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Ibuprofen: An everyday drug might offer protection against cancer

https://medicalxpress.com/news/2025-10-ibuprofen-everyday-drug-cancer.html
5•OutOfHere•2h ago

Comments

OutOfHere•2h ago
Be careful, even for prevention, because even a single use of ibuprofen can very easily leave one with a gastrointestinal ulcer, even if taken with food or on a full stomach. Taking omeprazole at +0 hours and again at +12 hours lowers this risk, although I wonder if vonoprazan would be better suited. If care is not taken, healing the ulcer can take several weeks via glutamine, vitamin C, fresh cabbage juice, collagen hydrolysate, etc. Also, it doesn't really seem to make sense to take ibuprofen if one isn't struggling with inflammatory pain.

Can AI Avoid the Enshittification Trap?

https://www.wired.com/story/can-ai-escape-enshittification-trap/
1•CharlesW•1m ago•0 comments

Show HN: JIT compilation of NES ROMs / 6502 programs to .NET MSIL

https://github.com/KallDrexx/Dotnet6502
1•KallDrexx•2m ago•0 comments

Birchdocs, my personal docs site

https://birchdocs.tokyo
2•LinguaBrowse•2m ago•1 comments

Amazon outage takes down Venmo, Ring, Reddit and much of the internet

https://www.techradar.com/news/live/amazon-web-services-alexa-ring-snapchat-fortnite-down-october...
2•CharlesW•3m ago•0 comments

TSMC's dilemma, OpenAI or Oracle, prediction on ambient computing

https://myriadperspectives.com/p/openais-road-to-become-a-hyperscaler
1•leecmjohnny•4m ago•0 comments

Why and how I rewrote these Obsidian plugins

https://johnwhiles.com/posts/obsidian-plugins
2•jwhiles•5m ago•0 comments

OpenAI is losing about three times more money than it's earning

https://www.theregister.com/2025/10/15/openais_chatgpt_popular_few_pay/
1•hansmayer•5m ago•0 comments

Show HN: Spark Slider – Lightweight React Carousel (12KB, TypeScript)

https://github.com/AshBuk/framer-motion-spark-slider
1•AshBuk•6m ago•1 comments

MTEB v2: Evaluation of embedding and retrieval systems for more than just text

https://huggingface.co/blog/isaacchung/mteb-v2
1•lairv•6m ago•0 comments

Subretinal Photovoltaic Implant Restores Vision in Geographic Atrophy Due to AMD

https://www.nejm.org/doi/10.1056/NEJMoa2501396
1•bookofjoe•7m ago•0 comments

Multi-Region Deployments with CDK

https://makingituptech.substack.com/p/multi-region-deployments-with-cdk
1•djlewald•8m ago•0 comments

Benefits of Undefined Behavior

https://mazzo.li/posts/undefined-behavior.html
2•01-_-•8m ago•0 comments

Show HN: Guardrail Layer – self-hosted AI data layer for secure DB chat

https://github.com/tyoung1996/guardrail-layer
1•tcodeking•9m ago•0 comments

AWS Cut Jobs 3 Months Ago

https://www.reuters.com/business/retail-consumer/amazons-aws-cloud-computing-unit-cuts-least-hund...
2•thisismytest•9m ago•0 comments

Apple Pioneer Bill Atkinson Was a Secret Evangelist of the 'God Molecule'

https://www.wired.com/story/apple-pioneer-bill-atkinson-was-a-secret-evangelist-of-the-god-molecule/
1•bookofjoe•11m ago•1 comments

Disaster Insured Losses Top $100B for Sixth Year in a Row

https://www.bloomberg.com/news/articles/2025-10-15/disaster-insured-losses-top-100-billion-for-si...
1•toomuchtodo•13m ago•1 comments

Signs of AI Writing on Wikipedia

https://flowingdata.com/2025/10/20/signs-of-ai-writing-on-wikipedia/
2•Hard_Space•16m ago•1 comments

Fury Mounts over a Global A.I. Frenzy

https://www.nytimes.com/2025/10/20/technology/ai-data-center-backlash-mexico-ireland.html
2•moneycantbuy•17m ago•0 comments

AI New Mirror Engine

https://github.com/fieryseaturtle-dotcom/My-Mirror-Engine-for-AI
1•FierySeaTurtle•18m ago•0 comments

Got a Netflix letter about 30k failed login attempts traced to my IP

https://old.reddit.com/r/SaladChefs/comments/1oa3k5o/got_a_netflix_letter_about_30000_failed_login/
3•takoid•19m ago•1 comments

First-run with agent skills from Anthropic

https://macwright.com/2025/10/20/agent-skills
1•stevekrouse•19m ago•0 comments

Why the numbers 6-7 are driving math teachers up the wall

https://www.npr.org/2025/10/19/nx-s1-5578929/why-the-numbers-6-7-are-driving-math-teachers-up-the...
2•ikeashark•19m ago•0 comments

Show HN: I built a user-friendly Google Analytics alternative

https://www.statflows.com/
1•UnicornSHARP•20m ago•0 comments

Roast me if you can

https://novad.app
2•nonmaskable•20m ago•1 comments

Ask HN: Is claude-agent-sdk-python Ready for Production? (Spoiler: No)

1•jujumilk3•21m ago•0 comments

The Curse of the Eternally Urgent

https://gettingthingsdone.com/2025/05/the-curse-of-the-eternally-urgent/
2•lucidplot•24m ago•0 comments

Windows 11 update knocks out USB mice, keyboards in recovery mode

https://www.theregister.com/2025/10/20/microsoft_bug_keyboard_mouse/
3•beardyw•25m ago•0 comments

Show HN: Turn Chrome into an Agent

https://firmware.ai
1•cgilly2fast•26m ago•0 comments

Show HN: GitScribe – Because Social Media Sucks (for Devs)

https://github.com/FayZ676/gitscribe
1•fayz676•26m ago•0 comments

Anthropic and Cursor Spend This Much on Amazon Web Services

https://www.wheresyoured.at/costs/
16•isoprophlex•29m ago•6 comments