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Ask HN: Which whole genome sequencing provider do you recommend in 2025?

1•croemer•2h ago
I work in bioinformatics and am interested in learning more about human genome analyses. Naturally, it's most fun to look into your own genome for concreteness.

Has anyone done WGS and has some insights to share?

I'm thinking of ordering under a pseudonym to make deanonymzing just a little harder.

Show HN: Free tool to blur images instantly without signup or watermarks

https://www.blurimageonline.com/
1•teroquyiqwu•1m ago•0 comments

Against Likes and Subscribers

https://metanomad.blog/against-likes-and-subscribers/
1•speckx•3m ago•0 comments

Inception X TicTacToe: a fractal game

https://tic-tac-toe-inception-49280791970.us-west1.run.app/
1•apitaru•5m ago•1 comments

An 11-qubit atom processor in silicon with all fidelities from 99.10% to 99.99%

https://www.nature.com/articles/s41586-025-09827-w
1•giuliomagnifico•5m ago•0 comments

Eye Sentry: 5-Day Built macOS Eye Care Tool

https://eye-sentry.vercel.app
1•lispking•7m ago•1 comments

Language Switcher Guide: Java, JavaScript, Python, Go Comparison for B

https://blog.blockingqueue.com/language-switcher-cheatsheet-java-javascript-python-go
1•liviu31•7m ago•0 comments

Research Reveals the Optimal Way to Optimize

https://www.wired.com/story/researchers-discover-the-optimal-way-to-optimize/
2•quapster•8m ago•0 comments

NY Gov. vetoes bill to mandate 2-person subway train crews

https://gothamist.com/news/ny-gov-hochul-vetoes-bill-to-mandate-2-person-subway-train-crews
1•geox•9m ago•0 comments

A Homebuilt CO2 Meter as a Virus Risk Proxy (Shallow Thoughts)

https://shallowsky.com/blog/hardware/co2-meter.html
1•speckx•15m ago•0 comments

Stop Saying "Agent" – Name the Work, Own the Output

https://btriani.medium.com/stop-saying-agent-name-the-work-own-the-output-a9a2902a5314
1•btriani•15m ago•0 comments

Mnemonics for Hidden Controls in Win32

https://www.abareplace.com/blog/hidden_mnemonics/
1•todsacerdoti•19m ago•0 comments

Loud Rabbit (Music Video / Lyrics)

https://www.tolmix.com/loud-rabbit
1•n-fuselius•19m ago•1 comments

Show HN: Lockify – developer-friendly CLI for managing encrypted env variables

https://github.com/ahmed-abdelgawad92/lockify
2•ahmedabdelgawad•20m ago•0 comments

Lightweight is a metric, not an adjective

https://simpleobservability.com/blog/lightweight-is-metric
1•khazit•31m ago•0 comments

12 days on Wolf Rock Lighthouse [video]

https://www.youtube.com/watch?v=PhRbJ3DQdlQ
1•bschne•33m ago•0 comments

Jingle Bells (Batman Smells): an incomplete festive folk-rhyme taxonomy

https://loreandordure.com/2025/12/16/jingle-bells/
2•helsinkiandrew•34m ago•0 comments

Yann LeCun Is Raising Half a Billion Dollars to Build Nothing (Yet)

https://medium.com/@anwarzaid76/yann-lecun-is-raising-half-a-billion-dollars-to-build-nothing-yet...
2•MindBreaker2605•36m ago•0 comments

No Fun Allowed

https://josevalerio.com/no-fun-allowed
1•josevalerio•40m ago•0 comments

Show HN: Zimage2.online – An AI image tool built on Alibaba's Z-Image model

https://zimage2.online/
1•chenliang001•42m ago•0 comments

The ML Trench

https://deep-ml-trench.vercel.app/
1•hexhowells•42m ago•0 comments

The iPhone 16e Is Good

https://manualdousuario.net/en/iphone-16e-is-good-actually/
1•rpgbr•43m ago•0 comments

AI in 2026 and beyond ⊗ Bioregionalism's tech-driven revival

https://sentiers.media/ai-in-2026-and-beyond-bioregionalisms-tech-driven-revival-no-384/
1•speckx•44m ago•0 comments

Show HN: Dots: a bullet journal I built to understand my migraines

https://dotsjournal.app/
1•tubignaaso•46m ago•0 comments

US submarines are outnumbered in the Pacific. South Korea has a plan to help

https://www.cnn.com/2025/12/20/asia/south-korea-nuclear-powered-submarines-intl-hnk-ml-dst
1•breve•46m ago•0 comments

Construct in 2025: Year in Review

https://www.construct.net/en/blogs/construct-official-blog-1/construct-2025-year-review-1898
1•AshleysBrain•50m ago•0 comments

Teardown of the Gigaset CL660HX DECT phone and how to disable annoying flash LED

https://github.com/hn/gigaset-cl660hx
2•hn___•52m ago•0 comments

New mathematical framework reshapes debate over simulation hypothesis

https://www.santafe.edu/news-center/news/new-mathematical-framework-reshapes-debate-over-simulati...
10•Gooblebrai•52m ago•1 comments

Show HN: Pilotbook.pro – born from spending more time on paperwork than flying

https://pilotbook.pro/
1•j4nitor•53m ago•0 comments

A Knapsack Public Key Cryptosystem Based on Arithmetic in Finite Fields (1988) [pdf]

https://people.csail.mit.edu/rivest/pubs/CR88.pdf
1•keepamovin•55m ago•0 comments

Google Cloud Infrastructure 2025: The Year Kubernetes Got Boring

https://www.aimeemarieknight.com/Google-Cloud-Infrastructure-2025-The-Year-Kubernetes-Got-Boring/
1•speckx•56m ago•0 comments