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Men lose their Y chromosome as they age – how it may matter

https://theconversation.com/men-lose-their-y-chromosome-as-they-age-scientists-thought-it-didnt-matter-but-now-were-learning-more-275823
12•bikenaga•2h ago

Comments

bikenaga•2h ago
Original title: "Men lose their Y chromosome as they age. Scientists thought it didn’t matter – but now we’re learning more"
rustyhancock•1h ago
Utterly bewildering that this can happen.

I'd never heard of it.

It does seem that it's in a sense pre cancerous although the article seems not to say so outright.

An acquired genetic change, following errors replication and mistakes in cell division that leads to cells having an "advantage". Associated with aging, smoking and increased mortality...

If you didn't know it was about this Y loss, it would seem to be directly referencing a pre cancerous condition.

mrguyorama•1h ago
Human species is "losing", ie evolving away from, the Y chromosome in general. Keeping up an entire Chromosome is expensive and "Inefficient" from evolution's point of view.

Human society meanwhile has disrupted a lot of "natural" processes of evolution, so I have no clue how this will play out.

_aavaa_•3m ago
Nothing’s been “disrupted”. Evolution is occurring the same way it’s always done: through random mutations in response to the environment and sexual selection.
galleywest200•1h ago
Ignorant question: would this mean older fathers are more likely to produce daughters?
yorwba•31m ago
This study says yes, the effect becoming detectable at about 70 years of age: https://jamanetwork.com/journals/jamanetworkopen/fullarticle...

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