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The next frontier in weight-loss drugs: one-time gene therapy

https://www.washingtonpost.com/health/2026/01/24/fractyl-glp1-gene-therapy/
1•bookofjoe•2m ago•1 comments

At Age 25, Wikipedia Refuses to Evolve

https://spectrum.ieee.org/wikipedia-at-25
1•asdefghyk•5m ago•2 comments

Show HN: ReviewReact – AI review responses inside Google Maps ($19/mo)

https://reviewreact.com
1•sara_builds•6m ago•0 comments

Why AlphaTensor Failed at 3x3 Matrix Multiplication: The Anchor Barrier

https://zenodo.org/records/18514533
1•DarenWatson•7m ago•0 comments

Ask HN: How much of your token use is fixing the bugs Claude Code causes?

1•laurex•10m ago•0 comments

Show HN: Agents – Sync MCP Configs Across Claude, Cursor, Codex Automatically

https://github.com/amtiYo/agents
1•amtiyo•11m ago•0 comments

Hello

1•otrebladih•12m ago•0 comments

FSD helped save my father's life during a heart attack

https://twitter.com/JJackBrandt/status/2019852423980875794
2•blacktulip•15m ago•0 comments

Show HN: Writtte – Draft and publish articles without reformatting, anywhere

https://writtte.xyz
1•lasgawe•17m ago•0 comments

Portuguese icon (FROM A CAN) makes a simple meal (Canned Fish Files) [video]

https://www.youtube.com/watch?v=e9FUdOfp8ME
1•zeristor•19m ago•0 comments

Brookhaven Lab's RHIC Concludes 25-Year Run with Final Collisions

https://www.hpcwire.com/off-the-wire/brookhaven-labs-rhic-concludes-25-year-run-with-final-collis...
2•gnufx•21m ago•0 comments

Transcribe your aunts post cards with Gemini 3 Pro

https://leserli.ch/ocr/
1•nielstron•25m ago•0 comments

.72% Variance Lance

1•mav5431•26m ago•0 comments

ReKindle – web-based operating system designed specifically for E-ink devices

https://rekindle.ink
1•JSLegendDev•27m ago•0 comments

Encrypt It

https://encryptitalready.org/
1•u1hcw9nx•27m ago•1 comments

NextMatch – 5-minute video speed dating to reduce ghosting

https://nextmatchdating.netlify.app/
1•Halinani8•28m ago•1 comments

Personalizing esketamine treatment in TRD and TRBD

https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1736114
1•PaulHoule•30m ago•0 comments

SpaceKit.xyz – a browser‑native VM for decentralized compute

https://spacekit.xyz
1•astorrivera•30m ago•0 comments

NotebookLM: The AI that only learns from you

https://byandrev.dev/en/blog/what-is-notebooklm
2•byandrev•31m ago•1 comments

Show HN: An open-source starter kit for developing with Postgres and ClickHouse

https://github.com/ClickHouse/postgres-clickhouse-stack
1•saisrirampur•31m ago•0 comments

Game Boy Advance d-pad capacitor measurements

https://gekkio.fi/blog/2026/game-boy-advance-d-pad-capacitor-measurements/
1•todsacerdoti•32m ago•0 comments

South Korean crypto firm accidentally sends $44B in bitcoins to users

https://www.reuters.com/world/asia-pacific/crypto-firm-accidentally-sends-44-billion-bitcoins-use...
2•layer8•32m ago•0 comments

Apache Poison Fountain

https://gist.github.com/jwakely/a511a5cab5eb36d088ecd1659fcee1d5
1•atomic128•34m ago•2 comments

Web.whatsapp.com appears to be having issues syncing and sending messages

http://web.whatsapp.com
1•sabujp•35m ago•2 comments

Google in Your Terminal

https://gogcli.sh/
1•johlo•36m ago•0 comments

Shannon: Claude Code for Pen Testing: #1 on Github today

https://github.com/KeygraphHQ/shannon
1•hendler•36m ago•0 comments

Anthropic: Latest Claude model finds more than 500 vulnerabilities

https://www.scworld.com/news/anthropic-latest-claude-model-finds-more-than-500-vulnerabilities
2•Bender•41m ago•0 comments

Brooklyn cemetery plans human composting option, stirring interest and debate

https://www.cbsnews.com/newyork/news/brooklyn-green-wood-cemetery-human-composting/
1•geox•41m ago•0 comments

Why the 'Strivers' Are Right

https://greyenlightenment.com/2026/02/03/the-strivers-were-right-all-along/
1•paulpauper•42m ago•0 comments

