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Fragments of an Adolescent Web

https://vincent.bernat.ch/en/blog/2026-old-web-articles
1•smitty1e•2m ago•0 comments

Hims and Hers abandons copycat weight-loss drug in face of FDA probe

https://www.ft.com/content/3d4f88e9-33aa-4e1d-81af-ae6954598d63
1•bookofjoe•6m ago•1 comments

Show HN: Claude Code skill that uses Codex as MCP server for code review

https://github.com/pauhu/claude-codex-review
1•pauhu•6m ago•0 comments

The Great Reversal ( OCC and Crypto)

https://www.halogate.io/insights/great-reversal
1•CognitiveBytez•6m ago•1 comments

Show HN: I built a festival tracker that matches lineups to your music library

https://apps.apple.com/us/app/festiveo-music-festivals/id6755355854
1•kirillstyopkin•8m ago•0 comments

Ship Types, Not Docs

https://shiptypes.com/
1•howToTestFE•9m ago•0 comments

RIP Postman free tier. Here's an open-source local-first alternative

https://old.reddit.com/r/webdev/comments/1qyi3wz/rip_postman_free_tier_heres_an_opensource/
1•taubek•12m ago•0 comments

There is no Alignment Problem

1•salacryl•12m ago•0 comments

Hid Remapper

https://github.com/jfedor2/hid-remapper
1•downboots•12m ago•0 comments

Recursive Deductive Verification: A framework for reducing AI hallucinations

1•salacryl•13m ago•0 comments

Bitcoin tumbles below $70K, heavy losses in cryptocurrencies in last three weeks

https://www.bloomberg.com/news/articles/2026-02-05/bitcoin-drops-below-70-000-as-forced-deleverag...
1•heresie-dabord•13m ago•0 comments

Electrobun v1: Build fast, tiny, and cross-platform desktop apps with TypeScript

https://blackboard.sh/blog/electrobun-v1/
3•merlindru•15m ago•1 comments

Why are so many people joining cults? [video]

https://www.youtube.com/watch?v=SfG0PeMS2tQ
1•mgh2•17m ago•0 comments

Apple to Allow ChatGPT, Claude, and Gemini in CarPlay

https://www.macrumors.com/2026/02/06/apple-third-party-chatbots-carplay/
1•geox•17m ago•0 comments

Startup Idea that stops consumers paying the full price

https://shoppyhi.netlify.app
1•daviddahuang•18m ago•0 comments

GitHub Agentic Workflows

https://github.github.io/gh-aw/
1•mooreds•20m ago•0 comments

Exploring hardware-authenticated file encryption in Python

1•Lif28•22m ago•0 comments

Show HN: SEO v3 – Zero-dependency, Simple, powerful PHP SEO library

https://github.com/melbahja/seo
1•exec7•23m ago•0 comments

Show HN: Alerio – Turn Webhooks into Critical VoIP Calls (Overrides Silent Mode)

https://alerio.app/
1•royal-amrah•24m ago•1 comments

A Comprehensive Benchmark for Document Parsing and Evaluation (2025)

https://github.com/opendatalab/OmniDocBench
2•oceansky•25m ago•1 comments

When 20 Watts Beats 20 Megawatts: Rethinking Computer Design

https://smarterarticles.co.uk/when-20-watts-beats-20-megawatts-rethinking-computer-design
1•dxs•28m ago•0 comments

Canadian Province New Brunswick to Quit Using Elon Musk's X

https://www.bloomberg.com/news/articles/2026-02-05/canadian-province-new-brunswick-to-quit-using-...
8•rbanffy•30m ago•1 comments

Heterogeneous Processing: A Strategy for Augmenting Moore's Law (2006)

https://www.linuxjournal.com/article/8368
1•rbanffy•31m ago•0 comments

Show HN: Mvvmm – Firecracker-like mini virtual machine monitor in ~2000 LoC

https://github.com/mistivia/mvvmm
1•mistivia•33m ago•0 comments

Search anything said on a podcast, speaker-labeled and speaker-tracked

https://poddley.com
1•onesandofgrain•34m ago•1 comments

Canada, better the 28th EU member than the 51st US state

https://www.lemonde.fr/en/opinion/article/2026/02/05/canada-better-the-28th-eu-member-than-the-51...
5•u1hcw9nx•34m ago•1 comments

