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Technology for Humans: Conversation with Ruby Central's Executive Director, Sha

https://www.youtube.com/watch?v=nKpo68g9dEk
1•todsacerdoti•5m ago•0 comments

The Tech CEO Campaign to Stop Trump from Sending Troops to San Francisco

https://www.wsj.com/politics/policy/san-francisco-troops-tech-ceos-45623a7f
2•panic•6m ago•0 comments

Reddit's 'AI Scraping' Lawsuit Is an Attack on the Open Internet

https://www.techdirt.com/2025/10/24/reddits-ai-scraping-lawsuit-is-an-attack-on-the-open-internet/
1•hn_acker•8m ago•0 comments

UDP Isn't Unreliable, It's a Conertible

https://www.proxylity.com/articles/udp-is-a-convertible.html
1•mlhpdx•8m ago•0 comments

US agency asks Tesla about 'Mad Max' driver assistance mode

https://www.reuters.com/business/autos-transportation/us-agency-asking-tesla-about-mad-max-driver...
1•tempestn•21m ago•0 comments

7 Strategies for Increasing Your "Neuroplasticity"

https://www.insidehook.com/wellness/increase-neuroplasticity
2•RickJWagner•22m ago•0 comments

Airflow at Asapp: Enhancing AI-Powered Contact Centers (2024)

https://uditsaxena.bearblog.dev/airflow-asapp-ai/
1•wavelander•23m ago•0 comments

Powerful and precise multi-color lasers now fit on a single chip

https://phys.org/news/2025-10-powerful-precise-multi-lasers-chip.html
1•PaulHoule•26m ago•0 comments

Hacker Documentary: Unauthorized Access by Annaliza Savage (1994)

https://www.youtube.com/watch?v=fDk82bLYscg
1•doener•27m ago•0 comments

Energy Efficient Housing in Sweden (1984, PDF)

https://www.aceee.org/files/proceedings/1984/data/papers/SS84_Panel10_Paper_09.pdf
1•starkparker•27m ago•0 comments

Technical experts have zero customers

https://www.ivan.codes/thoughts/technical-experts-have-zero-customers
2•gboesel•30m ago•0 comments

US Auto Plants Weeks Away from Chip Shutdowns

https://www.bloomberg.com/news/articles/2025-10-24/us-auto-plants-weeks-away-from-chip-shutdowns-...
1•JumpCrisscross•34m ago•0 comments

The Leadership and Happiness Laboratory

https://www.happiness.hks.harvard.edu
2•wslh•36m ago•0 comments

The Peter Principle and exploiting overconfident workers

https://marginalrevolution.com/marginalrevolution/2025/10/the-peter-principle-and-exploiting-over...
5•paulpauper•37m ago•0 comments

Putin Calls Up Reserves to Protect Russia from Ukraine's Drones

https://www.bloomberg.com/news/articles/2025-10-24/putin-calls-up-russian-reserves-to-protect-inf...
3•JumpCrisscross•37m ago•0 comments

WTF Are Agents?

https://www.ashpreetbedi.com/articles/wtf-is-an-agent
2•bediashpreet•38m ago•1 comments

Critical Windows WSUS flaw actively exploited

https://www.bleepingcomputer.com/news/security/hackers-now-exploiting-critical-windows-server-wsu...
2•heresie-dabord•41m ago•0 comments

As Texas power demand surges, solar, wind and storage carry the load

https://electrek.co/2025/10/24/texas-power-demand-surges-solar-wind-and-storage-carry-the-load/
1•toomuchtodo•41m ago•0 comments

Poland, Romania foil Russian exploding parcels plot, Warsaw says

https://www.reuters.com/world/polish-services-detained-eight-people-suspected-preparing-acts-sabo...
5•danielam•43m ago•0 comments

Would the .NET community benefit from an open-source MassTransit fork?

