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There may not be a safe off-ramp for some taking GLP-1 drugs, study suggests

https://arstechnica.com/health/2025/11/glp-1-drugs-improve-heart-health-but-only-if-you-keep-taking-them/
1•voxadam•8m ago

AI Trained on Bacterial Genomes

https://arstechnica.com/science/2025/11/generative-ai-meets-the-genome/
1•I_Nidhi•1m ago•0 comments

Completing, Integrating, and Publishing Our Game with DragonRuby

https://blog.appsignal.com/2025/11/26/completing-integrating-and-publishing-our-game-with-dragonr...
1•amalinovic•2m ago•0 comments

Show HN: Automated Defense for Automated Offense

1•duane_powers•3m ago•0 comments

Ask HN: GitHub SN

1•caliweed•4m ago•0 comments

KDE going all-in on a Wayland future

https://blogs.kde.org/2025/11/26/going-all-in-on-a-wayland-future/
1•todsacerdoti•7m ago•0 comments

There may not be a safe off-ramp for some taking GLP-1 drugs, study suggests

https://arstechnica.com/health/2025/11/glp-1-drugs-improve-heart-health-but-only-if-you-keep-taki...
1•voxadam•8m ago•0 comments

Sophie – Senior Back end Engineer – London (Hybrid, 2 days/week) – Full-time

https://app.welcometothejungle.com/jobs/zgdcjy1T
1•juliosophiedoc•8m ago•1 comments

Traders Are Flooding Markets with Risky Bets. Robinhood's CEO Is Their Cult Hero

https://www.wsj.com/finance/robinhood-ceo-vlad-tenev-04e3ab28
1•thm•9m ago•0 comments

Dyalog v20.0 is now available for everyone

https://www.dyalog.com/dyalog/dyalog-versions/200.htm
1•pillowshift•11m ago•0 comments

Video Reveals How Far Wolves Will Go to Steal a Meal

https://www.nytimes.com/2025/11/17/science/wolf-tool-use-steal-food.html
1•bookofjoe•15m ago•1 comments

Burt Meyer, Inventor of Rock 'Em Sock 'Em Robots and Other Hit Toys, Dies at 99

https://www.wsj.com/business/retail/burt-meyer-toy-inventor-dead-674a37e2
1•fortran77•15m ago•1 comments

ESP32

https://en.wikipedia.org/wiki/ESP32
2•doener•16m ago•0 comments

HP Inc. Reports Fiscal 2025 Full Year and Fourth Quarter Results [pdf]

https://s203.q4cdn.com/918857832/files/doc_financials/2025/q4/Q425_HP-Inc-Earnings-Press-Release.pdf
1•doener•17m ago•0 comments

Metaphysical Priming reduces Gemini 3.0 Pro inference latency by 60%

https://github.com/Cactus-mp4/DATtest_Gemini3.0Pro_BenevolentJailbreak
1•cactus-jpg•19m ago•1 comments

TSMC sues former executive over defection to Intel

https://www.tomshardware.com/tech-industry/semiconductors/tsmc-sues-former-executive-over-defecti...
1•zvr•20m ago•0 comments

FileBrowser Quantum: The best free self-hosted web-based file manager

https://github.com/gtsteffaniak/filebrowser
1•thunderbong•21m ago•0 comments

Fire-blocking chemicals promise safer buildings

https://www.bbc.com/news/articles/ckgkee0pw4ko
1•ksec•21m ago•0 comments

The tech debt elephant: A product perspective

https://www.hyperact.co.uk/blog/tech-debt-a-product-perspective
1•birdculture•22m ago•0 comments

A Government Think Tank Trained the First Generation of US Software Developers

https://www.construction-physics.com/p/how-a-government-think-tank-trained
2•chmaynard•23m ago•0 comments

Show HN: Nasdaq ITCH parser that processes 107M messages/SEC

https://lunyn.com/blog/itch-parser-107m/
1•sundancegh•24m ago•1 comments

Voyager 1 Is About to Reach One Light-Day from Earth

https://scienceclock.com/voyager-1-is-about-to-reach-one-light-day-from-earth/
3•ashishgupta2209•27m ago•0 comments

Ask HN: Best learning path to build real apps with AI tools in 2025?

2•adilmoujahid•27m ago•0 comments

Loss.md

https://tech.lgbt/@graeme/115608824482129660
1•graemefawcett•29m ago•0 comments

Kraken's Standard App Charges Up to 14x More in Fees Than Kraken Pro

https://www.crypto-news.net/kraken-fees-instant-buy-vs-pro-comparison-2025/
2•zoransp•29m ago•1 comments

Show HN: Claude Opus 4.5 plays League of Legends

https://github.com/pravaco/cuaview-releases/tree/v0.2.0
1•sdan•30m ago•0 comments

Robinhood, Susquehanna Escalate Prediction-Market Arms Race

https://www.bloomberg.com/news/articles/2025-11-26/miax-sells-ledgerx-exchange-once-owned-by-ftx-...
2•noitpmeder•30m ago•1 comments

Topological turning points across the human lifespan

https://www.nature.com/articles/s41467-025-65974-8
1•gmays•30m ago•0 comments

Mean Time Between Failures

https://netwars.pelicancrossing.net/2025/11/21/mean-time-between-failure/
1•ColinWright•32m ago•0 comments

Microsoft Signing Transparency: Secure Software Supply Chains

https://azure.microsoft.com/en-us/blog/enhancing-software-supply-chain-security-with-microsofts-s...
2•speckx•32m ago•0 comments

Create and host a telegram bot with go

https://docs.codecapsules.io/tutorials/create-and-host-go-ai-telegram-bot
2•ritzaco•33m ago•0 comments