Websites Top Resources for Fans and Collectors

https://www.pokemonguide.org/
1•yangyiming•1h ago•0 comments

From Unit Tests to Whole Universe Tests (With Will Wilson) [video]

https://www.youtube.com/watch?v=_xJ4maWhSNU
1•jrmurray•1h ago•0 comments

From Unit Tests to Whole Universe Tests (With Will Wilson)

https://www.youtube.com/watch?v=_xJ4maWhSNU
1•todsacerdoti•1h ago•0 comments