2•Nakib•43m ago•0 comments

Sustained growth through creative destruction: Nobel laureates Philippe Aghion

https://cepr.org/voxeu/columns/sustained-growth-through-creative-destruction-nobel-laureates-phil...
3•paulpauper•45m ago•0 comments

Congratulations, Publicly

https://www.workingtheorys.com/p/congratulations-publicly
1•paulpauper•46m ago•0 comments

Halo's 25th anniversary brings game to PlayStation

https://www.theverge.com/news/805174/halo-campaign-evolved-remake-xbox-ps5-release-date
2•avonmach•48m ago•0 comments

Shame of a Nation – The Pardon of Changpeng Zhao

https://www.youtube.com/watch?v=AmcMiLr21z0
2•doener•48m ago•0 comments

New AI Tool

1•aiipassword•49m ago•0 comments

A Man Behind Grand Theft Auto Just Called AI a "Parlor Trick"

https://www.gtaboom.com/the-man-behind-grand-theft-auto-just-called-ai-a-parlor-trick-7cc4
2•mdotk•50m ago•1 comments

Shop Together, Even When Apart

https://apps.apple.com/us/app/simplist-list-made-simple/id721184185
1•meghagulati•53m ago•0 comments

PhotoDemon: Free, portable, open-source photo editor

https://photodemon.org/
1•atilimcetin•53m ago•0 comments

Mean Images

https://newleftreview.org/issues/ii140/articles/hito-steyerl-mean-images
2•bonefishgrill•54m ago•0 comments

Chinese students pocketed £157k train refunds in delay repay scam

https://www.telegraph.co.uk/news/2025/10/22/chinese-students-pocket-157k-in-delay-repay-train-scam/
3•flykespice•56m ago•0 comments
Open in hackernews

MRI Contrast Agent Causes Harmful Metal Buildup in Some Patients [study]

https://www.ormanager.com/briefs/study-mri-contrast-agent-causes-harmful-metal-buildup-in-some-patients/
56•nikolay•2h ago

Comments

hereme888•1h ago
You know what other metal stays in the body, permanently bound to bone and other organs? Bismuth, as in bismuth salycilate, aka Peptobismol. A tiny % actually stays in your body.
ToDougie•1h ago
Can you please share more?
DennisP•1h ago
Does that cause any symptoms? Because apparently this can, and they tell you how to avoid it.

> Lead author Dr Brent Wagner told Newsweek he personally avoids vitamin C when undergoing MRI with contrast, citing its potential to increase gadolinium reactivity. “Metabolic milieu,” including high oxalic acid levels, could explain why some individuals experience severe symptoms while others do not, he said.

Avoiding high-oxalic foods for a few days before the MRI also seems like a good idea. Just check the diet for calcium oxalate kidney stones.

gclawes•1h ago
Every time I've gotten an MRI the doctors and techs have sworn up and down it's impossible for this stuff to stick around. Getting tired of not being able to believe what doctors say...
bamboozled•1h ago
The other day I had to get a CT scan, I was kind of annoyed I wasn't offered and MRI, and here we are.

I hold a different opinion to you though, I'm glad doctors are always learning more while generally operating with good /extremely good intentions.

byryan•1h ago
Really wish more people had that mind set. Practicing medicine isn't easy, especially in the US when you have to battle the insane insurance industry.
margalabargala•1h ago
> I hold a different opinion to you though, I'm glad doctors are always learning more while generally operating with good /extremely good intentions.

I agree. Expecting perfection from humans, even experts, is not reasonable and is frankly counterproductive.

Willful ignorance is one thing, but people who genuinely attempt to do the right thing at worst just need to be steered slightly differently.

torstenvl•51m ago
Except that a disturbing number of doctors insist that they are always right and you are always wrong.

A year ago, one insisted vehemently—to the point of yelling—that I shouldn't be supplementing Vitamin K because my potassium levels were fine.

drum55•1h ago
That's surprising, it's at least casually known that they're bio accumulative to some extent. I've joked to the techs before about gadolinium eventually accumulating enough to not be necessary if you do it with enough frequency. Realistically though any situation that you're doing the contrast you're probably at a lot more risk of whatever they've found than from the contrast agent.
smeej•59m ago
I had to have contrast to diagnose a simple cyst, which is entirely asymptomatic and was discovered by accident in the background of a cardiac MRI (family history of SCD, but my own heart is fine).

You're making me feel lucky about what was otherwise a very unpleasant experience!

zoeysmithe•1h ago
The data until recently suggested that, so thats the risk you take. Would you rather be living in ancient greece and shoved full of hemlock leaves for arthritis? Or have a 19th century surgeon remove your appendix?

There's risk in life and odds-wise if you're in the developed West, you're going to get care and medicine that will greatly prolong your life.

Also this paper is super vague. What percent of people even get this? How long does it last? They havent even done a study to see how long it lasts yet. I have a feeling this isnt going to be our generation's asbestos or thalidomide.

That being said, you should decide your own risk profile. If MRI gives you concerns there are alternatives that dont involve contrast.

appreciatorBus•1h ago
No one is asking to go back to Ancient Greece.

