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Show HN: Amdb – Tree-sitter based memory for AI agents (Rust)

https://github.com/BETAER-08/amdb
1•try_betaer•32s ago•0 comments

OpenClaw Partners with VirusTotal for Skill Security

https://openclaw.ai/blog/virustotal-partnership
1•anhxuan•38s ago•0 comments

Show HN: Seedance 2.0 Release

https://seedancy2.com/
1•funnycoding•1m ago•0 comments

Leisure Suit Larry's Al Lowe on model trains, funny deaths and Disney

https://spillhistorie.no/2026/02/06/interview-with-sierra-veteran-al-lowe/
1•thelok•1m ago•0 comments

Towards Self-Driving Codebases

https://cursor.com/blog/self-driving-codebases
1•edwinarbus•1m ago•0 comments

VCF West: Whirlwind Software Restoration – Guy Fedorkow [video]

https://www.youtube.com/watch?v=YLoXodz1N9A
1•stmw•2m ago•1 comments

Show HN: COGext – A minimalist, open-source system monitor for Chrome (<550KB)

https://github.com/tchoa91/cog-ext
1•tchoa91•3m ago•0 comments

FOSDEM 26 – My Hallway Track Takeaways

https://sluongng.substack.com/p/fosdem-26-my-hallway-track-takeaways
1•birdculture•3m ago•0 comments

Show HN: Env-shelf – Open-source desktop app to manage .env files

https://env-shelf.vercel.app/
1•ivanglpz•7m ago•0 comments

Show HN: Almostnode – Run Node.js, Next.js, and Express in the Browser

https://almostnode.dev/
1•PetrBrzyBrzek•7m ago•0 comments

Dell support (and hardware) is so bad, I almost sued them

https://blog.joshattic.us/posts/2026-02-07-dell-support-lawsuit
1•radeeyate•8m ago•0 comments

Project Pterodactyl: Incremental Architecture

https://www.jonmsterling.com/01K7/
1•matt_d•8m ago•0 comments

Styling: Search-Text and Other Highlight-Y Pseudo-Elements

https://css-tricks.com/how-to-style-the-new-search-text-and-other-highlight-pseudo-elements/
1•blenderob•10m ago•0 comments

Crypto firm accidentally sends $40B in Bitcoin to users

https://finance.yahoo.com/news/crypto-firm-accidentally-sends-40-055054321.html
1•CommonGuy•11m ago•0 comments

Magnetic fields can change carbon diffusion in steel

https://www.sciencedaily.com/releases/2026/01/260125083427.htm
1•fanf2•11m ago•0 comments

Fantasy football that celebrates great games

https://www.silvestar.codes/articles/ultigamemate/
1•blenderob•11m ago•0 comments

Show HN: Animalese

https://animalese.barcoloudly.com/
1•noreplica•12m ago•0 comments

StrongDM's AI team build serious software without even looking at the code

https://simonwillison.net/2026/Feb/7/software-factory/
2•simonw•12m ago•0 comments

John Haugeland on the failure of micro-worlds

https://blog.plover.com/tech/gpt/micro-worlds.html
1•blenderob•13m ago•0 comments

Show HN: Velocity - Free/Cheaper Linear Clone but with MCP for agents

https://velocity.quest
2•kevinelliott•13m ago•2 comments

Corning Invented a New Fiber-Optic Cable for AI and Landed a $6B Meta Deal [video]

https://www.youtube.com/watch?v=Y3KLbc5DlRs
1•ksec•15m ago•0 comments

Show HN: XAPIs.dev – Twitter API Alternative at 90% Lower Cost

https://xapis.dev
2•nmfccodes•15m ago•1 comments

Near-Instantly Aborting the Worst Pain Imaginable with Psychedelics

https://psychotechnology.substack.com/p/near-instantly-aborting-the-worst
2•eatitraw•21m ago•0 comments

Show HN: Nginx-defender – realtime abuse blocking for Nginx

https://github.com/Anipaleja/nginx-defender
2•anipaleja•22m ago•0 comments

The Super Sharp Blade

https://netzhansa.com/the-super-sharp-blade/
1•robin_reala•23m ago•0 comments

Smart Homes Are Terrible

https://www.theatlantic.com/ideas/2026/02/smart-homes-technology/685867/
2•tusslewake•25m ago•0 comments

What I haven't figured out

https://macwright.com/2026/01/29/what-i-havent-figured-out
1•stevekrouse•25m ago•0 comments

KPMG pressed its auditor to pass on AI cost savings

https://www.irishtimes.com/business/2026/02/06/kpmg-pressed-its-auditor-to-pass-on-ai-cost-savings/
1•cainxinth•25m ago•0 comments

Open-source Claude skill that optimizes Hinge profiles. Pretty well.

https://twitter.com/b1rdmania/status/2020155122181869666
3•birdmania•26m ago•1 comments

First Proof

https://arxiv.org/abs/2602.05192
8•samasblack•28m ago•4 comments
Open in hackernews

The three thousand year journey of colchicine

https://www.worksinprogress.news/p/the-three-thousand-year-journey-of
36•quadrin•2mo ago

Comments

CheeseFromLidl•2mo ago
I opened the article expecting to read about its use in plant breeding: colchicine is renowned there for inducing polyploidy. Never knew it has a history in medicine.

https://en.wikipedia.org/wiki/Polyploidy

34679•2mo ago
Same here. I have a bottle in my freezer for that purpose.
kubafu•2mo ago
Never heard of it, please tell me more about using it in plant breeding!
mapmeld•2mo ago
Humans have two copies of each chromosome. Plants in nature can have many more, and some can be induced to duplicate their chromosomes which sometimes gives them larger seeds and resilience to environmental conditions. Similar to hybrid crops but somehow containing the full genomes of both parents. Bread wheat is hexapoloid (containing sub-genomes from three varieties of wheat) and quinoa is tetraploid (containing two different species). There have been projects for ~100 years to make polyploid rice with heavier grain-weight, but they haven't been able to reproduce.
kubafu•2mo ago
Super interesting, thanks!
siamese_puff•2mo ago
After seeing multiple doctors in the USA (where I no longer live thankfully) for a chronic mouth ulcer problem an allergist prescribed me colchicine which seemed to cure them. These ulcers lasted over 15 years and colchicine seemed to be the only thing to eradicate them.

Insurance wouldn’t cover the cost and colchicine cost me $500 a month for a bottle. In the UK I can pay 10 pounds. Crazy drug and crazy price for something 3000 years old

readthenotes1•2mo ago
Someone has to pay for the regulatory studies. Someone has to pay for purity. Someone has to pay for marketing, legal, and other corporate overhead.

My understanding is that for drugs with FDA approval, almost all that cost burden has historically been borne by customers in the USA.

Oh, and profit. Ditto

vad1d3v•2mo ago
colchicine is a life safer for me with gouty went rough on of me! 3000 years of poison!! I'd have never imagine that.