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Extrachromosomal DNA–Driven Oncogene Evolution in Glioblastoma

https://aacrjournals.org/cancerdiscovery/article/doi/10.1158/2159-8290.CD-24-1555/764257/Extrachromosomal-DNA-Driven-Oncogene-Spatial
2•PaulHoule•2h ago

California bans masks meant to hide law enforcement officers' identities

https://www.npr.org/2025/09/20/nx-s1-5548532/newsom-trump-masked-ice-agents
1•1659447091•57s ago•0 comments

Rare flesh eating-bacteria claims another victim officials urge take precautions

https://www.dailymail.co.uk/health/article-15118479/flesh-eating-bacteria-Vibrio-vulnificus-Louis...
1•Bender•1m ago•0 comments

Reframing Biblical interpretation helps religious students accept evolution

https://www.psypost.org/reframing-biblical-interpretation-helps-religious-students-accept-evolution/
1•01-_-•2m ago•0 comments

VPN usage at risk in Michigan under new proposed adult content law

https://www.techradar.com/vpn/vpn-privacy-security/vpn-usage-at-risk-in-michigan-under-new-propos...
1•akyuu•2m ago•0 comments

A New Kind of Code

https://registerspill.thorstenball.com/p/a-new-kind-of-code
1•goranmoomin•3m ago•0 comments

Magnesium, the microbiome, and reducing the risk of colon cancer

https://newatlas.com/health-wellbeing/magnesium-supplements-gut-bacteria-colorectal-cancer/
1•01-_-•3m ago•0 comments

How a Vibrator Helped Me Debug a Motorcycle Brake Light System

https://bikesafe.me/blogs/news/how-a-vibrator-helped-me-debug-a-motorcycle-brake-light-system
1•CharlesW•6m ago•0 comments

Linux Ready to Upstream Support for Google's PSP Encryption for TCP Connections

https://www.phoronix.com/news/PSP-Encryption-Linux-6.18
3•Bender•7m ago•0 comments

Haiti: The Most Important Country in the World – (Class #1) [video]

https://www.youtube.com/watch?v=mjliyakWVl4&list=PL5VfCdafDjf8hJhJv3N3W-uax1dMbf1yI&index=8
1•evanjrowley•10m ago•0 comments

A simulator significantly inspired by the first commercial transistor computer

https://git.sr.ht/~nkali/mv950toy
2•todsacerdoti•13m ago•0 comments

Characterizing Fitness Landscape Structures in Prompt Engineering

https://arxiv.org/abs/2509.05375
2•PaulHoule•14m ago•0 comments

Ask HN: Does vibecoding destroy teens learning to code, or help them?

1•jimmydin7•15m ago•0 comments

The Homebuyer's Guide to Martian Settlement – Universe Today

https://www.universetoday.com/articles/the-homebuyers-guide-to-martian-settlement
1•rbanffy•19m ago•0 comments

Why Write About Degenerates?

https://secondvoice.substack.com/p/why-write-about-degenerates
1•paulpauper•20m ago•0 comments

Don't Be a Sucker [video]

https://www.youtube.com/watch?v=vGAqYNFQdZ4
1•alecst•20m ago•0 comments

Review: Project Xanadu – The Internet That Might Have Been

https://www.astralcodexten.com/p/your-review-project-xanadu-the-internet
5•paulpauper•21m ago•0 comments

Ask HN: Production deployed full AI generated applications

1•indianmouse•21m ago•0 comments

Tunnel your local HTTP(s) server to the world (Crystal port of unjs/untun)

https://github.com/krthr/untun.cr
3•krthr•24m ago•0 comments

Show HN: Freeing GPUs stuck by runaway jobs

https://github.com/kagehq/gpu-kill
2•lexokoh•24m ago•0 comments

Microstacks or Megadependencies over at Webdevcon 2025

https://berthub.eu/articles/posts/microstacks-or-megadependencies-webdev/
3•Bogdanp•24m ago•0 comments

Check Your References When Restoring a Car

https://www.caranddriver.com/features/g65654286/1980-nissan-280zx-1984-300zx-factory-restoration/
1•insane_dreamer•25m ago•1 comments

LaLiga's Anti-Piracy Crackdown Triggers Widespread Internet Disruptions in Spain

https://reclaimthenet.org/laligas-anti-piracy-crackdown-triggers-widespread-internet-disruptions
12•akyuu•27m ago•1 comments

Show HN: The Atlas – I Built a 3D Universe Simulation with Python and Three.js

https://github.com/SurceBeats/Atlas
1•SurceBeats•28m ago•0 comments

Ray Bradbury in 1984, interviewed about Fahrenheit 451 becoming a computer game

https://books.google.com/
1•ohjeez•29m ago•0 comments

Clean hydrogen is facing a big reality check

https://www.technologyreview.com/2025/09/18/1123818/hydrogen-reality-check-china/
2•rbanffy•30m ago•0 comments

The Future of AI Codecs: Specialisation

https://deeprender.ai/blog/future-ai-codecs-specialisation
1•ksec•31m ago•0 comments

RIP John H. Wolfe, the inventor of model-based clustering for continuous data

https://www.dignitymemorial.com/obituaries/san-diego-ca/john-wolfe-11789597
1•ohjeez•31m ago•1 comments

How AI can make coupon codes work – Kupondi

https://kupondi.com/?lang=en
1•pr-lanch•32m ago•0 comments

Oxford loses top 3 university ranking for the first time

https://hotminute.co.uk/2025/09/19/oxford-loses-top-3-university-ranking-for-the-first-time/
39•ilamont•33m ago•23 comments

Three Years and 100 Commits Later: A Reflection

https://priyavr.at/blog/100-commits/
1•prvt•34m ago•1 comments