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Small-molecule inverse agonist of PPARγ for advanced solid tumors

https://www.nature.com/articles/s41591-026-04263-3
1•bookofjoe•1h ago

The Summer Slide, part 3: The tax code we had

https://substack.com/@michaelwgreen/p-189483869
1•jez•43s ago•0 comments

NoEyes – Terminal-based, self-hosted end-to-end encrypted chat in Python

https://github.com/Ymsniper/NoEyes
1•Ymsniper•1m ago•1 comments

Show HN: Agent-Audit – Lint and cost-estimate your AI agent

https://github.com/AreteDriver/agent-audit
1•aretedriver•3m ago•0 comments

The growing corpus of problems that are 'easy' for entities which may not think

https://zjpea.substack.com/p/embarrassingly-solved-problems
1•zjp•5m ago•0 comments

Show HN: I built a fast mood, energy, and activity tracker (trilog.app)

https://trilog.app
1•saltroad•7m ago•0 comments

Claude hits #1 on the App Store as users rally behind Anthropic

https://9to5mac.com/2026/03/01/claude-hits-1-on-the-app-store-as-users-rally-behind-anthropics-go...
3•doctoboggan•9m ago•0 comments

Earn Compute Credits

https://www.hpc-ai.com/blog/Share-And-Earn-Social-Media-Campaign
1•hpcaitech•10m ago•0 comments

Secure LLM Scripting. Finally

https://mlld.ai/
1•dahjelle•14m ago•0 comments

RunWatch – CI/CD Observability for GitHub and GitLab

https://runwatch.io
1•toconnor•14m ago•1 comments

We will sacrifice quality for convenience

https://twitter.com/backnotprop/status/2028293637373841759
4•ramoz•14m ago•0 comments

Readout

https://www.readout.org/
1•handfuloflight•15m ago•0 comments

Dual chamber microbial fuel cells using human urine

https://www.sciencedirect.com/science/article/pii/S2211715625008719
1•PaulHoule•17m ago•0 comments

The Metamorphosis of Prime Intellect (1994)

https://localroger.com/prime-intellect/mopiidx.html
1•nz•19m ago•0 comments

There Are Many Ways to Read Hacker News

https://readhacker.news/
1•TigerUniversity•20m ago•0 comments

Show HN: Anime AI Agent for end-to-end anime short creation

https://www.animeaistudio.com/anime-ai-agent
1•deepseekai•21m ago•2 comments

The Crossing Guard Making $14,000 a Month Mailing Out Her Musings from the Job

https://www.wsj.com/lifestyle/careers/crossing-guard-mail-club-14-000-a-month-42afb85d
1•impish9208•22m ago•1 comments

Read Michel de Montaigne's Essays in Modern English

https://magicreader.com/montaigne
1•mzelling•32m ago•0 comments

Block and Tackle: Job Cuts and the AI Narrative

https://om.co/2026/02/28/block-tackle-job-cuts-the-ai-narrative/
1•qwikhost•33m ago•1 comments

Smallest QR Code Is So Tiny It's Invisible to the Human Eye

https://www.sciencealert.com/worlds-smallest-qr-code-is-so-tiny-its-invisible-to-the-human-eye
1•rendx•35m ago•0 comments

Show HN: Foundations Chat, macOS AI chat built on Apple's local models

https://codeeverywhereca.github.io/foundations-chat/
1•coevcan•37m ago•0 comments

A curious phenomenon called 'Etak' (2024)

https://maphappenings.com/2024/04/11/story-of-etak/
1•giancarlostoro•38m ago•0 comments

The limited utility of the phrase "GNU/Linux" (2022)

https://seirdy.one/posts/2022/12/09/limited-utility-gnu-linux/
1•LorenDB•39m ago•0 comments

Show HN: Sun – Realtime voice agent for group conservation not just turn taking

https://www.getsun.io/
3•anand_pattern•40m ago•2 comments

A semantic Code Search CLI but with grep filters

https://github.com/lightonai/next-plaid
1•raphaelty•45m ago•1 comments

Swarming, spinning microrobots can manipulate their surroundings

https://news.cornell.edu/stories/2026/02/swarming-spinning-microrobots-can-manipulate-their-surro...
1•geox•53m ago•0 comments

I'm Sorry This New Artist Sucks [video]

https://www.youtube.com/watch?v=eKxNGFjyRv0
1•thunderbong•56m ago•0 comments

Opponent Modeling Wins 2× Faster Than Stockfish

https://blog.lukesalamone.com/posts/winning-faster-than-stockfish/
1•salamo•57m ago•0 comments

Personal token: share equity in your lifetime upside

https://github.com/homan9/personal-token/blob/main/whitepaper.md
1•koopuluri•1h ago•0 comments

Future of Devtools and Moats

https://ravivyas.com/2026/03/01/dev-tools-and-moats
2•ravivyas•1h ago•1 comments

Piezoelectric gel to regenerate lost bone (e.g. periodontitis)

https://oralbiolife.com/
2•camebeforeagain•1h ago•1 comments