Brain Dumps as a Literary Form

https://davegriffith.substack.com/p/brain-dumps-as-a-literary-form
1•gmays•43m ago•0 comments
Open in hackernews

AWS introduces Graviton5–the company's most powerful and efficient CPU

https://www.aboutamazon.com/news/aws/aws-graviton-5-cpu-amazon-ec2
31•ksec•2mo ago

Comments

spwa4•2mo ago
Wouldn't the business impact always be performance per dollar from client perspective? This reads like a document that's meant to convince AWS management to invest in the new chip, focusing on how it's maximally flexible for sale, not a document to convince customers to use it ...
dpoloncsak•2mo ago
It's an advertisement to investors that they have a new product that's better than their last
spwa4•2mo ago
Ah I see. What has the world gotten to? (by which I mean businesses should not advertise to raise their stock price)
dpoloncsak•2mo ago
How else do you fulfill your fiduciary duty to shareholders?
DonHopkins•1mo ago
Tweet lies to manipulate the stock, like Elon Musk.
locknitpicker•1mo ago
> This reads like a document that's meant to convince AWS management to invest in the new chip, focusing on how it's maximally flexible for sale, not a document to convince customers to use it ...

AWS management is the customer.

Higher compute density, lower infrastructure costs, and higher performance. Those are data center selling points.

The truth of the matter is that your average external customer doesn't really care about CPU architectures if all they are doing is using serverless offerings, specially AWS Lambdas handling events. They care about what it costs them to run the services. AWS management decide if the returns on their investment is paying off and helps them lower costs and improve margins.

rtp4me•2mo ago
Can someone please confirm, is the Graviton an ARM-based CPU or something different? The page mentioned ARM, but I was still a little confused. Are we able to launch a Debian/Fedora using the CPU, or is meant for something different?
butvacuum•2mo ago
Yes, the gravatons are the AWS arm architecture instances
rtp4me•2mo ago
Thanks, so "standard" ARM we can launch VMs with? I wasn't sure if this was some sort of proprietary ARM chip use for specialized work.
quesomaster9000•2mo ago
Yup, Amazon supports the 6.11? kernel on aarch64. Most toolchains if you target linux aarch64 static they, they will produce executables that will run on Amazon Linux aarch64 and Android, set-top boxes with 64-bit chips and Linux 3+ it's surprising how many devices a static aarch64 ELF will run on.
rtp4me•2mo ago
Awesome, thanks for this. Off to build new Ansible deployment scripts for aarch64!
butvacuum•2mo ago
As far as I'm aware- if it's called an ARM CPU it's either the v7 or v8 instruction set with the possibility of extra instructions (changes to ARM die) or a tightly integrated coprocessor (via AXI bus, adjacent to the ARM silicon on the same substrate).

There are different Coretex series that optimize for different things- A and X for applications (phones, cloud compute, SBCs, desktops and laptops), M for microcontrollers, and R for realtime.

This doesn't apply if the company has an ARM founder and/or architecture license. (I think that's what they're called) Eg- Apple and their M series SOCs are not Coretex cores, but share the base instruction set- but only if Apple wants it to.

everfrustrated•2mo ago
Yes, think AMD vs Intel. Same x86 target but built differently under the hood with potential to optimize for certain uses over others.
crest•1mo ago
It's based on ARM Neoverse V3 cores which are very similar to the latest high performance mobile Cortex X4 cores.
quesomaster9000•2mo ago
Graviton with Nitro 4 has been quite pleasant to use, with the rust aarch64 musl static target and rust-lld I can build monolith ELFs that work not just on my android via `adb push` and `adb shell` but also on AWS.

AWS with Nitro v3+ iirc supports TPM, meaning I can attest my VM state via an Amazon CA. I know ARM has been working a lot with Rust, and it shows - binfmt with qemu-user mean I often forget which architecture I'm building/running/testing as the binaries seem to work the same everywhere.

nodesocket•2mo ago
Are they updating the t class instances to t5g as well?
jng•1mo ago
They usually end up upgrading most instance types to new graviton generations, it just takes time to do the full rollout.
MrDOS•1mo ago
Not really: burstable (“t”) instances haven't been updated in years. The current generation (“t4g”) still use Graviton2 processors. I get the impression that they would vastly prefer cost-conscious users to use spot instances.
everfrustrated•1mo ago
the -flex suffix variants seem to be the new spiritual successor to the t burstable class.

eg c7i-flex.large, etc.

hulitu•2mo ago
> With 192 cores per chip

Just like AMD Epyc.

> and 5x larger cache,

Larger than what ? 16k ?

crest•1mo ago
Larger than the same cache level on its predecessor (the Graviton4).