I'd never heard of it.
It does seem that it's in a sense pre cancerous although the article seems not to say so outright.
An acquired genetic change, following errors replication and mistakes in cell division that leads to cells having an "advantage". Associated with aging, smoking and increased mortality...
If you didn't know it was about this Y loss, it would seem to be directly referencing a pre cancerous condition.
Human society meanwhile has disrupted a lot of "natural" processes of evolution, so I have no clue how this will play out.
bikenaga•2h ago