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Show HN: HypothesisHub – An open API where AI agents collaborate on medical res

https://medresearch-ai.org/hypotheses-hub/
1•panossk•1m ago•0 comments

Big Tech vs. OpenClaw

https://www.jakequist.com/thoughts/big-tech-vs-openclaw/
1•headalgorithm•4m ago•0 comments

Anofox Forecast

https://anofox.com/docs/forecast/
1•marklit•4m ago•0 comments

Ask HN: How do you figure out where data lives across 100 microservices?

1•doodledood•4m ago•0 comments

Motus: A Unified Latent Action World Model

https://arxiv.org/abs/2512.13030
1•mnming•4m ago•0 comments

Rotten Tomatoes Desperately Claims 'Impossible' Rating for 'Melania' Is Real

https://www.thedailybeast.com/obsessed/rotten-tomatoes-desperately-claims-impossible-rating-for-m...
1•juujian•6m ago•0 comments

The protein denitrosylase SCoR2 regulates lipogenesis and fat storage [pdf]

https://www.science.org/doi/10.1126/scisignal.adv0660
1•thunderbong•8m ago•0 comments

Los Alamos Primer

https://blog.szczepan.org/blog/los-alamos-primer/
1•alkyon•10m ago•0 comments

NewASM Virtual Machine

https://github.com/bracesoftware/newasm
1•DEntisT_•12m ago•0 comments

Terminal-Bench 2.0 Leaderboard

https://www.tbench.ai/leaderboard/terminal-bench/2.0
2•tosh•13m ago•0 comments

I vibe coded a BBS bank with a real working ledger

https://mini-ledger.exe.xyz/
1•simonvc•13m ago•1 comments

The Path to Mojo 1.0

https://www.modular.com/blog/the-path-to-mojo-1-0
1•tosh•16m ago•0 comments

Show HN: I'm 75, building an OSS Virtual Protest Protocol for digital activism

https://github.com/voice-of-japan/Virtual-Protest-Protocol/blob/main/README.md
4•sakanakana00•19m ago•0 comments

Show HN: I built Divvy to split restaurant bills from a photo

https://divvyai.app/
3•pieterdy•21m ago•0 comments

Hot Reloading in Rust? Subsecond and Dioxus to the Rescue

https://codethoughts.io/posts/2026-02-07-rust-hot-reloading/
3•Tehnix•22m ago•1 comments

Skim – vibe review your PRs

https://github.com/Haizzz/skim
2•haizzz•23m ago•1 comments

Show HN: Open-source AI assistant for interview reasoning

https://github.com/evinjohnn/natively-cluely-ai-assistant
4•Nive11•24m ago•6 comments

Tech Edge: A Living Playbook for America's Technology Long Game

https://csis-website-prod.s3.amazonaws.com/s3fs-public/2026-01/260120_EST_Tech_Edge_0.pdf?Version...
2•hunglee2•27m ago•0 comments

Golden Cross vs. Death Cross: Crypto Trading Guide

https://chartscout.io/golden-cross-vs-death-cross-crypto-trading-guide
2•chartscout•30m ago•0 comments

Hoot: Scheme on WebAssembly

https://www.spritely.institute/hoot/
3•AlexeyBrin•33m ago•0 comments

What the longevity experts don't tell you

https://machielreyneke.com/blog/longevity-lessons/
2•machielrey•34m ago•1 comments

Monzo wrongly denied refunds to fraud and scam victims

https://www.theguardian.com/money/2026/feb/07/monzo-natwest-hsbc-refunds-fraud-scam-fos-ombudsman
3•tablets•39m ago•1 comments

They were drawn to Korea with dreams of K-pop stardom – but then let down

https://www.bbc.com/news/articles/cvgnq9rwyqno
2•breve•41m ago•0 comments

Show HN: AI-Powered Merchant Intelligence

https://nodee.co
1•jjkirsch•44m ago•0 comments

Bash parallel tasks and error handling

https://github.com/themattrix/bash-concurrent
2•pastage•44m ago•0 comments

Let's compile Quake like it's 1997

https://fabiensanglard.net/compile_like_1997/index.html
2•billiob•44m ago•0 comments

Reverse Engineering Medium.com's Editor: How Copy, Paste, and Images Work

https://app.writtte.com/read/gP0H6W5
2•birdculture•50m ago•0 comments

Go 1.22, SQLite, and Next.js: The "Boring" Back End

https://mohammedeabdelaziz.github.io/articles/go-next-pt-2
1•mohammede•56m ago•0 comments