But given our track record, a little humility would go along way.

When a highly educated doctor tells you that something is safe, a person is going to assume that means that someone somewhere has proven that the substance is safe. If what they really mean is that no one really knows, but so far, no experiments have been able to prove danger, then we should say that instead.

bawolff•1h ago
By that definition, nobody knows anything is safe.
shakna•1h ago
Or to not click through multiple layers of clickbait: https://doi.org/10.1016/j.mri.2025.110383

Unfortunately, the article isn't much better. It has as an underpinning, a corrected paper: https://doi.org/10.1093/ndt/gfl294

anon291•1h ago
The link between NSF and gadolinium-based agents has been known for almost two decades and is common knowledge in the industry.
Neywiny•1h ago
Yes. The problem is that it's common in the industry. But it's ultimately up to the patient. Maybe alone. Pretty much guaranteed scared. Undereducated, worrying about their likely life threatening potential illness or injury. That's basically under duress.
bawolff•54m ago
What are you proposing instead? Should patients just die of their illness instead?

Medical procedures have risk, some are small risk some are higher risk. There are none that are 100% safe. Doctors are supposed to evaluate if the risk is worth the value the procedure would supply.

What is the alternative to the status quo that you would propose?

Neywiny•49m ago
There's a big difference between not getting the MRI and getting the MRI without gadolinium. My suggestion is to ensure that people know the risks outside of just the people who work in it. I'm not sure how that didn't get across in my original comment. With your comprehension skills, you are at an increased risk of falling victim to this exact scenario
bonsai_spool•37m ago
>>> Yes. The problem is that it's common in the industry. But it's ultimately up to the patient. Maybe alone. Pretty much guaranteed scared. Undereducated, worrying about their likely life threatening potential illness or injury. That's basically under duress.

> There's a big difference between not getting the MRI and getting the MRI without gadolinium. My suggestion is to ensure that people know the risks outside of just the people who work in it. I'm not sure how that didn't get across in my original comment. With your comprehension skills, you are at an increased risk of falling victim to this exact scenario

I don't see anything wrong with the GP's comprehension skills.

Anyway, every procedure has risk - and no procedure is recommended if there is not an offsetting clinical benefit. There are clear guidelines for when gadolinium is to be used for an MRI and the guidelines factor in risk for 'NSF'.

bawolff•35m ago
My understanding was that gadolinium was already only used in cases where a normal MRI would be ineffective.

I don't know how the risk is actually communicated to patients. I imagine it varries by country. However, normal medical ethics would be to explain risks to the patients. Is there a reason to believe that isn't happening?

fluidcruft•34m ago
There have been no cases of NSF in over ten years after newer gadolinium contrast agents have displaced the problematic ones.
burnt-resistor•33m ago
That's somewhere between a Hobson's choice and Russian roulette.
Neywiny•1h ago
This is very interesting to see on here. My mother was the dissenting vote on an FDA panel on this. There are articles about it. I'll copy her words (as reported by something but seems legit)

> She said that the FDA's plan doesn't go far enough.

> "It's hard to dismiss an anecdotal report when you are the anecdote. When a patient is finally tested and found to have gadolinium retention, there's no FDA-approved antidote. So what does the patient do?"

And I want to reiterate that she was "the" no not "a" no. I don't know if her vote alone is what's caused more research into this. But it's probably the thing I brag about her the most. Even though everybody else said it was fine or abstained, she stood strong. If you look up the articles from the time of the panel (2017) you'll see a lot of articles about this panel and how she was the sole no vote. Included in that was a public post from Chuck Norris praising her. He was going to come out to meet us but I think it was a bad Texas hurricane season so that fell through

fluidcruft•37m ago
I mean there have been no reported cases of NSF in the last ten years after certain gadolinium agents were removed from the market.
unsupp0rted•59m ago
Nobody told me gadolinium can be retained before I had it the first couple times.

Like somebody else mentioned, they swore up and down it's perfectly safe.

bonsai_spool•36m ago
> Nobody told me gadolinium can be retained before I had it the first couple times.

The reason these publications exist is that this is new knowledge

> Like somebody else mentioned, they swore up and down it's perfectly safe.

I am positive that you were not told that '[gadolinium] is perfectly safe' because there is a well-known complication of gadolinium administration. It's rare, but it's mentioned in every consent form.

bonsai_spool•46m ago
This is a poor explanation of an older publication, when the actual new work has a good description:

https://www.frontiersin.org/journals/toxicology/articles/10....