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Learning to code, or building side projects with AI help, this one's for you

https://codeslick.dev/learn
1•vitorlourenco•29s ago•0 comments

Effulgence RPG Engine [video]

https://www.youtube.com/watch?v=xFQOUe9S7dU
1•msuniverse2026•1m ago•0 comments

Five disciplines discovered the same math independently – none of them knew

https://freethemath.org
1•energyscholar•2m ago•1 comments

We Scanned an AI Assistant for Security Issues: 12,465 Vulnerabilities

https://codeslick.dev/blog/openclaw-security-audit
1•vitorlourenco•3m ago•0 comments

Amazon no longer defend cloud customers against video patent infringement claims

https://ipfray.com/amazon-no-longer-defends-cloud-customers-against-video-patent-infringement-cla...
1•ffworld•3m ago•0 comments

Show HN: Medinilla – an OCPP compliant .NET back end (partially done)

https://github.com/eliodecolli/Medinilla
2•rhcm•6m ago•0 comments

How Does AI Distribute the Pie? Large Language Models and the Ultimatum Game

https://papers.ssrn.com/sol3/papers.cfm?abstract_id=6157066
1•dkga•7m ago•1 comments

Resistance Infrastructure

https://www.profgalloway.com/resistance-infrastructure/
2•samizdis•11m ago•0 comments

Fire-juggling unicyclist caught performing on crossing

https://news.sky.com/story/fire-juggling-unicyclist-caught-performing-on-crossing-13504459
1•austinallegro•12m ago•0 comments

Restoring a lost 1981 Unix roguelike (protoHack) and preserving Hack 1.0.3

https://github.com/Critlist/protoHack
2•Critlist•13m ago•0 comments

GPS and Time Dilation – Special and General Relativity

https://philosophersview.com/gps-and-time-dilation/
1•mistyvales•17m ago•0 comments

Show HN: Witnessd – Prove human authorship via hardware-bound jitter seals

https://github.com/writerslogic/witnessd
1•davidcondrey•17m ago•1 comments

Show HN: I built a clawdbot that texts like your crush

https://14.israelfirew.co
2•IsruAlpha•19m ago•2 comments

Scientists reverse Alzheimer's in mice and restore memory (2025)

https://www.sciencedaily.com/releases/2025/12/251224032354.htm
1•walterbell•22m ago•0 comments

Compiling Prolog to Forth [pdf]

https://vfxforth.com/flag/jfar/vol4/no4/article4.pdf
1•todsacerdoti•23m ago•0 comments

Show HN: Cymatica – an experimental, meditative audiovisual app

https://apps.apple.com/us/app/cymatica-sounds-visualizer/id6748863721
1•_august•24m ago•0 comments

GitBlack: Tracing America's Foundation

https://gitblack.vercel.app/
2•martialg•24m ago•0 comments

Horizon-LM: A RAM-Centric Architecture for LLM Training

https://arxiv.org/abs/2602.04816
1•chrsw•25m ago•0 comments

We just ordered shawarma and fries from Cursor [video]

https://www.youtube.com/shorts/WALQOiugbWc
1•jeffreyjin•26m ago•1 comments

Correctio

https://rhetoric.byu.edu/Figures/C/correctio.htm
1•grantpitt•26m ago•0 comments

Trying to make an Automated Ecologist: A first pass through the Biotime dataset

https://chillphysicsenjoyer.substack.com/p/trying-to-make-an-automated-ecologist
1•crescit_eundo•30m ago•0 comments

Watch Ukraine's Minigun-Firing, Drone-Hunting Turboprop in Action

https://www.twz.com/air/watch-ukraines-minigun-firing-drone-hunting-turboprop-in-action
1•breve•31m ago•0 comments

Free Trial: AI Interviewer

https://ai-interviewer.nuvoice.ai/
1•sijain2•31m ago•0 comments

FDA intends to take action against non-FDA-approved GLP-1 drugs

https://www.fda.gov/news-events/press-announcements/fda-intends-take-action-against-non-fda-appro...
21•randycupertino•32m ago•13 comments

Supernote e-ink devices for writing like paper

https://supernote.eu/choose-your-product/
3•janandonly•35m ago•0 comments

We are QA Engineers now

https://serce.me/posts/2026-02-05-we-are-qa-engineers-now
1•SerCe•35m ago•0 comments

Show HN: Measuring how AI agent teams improve issue resolution on SWE-Verified

https://arxiv.org/abs/2602.01465
2•NBenkovich•35m ago•0 comments

Adversarial Reasoning: Multiagent World Models for Closing the Simulation Gap

https://www.latent.space/p/adversarial-reasoning
1•swyx•36m ago•0 comments

Show HN: Poddley.com – Follow people, not podcasts

https://poddley.com/guests/ana-kasparian/episodes
1•onesandofgrain•44m ago•0 comments

Layoffs Surge 118% in January – The Highest Since 2009

https://www.cnbc.com/2026/02/05/layoff-and-hiring-announcements-hit-their-worst-january-levels-si...
13•karakoram•44m ago•0 comments
Open in hackernews

Calorie Restriction Attenuates Aging Signatures in White Matter Oligodendrocytes

https://onlinelibrary.wiley.com/doi/10.1111/acel.70298
14•PaulHoule•1mo ago

Comments

CAPSLOCKSSTUCK•1mo ago
I didn't read the whole article, but what does a lifelong 30% calorie restriction mean in practice?
adrian_b•1mo ago
A long term calorie restriction that is so great has a few beneficial effects, i.e. a lower risk of cancer and a good probability of a longer life, but only if you live in very sheltered conditions, e.g. when being a lab rat or mouse or when having servants who would do everything for you.

However there are significant undesirable effects, caused by a reduced muscular mass and adipose tissue. You would become one of the weak and frail old people, who easily fall and break some limb. The resistance to any infectious diseases is also likely to be very weak.

Unfortunately, many choices that you could do about your lifestyle have both advantages and disadvantages, so it may be difficult or impossible to find an optimum. Few decisions are simple, like the decision that smoking is bad.

Someone with a sedentary lifestyle would need to eat around 1200 to 1300 kcal daily to achieve such a calorie restriction, e.g. 2 meals per day of around 600 kcal each. Of this amount of calories per day, around 400 kcal should come from protein, around 350 kcal from fat and around 450 to 550 kcal from starch. It is feasible, but it may be difficult to not be hungry between meals. Sweets would have to be mostly excluded, as they would prevent satiety and they would cause hunger soon after a meal. Protein would have to be provided mostly by pure sources, e.g. chicken/turkey breast, gelatin or protein powders, to avoid extra calories.

Most people severely underestimate their ability to become accustomed to eating much less than they currently eat, but even so I am doubtful that it is possible to enjoy eating so little as required by a lifelong 30% calorie restriction.

PaulHoule•1mo ago
I used to hang out in forums with Roy Walford's followers

https://www.amazon.com/120-Year-Diet-Double-Vital/dp/0671466...

Those folks were disdainful of "one-mouse experiments" but Roy was vital and productive for a long time and passed at 79 from ALS which is one of the worse ways you can go and used a lot of weed

https://en.wikipedia.org/wiki/Roy_Walford

I can say that when I was lowballing my calories I was often uncomfortable, particularly in the cold. If I could keep the temperature constant it might not be so hard but in an old farmhouse in NY it's pretty hard even if you are strategic about long underwear and other warm programming. But yeah, the average American could use to eat a bit less and so I could I.