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A gen AI-discovered TNIK inhibitor for idiopathic pulmonary fibrosis

https://www.nature.com/articles/s41591-025-03743-2
1•frizlab•1h ago

Show HN: TempVault – Share text across devices, no login (built with AI)

https://tempvaultapp.com/en
1•WhiteAndWhite•1m ago•1 comments

What Postgres Taught Me About Building Reliable AI Systems

https://medium.com/@reliable-by-design/from-postgres-migrations-to-ai-pipelines-how-postgresql-sh...
1•iwantchips•1m ago•0 comments

Aethra Programming Language (Music in Codes)

1•CzaxTanmay•4m ago•0 comments

Free ChatGPT 5.2, no account needed on their official /translate page

https://github.com/jonathanyly/freegpt
1•jonathanyly•5m ago•1 comments

NASA Analysis Shows La Niña Limited Sea Level Rise in 2025

https://www.nasa.gov/earth/nasa-analysis-shows-la-nina-limited-sea-level-rise-in-2025/
1•stared•7m ago•0 comments

AI: the US is headed for mass unemployment

https://thehill.com/opinion/finance/5713876-ai-displacement-and-ubi/
4•hackyhacky•8m ago•0 comments

Show HN: Flexboxle – A Daily Puzzle with Flexbox

https://flexboxle.com
1•wluer•8m ago•0 comments

I became a maintainer and all I got was a lousy perspective on librarianship

https://www.hughrundle.net/i-accidentally-became-a-foss-maintainer-and-all-i-got-was-this-lousy-n...
1•yboulkaid•12m ago•0 comments

Are article paywalls dead with LLMs? How has nobody built this

1•amantrying•16m ago•1 comments

Show HN: Open-source is the only way for medicine

https://news.ycombinator.com/
1•pacharanero•16m ago•0 comments

The AI Context Paradox: Engineering Reproducibility and Perpetual Legacy

https://mikelev.in/futureproof/ai-context-paradox-reproducible-legacy/
1•freediver•17m ago•0 comments

CERN supercollider gets sustainable side hustle heating local homes

https://newatlas.com/environment/cern-supercollider-waste-heat-homes/
1•Brajeshwar•17m ago•0 comments

Show HN: How We Run 60 Hugging Face Models on 2 GPUs

1•pveldandi•17m ago•2 comments

Threads' margin is the Eurostack's opportunity

https://pluralistic.net/2026/01/30/zucksauce/
1•lukakopajtic•18m ago•0 comments

Ode to Small Devices

https://spectrum.ieee.org/poetry-for-engineers-ode
1•Brajeshwar•18m ago•0 comments

Another attempt to visualize time and space

https://rtnf.substack.com/p/another-attempt-to-visualize-time
1•altilunium•19m ago•0 comments

Show HN: Nexwork – Multi-repo orchestrator with Git worktrees

https://github.com/Ambot9/Nexwork
1•ambot404•19m ago•0 comments

Researcher reveals evidence of private Instagram profiles leaking photos

https://www.bleepingcomputer.com/news/security/researcher-reveals-evidence-of-private-instagram-p...
2•fleahunter•23m ago•0 comments

How similar AI assisted coding is compared to declarative coding

1•lonelyjohner•24m ago•0 comments

Phenakistoscopes (1833)

https://publicdomainreview.org/collection/phenakistoscopes-1833/
1•tobr•25m ago•0 comments

Men's heart attack risk climbs by mid-30s, years before women

https://news.northwestern.edu/stories/2026/01/mens-heart-attack-risk-climbs-by-mid-30s-years-befo...
2•brandonb•26m ago•0 comments

Proc3D: Procedural 3D Generation and Parametric Editing of 3D Shapes with LLMs

https://arxiv.org/abs/2601.12234
2•PaulHoule•26m ago•0 comments

Resist and Unsubscribe from the tech companies that are enabling this

https://www.resistandunsubscribe.com
9•sbachman•29m ago•3 comments

Show HN: Build reliably with Google GenAI tech thanks to this skills repo

https://github.com/cnemri/google-genai-skills
1•cnemri•30m ago•0 comments

What Is Home-Cooked Software? Touring the Kombucha Programming Language [video]

https://www.youtube.com/watch?v=uxdiKEEfc24
1•surprisetalk•30m ago•0 comments

Rising Temperature

https://arbourtrary.com/sketches/rising-temperature
1•surprisetalk•30m ago•0 comments

Evolution of a Sketch

https://www.davepagurek.com/blog/sketch-evolution/
1•surprisetalk•30m ago•0 comments

Curbing unnecessary Vitamin D testing

https://catalyst.nejm.org/doi/full/10.1056/CAT.25.0237
1•brandonb•30m ago•0 comments

Look for What's True

https://dubroy.com/blog/look-for-whats-true/
1•surprisetalk•30m ago•0 comments

Show HN: AgentOS – A curated list of agentic operating systems

https://github.com/Egv2/awesome-agentOS
1•egemtrak•31m ago•1 comments