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KV Cache Transform Coding for Compact Storage in LLM Inference

https://arxiv.org/abs/2511.01815
1•walterbell•33s ago•0 comments

A quantitative, multimodal wearable bioelectronic device for stress assessment

https://www.nature.com/articles/s41467-025-67747-9
1•PaulHoule•2m ago•0 comments

Why Big Tech Is Throwing Cash into India in Quest for AI Supremacy

https://www.wsj.com/world/india/why-big-tech-is-throwing-cash-into-india-in-quest-for-ai-supremac...
1•saikatsg•2m ago•0 comments

How to shoot yourself in the foot – 2026 edition

https://github.com/aweussom/HowToShootYourselfInTheFoot
1•aweussom•2m ago•0 comments

Eight More Months of Agents

https://crawshaw.io/blog/eight-more-months-of-agents
2•archb•4m ago•0 comments

From Human Thought to Machine Coordination

https://www.psychologytoday.com/us/blog/the-digital-self/202602/from-human-thought-to-machine-coo...
1•walterbell•5m ago•0 comments

The new X API pricing must be a joke

https://developer.x.com/
1•danver0•6m ago•0 comments

Show HN: RMA Dashboard fast SAST results for monorepos (SARIF and triage)

https://rma-dashboard.bukhari-kibuka7.workers.dev/
1•bumahkib7•6m ago•0 comments

Show HN: Source code graphRAG for Java/Kotlin development based on jQAssistant

https://github.com/2015xli/jqassistant-graph-rag
1•artigent•11m ago•0 comments

Python Only Has One Real Competitor

https://mccue.dev/pages/2-6-26-python-competitor
3•dragandj•13m ago•0 comments

Tmux to Zellij (and Back)

https://www.mauriciopoppe.com/notes/tmux-to-zellij/
1•maurizzzio•13m ago•1 comments

Ask HN: How are you using specialized agents to accelerate your work?

1•otterley•15m ago•0 comments

Passing user_id through 6 services? OTel Baggage fixes this

https://signoz.io/blog/otel-baggage/
1•pranay01•15m ago•0 comments

DavMail Pop/IMAP/SMTP/Caldav/Carddav/LDAP Exchange Gateway

https://davmail.sourceforge.net/
1•todsacerdoti•16m ago•0 comments

Visual data modelling in the browser (open source)

https://github.com/sqlmodel/sqlmodel
1•Sean766•18m ago•0 comments

Show HN: Tharos – CLI to find and autofix security bugs using local LLMs

https://github.com/chinonsochikelue/tharos
1•fluantix•19m ago•0 comments

Oddly Simple GUI Programs

https://simonsafar.com/2024/win32_lights/
1•MaximilianEmel•19m ago•0 comments

The New Playbook for Leaders [pdf]

https://www.ibli.com/IBLI%20OnePagers%20The%20Plays%20Summarized.pdf
1•mooreds•19m ago•0 comments

Interactive Unboxing of J Dilla's Donuts

https://donuts20.vercel.app
1•sngahane•21m ago•0 comments

OneCourt helps blind and low-vision fans to track Super Bowl live

https://www.dezeen.com/2026/02/06/onecourt-tactile-device-super-bowl-blind-low-vision-fans/
1•gaws•22m ago•0 comments

Rudolf Vrba

https://en.wikipedia.org/wiki/Rudolf_Vrba
1•mooreds•23m ago•0 comments

Autism Incidence in Girls and Boys May Be Nearly Equal, Study Suggests

https://www.medpagetoday.com/neurology/autism/119747
1•paulpauper•24m ago•0 comments

Wellness Hotels Discovery Application

https://aurio.place/
1•cherrylinedev•25m ago•1 comments

NASA delays moon rocket launch by a month after fuel leaks during test

https://www.theguardian.com/science/2026/feb/03/nasa-delays-moon-rocket-launch-month-fuel-leaks-a...
1•mooreds•25m ago•0 comments

Sebastian Galiani on the Marginal Revolution

https://marginalrevolution.com/marginalrevolution/2026/02/sebastian-galiani-on-the-marginal-revol...
2•paulpauper•28m ago•0 comments

Ask HN: Are we at the point where software can improve itself?

