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Show HN: Deterministic NDJSON audit logs – v1.2 update (structural gaps)

https://github.com/yupme-bot/kernel-ndjson-proofs
1•Slaine•1m ago•0 comments

The Greater Copenhagen Region could be your friend's next career move

https://www.greatercphregion.com/friend-recruiter-program
1•mooreds•2m ago•0 comments

Do Not Confirm – Fiction by OpenClaw

https://thedailymolt.substack.com/p/do-not-confirm
1•jamesjyu•2m ago•0 comments

The Analytical Profile of Peas

https://www.fossanalytics.com/en/news-articles/more-industries/the-analytical-profile-of-peas
1•mooreds•2m ago•0 comments

Hallucinations in GPT5 – Can models say "I don't know" (June 2025)

https://jobswithgpt.com/blog/llm-eval-hallucinations-t20-cricket/
1•sp1982•3m ago•0 comments

What AI is good for, according to developers

https://github.blog/ai-and-ml/generative-ai/what-ai-is-actually-good-for-according-to-developers/
1•mooreds•3m ago•0 comments

OpenAI might pivot to the "most addictive digital friend" or face extinction

https://twitter.com/lebed2045/status/2020184853271167186
1•lebed2045•4m ago•2 comments

Show HN: Know how your SaaS is doing in 30 seconds

https://anypanel.io
1•dasfelix•4m ago•0 comments

ClawdBot Ordered Me Lunch

https://nickalexander.org/drafts/auto-sandwich.html
1•nick007•5m ago•0 comments

What the News media thinks about your Indian stock investments

https://stocktrends.numerical.works/
1•mindaslab•6m ago•0 comments

Running Lua on a tiny console from 2001

https://ivie.codes/page/pokemon-mini-lua
1•Charmunk•7m ago•0 comments

Google and Microsoft Paying Creators $500K+ to Promote AI Tools

https://www.cnbc.com/2026/02/06/google-microsoft-pay-creators-500000-and-more-to-promote-ai.html
2•belter•9m ago•0 comments

New filtration technology could be game-changer in removal of PFAS

https://www.theguardian.com/environment/2026/jan/23/pfas-forever-chemicals-filtration
1•PaulHoule•10m ago•0 comments

Show HN: I saw this cool navigation reveal, so I made a simple HTML+CSS version

https://github.com/Momciloo/fun-with-clip-path
2•momciloo•11m ago•0 comments

Kinda Surprised by Seadance2's Moderation

https://seedanceai.me/
1•ri-vai•11m ago•2 comments

I Write Games in C (yes, C)

https://jonathanwhiting.com/writing/blog/games_in_c/
2•valyala•11m ago•0 comments

Django scales. Stop blaming the framework (part 1 of 3)

https://medium.com/@tk512/django-scales-stop-blaming-the-framework-part-1-of-3-a2b5b0ff811f
1•sgt•11m ago•0 comments

Malwarebytes Is Now in ChatGPT

https://www.malwarebytes.com/blog/product/2026/02/scam-checking-just-got-easier-malwarebytes-is-n...
1•m-hodges•11m ago•0 comments

Thoughts on the job market in the age of LLMs

https://www.interconnects.ai/p/thoughts-on-the-hiring-market-in
1•gmays•12m ago•0 comments

Show HN: Stacky – certain block game clone

https://www.susmel.com/stacky/
2•Keyframe•15m ago•0 comments

AIII: A public benchmark for AI narrative and political independence

https://github.com/GRMPZQUIDOS/AIII
1•GRMPZ23•15m ago•0 comments

SectorC: A C Compiler in 512 bytes

https://xorvoid.com/sectorc.html
2•valyala•16m ago•0 comments

The API Is a Dead End; Machines Need a Labor Economy

1•bot_uid_life•17m ago•0 comments

Digital Iris [video]

https://www.youtube.com/watch?v=Kg_2MAgS_pE
1•Jyaif•18m ago•0 comments

New wave of GLP-1 drugs is coming–and they're stronger than Wegovy and Zepbound

https://www.scientificamerican.com/article/new-glp-1-weight-loss-drugs-are-coming-and-theyre-stro...
4•randycupertino•20m ago•0 comments

