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Why optimizing AUC may be insufficient for clinical deterioration systems

1•ameenfayed•2h ago
Medical ML research and competitions often optimize ROC-AUC as the primary performance metric.

However, in real hospital environments, the central question is not classification accuracy — it is escalation timing.

In deterioration detection systems: • A noisy alert creates alarm fatigue. • A late alert costs lives. • A static classifier may fail to reflect dynamic physiology.

I’ve been exploring a framework that introduces: • Dual-threshold activation (high/low) • Temporal stability validation • False-alarm suppression logic • Governed escalation timing

The aim is to shift from probability scoring toward structured decision triggering.

I’m curious how others here would approach modeling escalation timing in a clinically responsible way.

Would love perspectives from ML engineers and clinicians.

David Beazley: An End to Week-Long Immersion Courses

https://buttondown.com/dabeaz/archive/an-end-to-week-long-immersion-courses/
1•kurinikku•3m ago•0 comments

Hemmi/Post 1460 Versalog (Sliderule emulator)

https://thingsabove.github.io/Sliderule-Simulator-with-Solver/react/hemmi_versalog.html
1•todsacerdoti•4m ago•0 comments

Pentagon and Energy Department airlifts nuclear reactor from California to Utah

https://www.pbs.org/newshour/nation/u-s-military-airlifts-small-reactor-for-the-first-time-as-tru...
1•ck2•4m ago•0 comments

NASA astronauts' moon mission delayed due to rocket issue

https://www.bbc.com/news/articles/c626v265zqlo
2•tartoran•6m ago•0 comments

The Problem with AI Agents Isn't Identity, It's Authorization

https://fusionauth.io/blog/ai-authorization
1•mooreds•7m ago•0 comments

Amazon blames human employees for an AI coding agent's mistake

https://www.theverge.com/ai-artificial-intelligence/882005/amazon-blames-human-employees-for-an-a...
3•mooreds•7m ago•1 comments

The 4th Factor

https://lifanzeng.com/the-4th-factor
1•LeafyLi•8m ago•0 comments

Forget Greenland: This Arctic NATO Island Has a Russian Presence

https://www.wsj.com/world/forget-greenland-this-arctic-nato-island-already-has-a-russian-presence...
1•malshe•9m ago•1 comments

OpenAI is Suddenly in Trouble? [video]

https://www.youtube.com/watch?v=-q2n5DkDoMQ
2•CHB0403085482•10m ago•0 comments

Applejak: Interpreter for a subset of K programming language for Super CHIP-8

https://internet-janitor.itch.io/applejak
1•tosh•14m ago•0 comments

Ask HN: What Matters Most in Tech? Awards, Media Praise, or Peer Respect

2•SoundsDebatable•16m ago•3 comments

Show HN: Dq – pipe-based CLI for querying CSV, JSON, Avro, and Parquet files

https://github.com/razeghi71/dq
1•razeghi71•16m ago•0 comments

ChatGPT's hidden bias about your state or city

https://www.washingtonpost.com/technology/interactive/2026/see-chatgpts-hidden-bias-about-your-st...
1•Sherl•16m ago•1 comments

Show HN: GitHub Tray for GNOME gets a big update: notifications, Actions, issues

1•debba•20m ago•0 comments

Metabolism (Architecture)

https://en.wikipedia.org/wiki/Metabolism_(architecture)
1•azhenley•21m ago•0 comments

Ask HN: What's one thing that interested you this week?

1•subdomain•26m ago•0 comments

BreakPoint: Local-first CI gate for LLM output changes (cost, PII, drift)

https://github.com/cholmess/breakpoint-ai
1•cholmess21•29m ago•1 comments

Amazon dethrones Walmart as the world's biggest company by sales

https://www.npr.org/2026/02/19/nx-s1-5719173/amazon-walmart-biggest-company-by-sales
1•geox•30m ago•0 comments

Tube passengers targeted in 'smishing' scam, court told

https://www.bbc.co.uk/news/articles/cg4gkzw971go
1•edward•34m ago•0 comments

Your Android phone has a desktop mode you're probably not using

https://www.makeuseof.com/android-phone-has-desktop-mode-youre-probably-not-using/
3•teleforce•40m ago•0 comments

Democratizing cryptographic silicon verification with Infra-Red imaging (2024)

https://www.bunniestudios.com/blog/2024/iris-infra-red-in-situ-project-updates/
2•transpute•40m ago•0 comments

Symplex Protocol – semantic intent vectors for AI agent communication (Go, v0.1)

https://github.com/olserra/symplex
1•olserra•41m ago•1 comments

The Rise of Invisible Unemployment in Tech: 2026 Will Be the Year It Changes

https://www.saastr.com/the-rise-of-invisible-unemployment-in-tech-2026-will-be-the-year-when-ever...
1•bentobean•43m ago•0 comments

Ask HN: How do you monitor and retry failed webhooks in production?

2•GoatPerfect•43m ago•2 comments

Write Perfect Emails in Seconds

4•vinayofc•43m ago•0 comments

The New Mexico cave expanding our search for alien life

https://www.bbc.com/future/article/20260130-how-deep-caves-are-transforming-our-search-for-extrat...
2•marc__1•43m ago•0 comments

Functionalized Coatings as Biohybrid UV-Sensors

https://advanced.onlinelibrary.wiley.com/doi/10.1002/admi.202500125
1•PaulHoule•43m ago•0 comments

Show HN: PrivateOS: An AI agent that runs on your phone

https://private-os.vercel.app
3•pruthvi77•45m ago•1 comments

CipherDrop

https://www.cipherdrop.app/
1•shablulman•46m ago•0 comments

Announcing Oracle Solaris 11.4 SRU90

https://blogs.oracle.com/solaris/announcing-oracle-solaris-11-4-sru90
3•pjmlp•47m ago•0 comments