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Beating AlphaFold3
https://genesis.ml/news/introducing-pearl-the-next-generation-foundation-model-for-drug-discovery/
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slashdave
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2h ago
Comments
slashdave
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2h ago
First model to clearly surpass AlphaFold 3 on protein-ligand structure prediction
KDE Linux deep dive: package mgmt is amazing, which is why we don't include it
https://pointieststick.com/2025/10/25/kde-linux-deep-dive-package-management-is-amazing-which-is-...
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MaximilianEmel
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57s ago
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0 comments
MCP Gateway and Registry: Enterprise-Grade Tool Governance for AI Agents
https://github.com/agentic-community/mcp-gateway-registry
1
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aarora79
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1m ago
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1 comments
Aisuru Botnet Shifts from DDoS to Residential Proxies
https://krebsonsecurity.com/2025/10/aisuru-botnet-shifts-from-ddos-to-residential-proxies/
1
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feross
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3m ago
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0 comments
Show HN: PDF to Text Without OCR
https://www.signmypdf.com/tools/extract-text-from-pdf/
1
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aqrashik
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3m ago
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0 comments
The fleet is the data center
https://twitter.com/niccruzpatane/status/1983227043887058974
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delichon
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4m ago
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0 comments
OpenAI completes restructure as for-profit company
https://www.semafor.com/article/10/28/2025/openai-completes-restructure-as-for-profit-company
1
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smithcoin
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7m ago
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0 comments
The Smallest Pixel in the World
https://www.uni-wuerzburg.de/en/news-and-events/news/detail/news/hecht-science-advances/
1
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layer8
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9m ago
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1 comments
Death by Scrolling
https://store.steampowered.com/app/3773590/Death_by_Scrolling/
1
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doener
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10m ago
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0 comments
HoloDoom [video]
https://www.youtube.com/watch?v=Ozzpirkhi5c
1
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garaetjjte
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11m ago
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0 comments
Univ of Miami scientists launch accessible global climate modeling framework
https://news.miami.edu/rosenstiel/stories/2025/09/university-of-miami-scientists-launch-accessibl...
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susiecambria
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12m ago
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0 comments
AI's labor market squeeze tightens
https://www.axios.com/2025/10/28/ai-jobs-amazon-layoffs
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moneycantbuy
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18m ago
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1 comments
FCC Changes Course on the Price of Prisoners' Phone Calls
https://www.nytimes.com/2025/10/28/upshot/prisoners-phone-calls-prices.html
2
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coloneltcb
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21m ago
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0 comments
Semantic Compression with Large Language Models
https://arxiv.org/abs/2304.12512
1
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manikandaraj
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25m ago
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1 comments
ChatGPT Atlas
https://openai.com/index/introducing-chatgpt-atlas/
1
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manikandaraj
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27m ago
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1 comments
Galactic Empires May Live at the Center of Our Galaxy, Hence Why We Don't Hear
https://www.universetoday.com/articles/galactic-empires-may-live-at-the-center-of-our-galaxy-henc...
2
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atilimcetin
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31m ago
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1 comments
Saint Pierre and Miquelon
https://en.wikipedia.org/wiki/Saint_Pierre_and_Miquelon
1
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derbOac
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32m ago
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0 comments
Opportunistic Mutation in Roc
https://www.roc-lang.org/functional#opportunistic-mutation
2
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coffeeaddict1
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34m ago
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0 comments
Online outages: Q3 2025 Internet disruption summary
https://blog.cloudflare.com/q3-2025-internet-disruption-summary/
1
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corvad
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36m ago
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0 comments
Show HN: Monitor on Your Chess Addiction
https://chess-stats.alexboden.ca/
2
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alexboden
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37m ago
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0 comments
Red Hat to Distribute Nvidia CUDA Across RHEL, Red Hat AI and OpenShift
https://www.phoronix.com/news/Red-Hat-Distribute-CUDA-RHEL
2
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ashvardanian
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37m ago
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0 comments
Ask HN: Are the tech levels now diluted post-pandemic (Google/Meta)
2
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alpb
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40m ago
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0 comments
Show HN: Sonura Studio: AI music production built for collaboration
https://sonurastudio.com/
1
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kindred
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42m ago
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0 comments
Discovering state-of-the-art reinforcement learning algorithms
https://www.nature.com/articles/s41586-025-09761-x
4
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lawrenceyan
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44m ago
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0 comments
X-59 Soars: A New Era in Supersonic Flight Begins – Oct 28, 2025
https://news.lockheedmartin.com/2025-10-28-X-59-Soars-A-New-Era-in-Supersonic-Flight-Begins
2
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bpierre
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49m ago
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0 comments
Database backups, dump files and restic
https://strugglers.net/posts/2025/database-backups-dump-files-and-restic/
3
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todsacerdoti
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51m ago
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0 comments
Pearl: A Foundation Model for Placing Every Atom in the Right Location [pdf]
https://genesis.ml/wp-content/uploads/2025/10/pearl_technical_report.pdf
4
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daedalus2718
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51m ago
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0 comments
Show HN: OXH AI – Open-Source AI Crypto Signal Platform with Real-Time Analysis
https://www.oxher.com
1
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oxhai
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59m ago
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0 comments
Show HN: Created a Live Anime Channel, no server necessary
https://animaxreboot.pages.dev/
2
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LandOfMightDev
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1h ago
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3 comments
Westinghouse is claiming a nuclear deal would see $80B of new reactors
https://arstechnica.com/science/2025/10/westinghouse-is-claiming-a-nuclear-deal-would-see-80b-of-...
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atilimcetin
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1h ago
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2 comments
AMZN Layoffs show what AI is coming for our jobs, whether its good enough or not
https://www.amazonclimatejustice.org/open-letter
2
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todchavez
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1h ago
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2 comments
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