1•ManuelKiessling•29m ago•2 comments

Binance Gives Trump Family's Crypto Firm a Leg Up

https://www.nytimes.com/2026/02/07/business/binance-trump-crypto.html
1•paulpauper•29m ago•1 comments

Reverse engineering Chinese 'shit-program' for absolute glory: R/ClaudeCode

https://old.reddit.com/r/ClaudeCode/comments/1qy5l0n/reverse_engineering_chinese_shitprogram_for/
1•edward•29m ago•0 comments

Indian Culture

https://indianculture.gov.in/
1•saikatsg•32m ago•0 comments

Show HN: Maravel-Framework 10.61 prevents circular dependency

https://marius-ciclistu.medium.com/maravel-framework-10-61-0-prevents-circular-dependency-cdb5d25...
1•marius-ciclistu•32m ago•0 comments
Open in hackernews

Older Americans quit weight loss drugs in droves

https://www.seattletimes.com/nation-world/older-americans-quit-weight-loss-drugs-in-droves/
14•paulpauper•1mo ago

Comments

AndrewKemendo•1mo ago
I thought it would take a decade for the side effects to catch up with people but this is way faster than expected.

There are no shortcuts to holistic health.

In a sick and corrupt environment the worn path is harmful by default.

djohnston•1mo ago
> There are no shortcuts to holistic health.

I agree with that.

> I thought it would take a decade for the side effects to catch up with people but this is way faster than expected.

Regarding the side effects, nothing seemed beyond the realm of what you'd read on the outside of an OTC cold medication. I'm not a doctor but they don't seem that severe.

AndrewKemendo•1mo ago
I suggest you go back and read the article to see the difference between realized effects and the stated effects.

Are you credulous to what product and drug producers post on a label? Why would you ever believe that?

toomuchtodo•1mo ago
The elderly are simply not as tolerant of the side effects. It still works fine in younger cohorts who can manage with potential side effects. This means the criteria for use in the elderly needs to be modified so they aren’t force fed this pharma intervention for revenue optimization.

(both my partner and I, early 40s, are on a GLP-1, with no side effects; we’ve each lost ~40lbs in 4-5 months)

AndrewKemendo•1mo ago
We heard the EXACT same from phenphen users too in the 90s. My friend was the litigator for the class action.

There’s no biologically free way to lose weight that quickly without massive downstream effects, SOMETHING is going to eventually come out like it always does.

The fact that people are making conclusions with less than 5 years of evidence is why we’re always screwed.

https://en.wikipedia.org/wiki/Fenfluramine/phentermine

toomuchtodo•1mo ago
And I can provide examples of Metformin being very safe with the exception of a few edge cases, while providing exceptional benefit across a wide cross section of the population. Could something exceptional crop up? Potentially. But so far, the data is very compelling GLP-1RAs have a reasonable safety profile for the enormous benefit provided.

https://intermountainhealthcare.org/blogs/article/your-frien...

> Are GLP-1s safe? What are the side effects? > GLP-1s have been extensively studied and are considered safe when prescribed and monitored by a healthcare provider.

With all of this said, I'm open to having a mutually agreed upon subject matter expert provide the equivalent of an opinion letter on the safety of GLP-1RAs at my (reasonable and customary) cost. Feel free to propose one.

solumunus•1mo ago
These drugs have an incredible effect to side effect ratio. Most people sincerely taking them are in far better health with them than without.
Centigonal•1mo ago
This article showcases multiple causes for why seniors are coming off of these drugs: drug shortages, changing insurance coverage, muscle loss, and other side effects are all included. Let's not be too hasty when attributing cause to this trend.
MarkusQ•1mo ago
Why highlight seniors then? The same factors apply to younger patients. The only explanation that makes sense is that "seniors" is a valuable ad word for the market this clickbait gibberish (or rather, "tossed factoid salad") targets.
SR2Z•1mo ago
Seniors are almost all on Medicare and have obesity-related health issues more frequently than young people.
MarkusQ•1mo ago
> Medicare covered it for treating Type 2 diabetes but not for weight loss

> [...] to Bucklew’s surprise, her Medicare Advantage plan covered it even

> though she wasn’t diabetic, charging just a $25 monthly copay.

> [...] Then her Medicare plan notified her that it would no longer cover

> the drug [...] With coverage denied, Bucklew became part of an unsettlingly

> large group: older adults who begin taking GLP-1s and related drugs [...] and

> then stop taking them within months.

This feels like it's really straining the facts to jam them into a narrative, then mostly fails to construct one. Is it an article about drug side effects? Insurance fraud? Health benefits of GLP-1s? Medicare policy?

Strangely, it feels like something that would actually have been more coherent if it had been written by an LLM.