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The API Is a Dead End; Machines Need a Labor Economy

1•bot_uid_life•25s ago•0 comments

Digital Iris [video]

https://www.youtube.com/watch?v=Kg_2MAgS_pE
1•Jyaif•1m ago•0 comments

New wave of GLP-1 drugs is coming–and they're stronger than Wegovy and Zepbound

https://www.scientificamerican.com/article/new-glp-1-weight-loss-drugs-are-coming-and-theyre-stro...
2•randycupertino•3m ago•0 comments

Convert tempo (BPM) to millisecond durations for musical note subdivisions

https://brylie.music/apps/bpm-calculator/
1•brylie•5m ago•0 comments

Show HN: Tasty A.F.

https://tastyaf.recipes/about
1•adammfrank•5m ago•0 comments

The Contagious Taste of Cancer

https://www.historytoday.com/archive/history-matters/contagious-taste-cancer
1•Thevet•7m ago•0 comments

U.S. Jobs Disappear at Fastest January Pace Since Great Recession

https://www.forbes.com/sites/mikestunson/2026/02/05/us-jobs-disappear-at-fastest-january-pace-sin...
1•alephnerd•7m ago•0 comments

Bithumb mistakenly hands out $195M in Bitcoin to users in 'Random Box' giveaway

https://koreajoongangdaily.joins.com/news/2026-02-07/business/finance/Crypto-exchange-Bithumb-mis...
1•giuliomagnifico•7m ago•0 comments

Beyond Agentic Coding

https://haskellforall.com/2026/02/beyond-agentic-coding
3•todsacerdoti•9m ago•0 comments

OpenClaw ClawHub Broken Windows Theory – If basic sorting isn't working what is?

https://www.loom.com/embed/e26a750c0c754312b032e2290630853d
1•kaicianflone•11m ago•0 comments

OpenBSD Copyright Policy

https://www.openbsd.org/policy.html
1•Panino•11m ago•0 comments

OpenClaw Creator: Why 80% of Apps Will Disappear

https://www.youtube.com/watch?v=4uzGDAoNOZc
2•schwentkerr•15m ago•0 comments

What Happens When Technical Debt Vanishes?

https://ieeexplore.ieee.org/document/11316905
2•blenderob•17m ago•0 comments

AI Is Finally Eating Software's Total Market: Here's What's Next

https://vinvashishta.substack.com/p/ai-is-finally-eating-softwares-total
3•gmays•17m ago•0 comments

Computer Science from the Bottom Up

https://www.bottomupcs.com/
2•gurjeet•17m ago•0 comments

Show HN: A toy compiler I built in high school (runs in browser)

https://vire-lang.web.app
1•xeouz•19m ago•0 comments

You don't need Mac mini to run OpenClaw

https://runclaw.sh
1•rutagandasalim•20m ago•0 comments

Learning to Reason in 13 Parameters

https://arxiv.org/abs/2602.04118
2•nicholascarolan•22m ago•0 comments

Convergent Discovery of Critical Phenomena Mathematics Across Disciplines

https://arxiv.org/abs/2601.22389
1•energyscholar•22m ago•1 comments

Ask HN: Will GPU and RAM prices ever go down?

1•alentred•22m ago•0 comments

From hunger to luxury: The story behind the most expensive rice (2025)

https://www.cnn.com/travel/japan-expensive-rice-kinmemai-premium-intl-hnk-dst
2•mooreds•23m ago•0 comments

Substack makes money from hosting Nazi newsletters

https://www.theguardian.com/media/2026/feb/07/revealed-how-substack-makes-money-from-hosting-nazi...
5•mindracer•24m ago•0 comments

A New Crypto Winter Is Here and Even the Biggest Bulls Aren't Certain Why

https://www.wsj.com/finance/currencies/a-new-crypto-winter-is-here-and-even-the-biggest-bulls-are...
1•thm•24m ago•0 comments

Moltbook was peak AI theater

https://www.technologyreview.com/2026/02/06/1132448/moltbook-was-peak-ai-theater/
1•Brajeshwar•25m ago•0 comments

Why Claude Cowork is a math problem Indian IT can't solve

https://restofworld.org/2026/indian-it-ai-stock-crash-claude-cowork/
2•Brajeshwar•25m ago•0 comments

Show HN: Built an space travel calculator with vanilla JavaScript v2

https://www.cosmicodometer.space/
2•captainnemo729•25m ago•0 comments

Why a 175-Year-Old Glassmaker Is Suddenly an AI Superstar

https://www.wsj.com/tech/corning-fiber-optics-ai-e045ba3b
1•Brajeshwar•25m ago•0 comments

Micro-Front Ends in 2026: Architecture Win or Enterprise Tax?

https://iocombats.com/blogs/micro-frontends-in-2026
2•ghazikhan205•28m ago•1 comments

These White-Collar Workers Actually Made the Switch to a Trade

https://www.wsj.com/lifestyle/careers/white-collar-mid-career-trades-caca4b5f
1•impish9208•28m ago•1 comments

The Wonder Drug That's Plaguing Sports

https://www.nytimes.com/2026/02/02/us/ostarine-olympics-doping.html
1•mooreds•29m ago•0 comments
Open in hackernews

Bay Area biotech Arsenal Bio lays off half its workers a yr after raising $325M

https://www.sfgate.com/tech/article/arsenal-biotech-lays-off-half-21061658.php
6•randycupertino•4mo ago

Comments

duxup•4mo ago
Bio tech and start up style ... failing fast seems like an incompatible thing.

Bio tech seems like it often requires tons of iterations on an idea that take a very long time. Meanwhile start up land is often "nope that first shot didn't get any uptake, guess we're done".

randycupertino•4mo ago
Also BMS recently pulled out of their collaboration with Arsenal so in this case they were probably counting on more easy $$ from that partnership after burning through their previous $325m raise.
randycupertino•4mo ago
Even if the science is strong, so many flash in the pan cell therapy startups just can't execute on clinical operations. They get through IPO on investor FOMO and promises of exciting times ahead but then the stock tanks tanks when the trials take forever, cost more than anticipated and no other drugs to fall back on.

Rough market for the 127 people laid off.