Laibach the Whistleblowers [video]

https://www.youtube.com/watch?v=c6Mx2mxpaCY
1•KnuthIsGod•57m ago•1 comments

Slop News - The Front Page right now but it's only Slop

https://slop-news.pages.dev/slop-news
1•keepamovin•1h ago•1 comments
Open in hackernews

'Off switch' discovery could help clear our brains of a common parasite

https://www.sciencealert.com/off-switch-discovery-could-help-clear-our-brains-of-a-common-parasite
49•amichail•1mo ago
https://journals.asm.org/doi/10.1128/msphere.00438-25

Comments

Aurornis•1mo ago
The "off switch" is a protein within the parasite that they turned off with genetic modifications. They didn't actually find a treatment that could be used on wild parasites.

> Gaji and his team might have found a lead, though: in a new study, they have shown that switching off just a single protein inside the microscopic parasite can kill it.

> The protein, TgAP2X-7, appears to be essential to the parasite's ability to invade a host, form plaques, and self-replicate. To prove this, the team genetically modified some parasites so that their TgAP2X-7 proteins function normally unless auxin (a plant hormone that regulates growth) is added, in which case the proteins would quickly degrade.

So it could be helpful research for something, but there are a lot of proteins within parasites that are necessary for growth and survival. Turning any number of proteins off could end the parasite's ability to do something, but that's not helpful unless you also have a mechanism to induce that change without harming the host.

chasil•1mo ago
Toxoplasma Gondii is noted for causing behavioral differences in infected hosts.

https://en.wikipedia.org/wiki/Toxoplasma_gondii#Behavioral_d...

andrekandre•1mo ago
after reading the whole wiki on that thing.... kind of terrifying...

was thinking of getting a cat but maybe not anymore...

adastra22•1mo ago
Just keep your cat indoors.

FWIW the health impacts of a rodent infestation are probably worse than the cat parasite thing. Best defense against mice/rats is a feline friend.

esperent•1mo ago
> Just keep your cat indoors.

Maybe if you have a big house, but I keep seeing people keep cats or dogs in small houses or even apartments and it feels so sad, it's a kind of animal abuse. If you can't give your pet a good life you should not get a pet.

aspect0545•1mo ago
What if it’s a small apartment, but the life is a significant albeit marginal improvement over life in a shelter? Would it make a difference if it were a shelter where animals are killed after a certain period without being adopted?

Please note that I’m on purpose phrasing this to be a bit contrarian. Not trying to rattle any cages (no pun intended), just found myself initially agreeing with you and then not being sure anymore.

adastra22•1mo ago
I grew up with many cats, all outdoor. I have since known many cats that are kept indoor only. The indoor pets lead happier, less stressful lives. We tend to forget that it is a jungle out there, and even domestic animals have territorial fights and pecking orders. Indoor only cats live comparatively peaceful and stress free lives.
Jach•1mo ago
Zoo keepers sometimes experiment with giving their tigers or other big cats larger enclosures, but that can increase their stress because now they have a bigger territory to patrol.
adastra22•1mo ago
Cats love boxes for a reason :)

Growing up my cat would get antsy and stressed if she hadn’t gone outside in a day. I can see how people can mistake this for needing space, but it wasn’t relaxing for her. She had to go out to remark her territory, and seek out any stray cats encroaching on her space. Noticeably very stressful for her! In the end when she couldn’t retainer her territory anymore, she went in fast decline.

DerArzt•1mo ago
If you're in the new world (the Americas) house cats are an invasive species that, when let to roam outside, harm the native small animal population. Cats shouldn't be left outside to roam free in this situation.
adastra22•1mo ago
Small animals that carry lethal diseases.
Wobbles42•1mo ago
Best defense against rats and mice is a ferret friend. Their odor is far more effective at deterring rodents than felines are.
adastra22•1mo ago
Unfortunately illegal to own where I live :(
richardatlarge•1mo ago
And see here :)

https://usop.substack.com/

BobbyTables2•1mo ago
They did tests on human foreskin…

I have some questions about the goals…

pointlessone•1mo ago
Toxoplasma Gondii.

Damn clickbait… it took title, 5 paragraphs, and an ad break before they even mentioned what the parasite is.

pipes•1mo ago
Click bait title.