Convert tempo (BPM) to millisecond durations for musical note subdivisions

https://brylie.music/apps/bpm-calculator/
1•brylie•22m ago•0 comments

Show HN: Tasty A.F.

https://tastyaf.recipes/about
2•adammfrank•23m ago•0 comments

The Contagious Taste of Cancer

https://www.historytoday.com/archive/history-matters/contagious-taste-cancer
2•Thevet•24m ago•0 comments

U.S. Jobs Disappear at Fastest January Pace Since Great Recession

https://www.forbes.com/sites/mikestunson/2026/02/05/us-jobs-disappear-at-fastest-january-pace-sin...
1•alephnerd•25m ago•1 comments

Bithumb mistakenly hands out $195M in Bitcoin to users in 'Random Box' giveaway

https://koreajoongangdaily.joins.com/news/2026-02-07/business/finance/Crypto-exchange-Bithumb-mis...
1•giuliomagnifico•25m ago•0 comments
Open in hackernews

After 60 Years, Diabetes Drug Found to Unexpectedly Impact the Brain

https://www.sciencealert.com/after-60-years-diabetes-drug-found-to-unexpectedly-impact-the-brain
16•ivewonyoung•4mo ago

Comments

andsoitis•4mo ago
Can highly recommend Metformin. I get mine from AgelessRX https://agelessrx.com/metformin/
orionblastar•4mo ago
I take Metformin, which balances out my psych drug weight gain by burning fat. I stick to diet and exercise, which are also factors.
aitchnyu•4mo ago
Will this help psych drug weight gain patients in general? Thinking of a fictional character who wasted years because nobody accepted her getting obese.
orionblastar•4mo ago
It depends on their metabolism. I'm not a doctor, I'm a patient. Consult a Doctor for real information. I'm just giving my opinion. Society tends to fat shame, and many can't help it because the psych drug causes glucose buildup in the blood that leads to weight gain. Metformin lowers glucose in the liver. If you are diabetic like me, you need to read your glucose meter and adjust what you eat and drink.
reify•4mo ago
The wonderful pharma industry.

They prescribe you a drug that does not cure mental illness, that you have to take your entire life, On top of that they make you obese, so you have to take another drug to help you lose weight.

Then the patient has to go through a long and arduous behavioural program to change their life style and eating habits, caused by the drugs in the first place,

The wonderful pharma industry.

High risk of weight gain anti-depressant drugs:

Amitriptyline, citalopram, clomipramine, fluvoxamine, mirtazapine, nortriptyline, paroxetine, phenelzine.

I have seen this over many years in secure psychiatric wards, with those who take antipsychotics.

Drugs do not "cure" mental illnesses. There is no chemical imbalance.

The drugs are either; chemical coshes or highly advertised and ineffective placebo.

ivell•4mo ago
I don't think there is any malicious intend when pharma produces those drugs.

The drugs are also effective in controlling some symptoms and enable people to go on with their life.

We had many centuries without those drugs, I don't think our ancestors had any better quality of life without those meds.

Psychiatric illness is complex and multiple techniques need to be employed to get some control over it.

If we are looking for a silver bullet, I agree there is none.

lm28469•4mo ago
They do pay a shit load of money to advertise them and push doctors to prescribe them so I'd say the malicious intent can definitely be at least argued about
ivell•4mo ago
Not too much different from how cola companies push their products. Though I agree that we should hold pharmaceutical companies to higher standards even in marketing and sales domains.
BizarroLand•4mo ago
There are downsides and side-effects to metformin. I started taking it for life-extension and maybe weight loss support, not for diabetes.

A few months in I started getting pain from my buttocks to my calves whenever I sit for more than 15 minutes. I was concerned that this was some new misery life had thrown at me, but when I looked up the symptoms I found that this is an uncommon side effect of metformin for some people.

This sensation greatly decreased after ceasing metformin, but has not completely subsided 2 months later.

I'm fortunate to have a standing desk at work, but the only way to temporarily mitigate this issue is to go for a long walk or otherwise exercise.

I'm not against it. It helps many people with lots of things, just putting this information out for people who might experience the same issue. Hopefully with this new understanding they will come up with alternatives with lesser issues or that work for people with my response to the medicine.