Show HN: Team of agent researchers read things I don't have time to and brief me

https://read-fast.replit.app/
1•thomoliverz•36m ago•2 comments

Show HN: Chaos Agents – Run chaos experiments with Agents

https://github.com/system32-ai/chaos-agents
3•linuxarm64•37m ago•0 comments

Almostnode – Node.js in the Browser

https://github.com/macaly/almostnode
1•ushakov•37m ago•0 comments

Mount Fuji cherry blossom festival canceled due to overtourism

https://www.japantimes.co.jp/news/2026/02/05/japan/japan-mount-fuji-cherry-festival-overtourism/
3•akyuu•39m ago•1 comments
Open in hackernews

Rewriting the Grand Plan of Clinical Neuroscience

https://www.psychiatrymargins.com/p/rewriting-the-grand-plan-of-clinical
2•wiry•4mo ago

Comments

reify•4mo ago
For me the USA verison of Psychiatry that has failed everyone.

Since the end of WW2 when the the USA determined that their way was the only way.

From the 1920s, there was tension between the Americans and Europeans over it

The dominant model for thinking about thinking across the Atlantic was Behaviourism, which depended on animals in laboratories, ‘controlled’ experiments, and various other trappings of science.

The Diagnostic and Statistics Manual was borne of the belief about control over the worlds psychiatry from those in the USA.

It has failed. There is no cure for any psychiatric illness or diagnoses. There are of course chemical coshes used in secure psychiatric wards and that is it, the rest are ineffective placebo's that hold many dangers.

Why did the psychiatric community allow the fake "Chemical Imbalance" claims to remain unchallanged for far too long. Simply because they have a hand in big Pharma, and nothing more.

I even taught this complete bullshit to undergratuate students. I drew a brain synapse on a blackboard, with two men in small rowing boats, one boat transfering serotonin back and forth between the synapse, and the other boat blocking the first boat from returning (reuptaking), to simplify how SSRI's work. What a load of bollocks! I feel terrible for having done that.

Then in the 1980's came the SSRI's.

SSRI antidepressants have different names throughout the world but the mechanism of action is the same.

Depression is a natural response to sadness and loss. We humans are well prepared to work through sadness and loss, we dont need drugs to do that.

I have seen far too many people diagnosed with clinical depression and prescribed SSRI's, because they meet 5 criteria in the DSM-5, when they were not clinically depressed.

There was a huge increase in teenage suicides in the 90's. They reduced prescribing to teenagers but assumed adults were OK. So they put warning labels on the packaging for adults, who, in my experience were, and still are, dying of suicides because of the medication they were taking.

I have spent my time in secure psychiatric wards and that is where you find the clinically depressed, who may, or may not, benefit from some sort of medicalised intervention.

SSRI's are generally prescribed on the basis they cure a ‘chemical imbalance’. No chemical imbalances have ever been proven to exist. No tests exist to support this theory, and it is a societal belief based on pharmaceutical marketing.

Instead of correcting biochemical imbalances, the drugs cause biochemical imbalances. Deterioration seen in many patients is not caused by an inherent disease process within the brain, rather a by toxic exposures to psychiatric medication.

I have seen far to many people prescribed anti-depressants for 10 years or more.

I spoke to chap recently who has been, and still is, taking Sertraline for the past 11 years for depression after his mother died, without any follow up review.

The man was a walking Zombie. 11 years of taking an anti-depressant every day for no reason.

This is a human being who was suffering from sadness and loss. There is no need to prescribe any medication for him.

Then there is the elephant in the room: Paradoxical Reaction:

Animal studies demonstrate when initially given Fluoxetine (Prozac), an SSRI Antidepressant , the brain shuts down its own production of serotonin, causing a paradoxical effect or opposite effect on the level of serotonin.

A large 2007 double-blind study of fluoxetine in patients with chronic Depression revealed that nearly one third (30.4%) experienced early worsening of symptoms, defined as a 5-point increase on the Hamilton Depression Rating Scale (HAM-D).

The study emphasized that paradoxical effects are not just isolated anecdotes but designated as “common” and thus represent a measurable risk for a significant portion of patients.

The Suicide Prevention Strategy 2013-2016 included the statistics that 59% of the 5,119 people who died by suicide between 2009 and 2015 in Scotland had at least one mental health drug prescription dispensed within 12 months of death. 82% were prescribed an antidepressant alone or in combination with another drug.

Why are those in the medical professions still prescribing SSRI's???

then there is Post-SSRI Sexual Dysfunction, now recognised in the DSM-5, which they managed to keep quite and deny for 30 years. yet again, I worked with people who suffered with Post-SSRI Sexual Dysfunction 20 years ago.