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Biohacker claims to have sequenced their own genome with M3 Ultra Mac Studio

https://www.tomshardware.com/tech-industry/artificial-intelligence/biohacker-claims-to-have-sequenced-their-own-genome-at-the-kitchen-table-with-m3-ultra-mac-studio-claude-and-a-usd3-200-sequencer-diy-project-requires-100gb-of-data-storage-per-run-oodles-of-ram
2•rmason•1h ago

Comments

rmason•1h ago
It's rather cool that this guy was able to do it himself. But it cost him more than if he got an outside lab to do it for him. Maybe it's worth the premium not to have his DNA in a federal law enforcement database. Pretty soon I'd be willing to bet you'd need to run your llm locally if that was your primary concern.
dekhn•1h ago
The main issue is there really no good way to take an action based on a manually sequenced genome like this right now, with a few exceptions.

It's good to know what can be done at home with reasonable costs for the hardware and software, but one should not expect this to produce somethign that will change your life for the better.

ICE detains wife of US Army soldier at immigration appointment

https://www.bbc.com/news/articles/c8r460gj7eko
3•tartoran•2m ago•0 comments

F-35s Quarterbacking Drones Seen as Gateway to USMC's 6th Gen Fighter

https://www.twz.com/air/f-35s-quarterbacking-drones-seen-as-gateway-to-usmcs-6th-gen-fighter
3•breve•3m ago•0 comments

Grasshopper: Advanced Tab Manager

https://addons.mozilla.org/en-US/firefox/addon/grasshopper-urls/
1•madprops•8m ago•0 comments

Qualtrics Survey Licensing Cost

1•rajivijay•9m ago•1 comments

Kahtooee.com

https://kahtooee.com
1•canihelpai•12m ago•0 comments

GCC 16 Compiler Nearly Ready for Release with Zen 6, AVX10.2, APX and Algol 68

https://www.phoronix.com/news/GCC-16.1-Coming-Soon
1•rbanffy•13m ago•0 comments

The Neon King of New Orleans

https://gardenandgun.com/new-orleans-neon-king
4•renameme•13m ago•0 comments

The Second Time Will Be the IPO Charm for Cerebras

https://www.nextplatform.com/compute/2026/04/22/the-second-time-will-be-the-ipo-charm-for-cerebra...
1•rbanffy•14m ago•0 comments

Chaotic fluctuations mark mental activity in task-based heart rate variability

https://www.nature.com/articles/s41598-026-43385-z
2•bookofjoe•14m ago•0 comments

How are we supposed to use AI?

https://petersmj.com/blog/technology-in-research/
1•petersmj•18m ago•1 comments

CATL to launch sodium-ion batteries in EVs in 2026, aiming for 370 miles range

https://electrek.co/2026/04/22/catl-launching-sodium-ion-batteries-evs-2026/
3•breve•20m ago•0 comments

Women in Gaza Sexually Abused by Hamas Fighters

https://www.dailymail.com/news/article-15732903/Women-living-Hamas-rule-Gaza-Mail-sexually-abused...
4•transfer92•20m ago•0 comments

Browser for Agents in a form of CLI, API or library

https://github.com/zarkones/Moroi-Browser
1•ZARKONES•23m ago•0 comments

Kalshi suspends 3 congressional candidates in 'insider trading' enforcement

https://www.cnbc.com/2026/04/22/kalshi-insider-trading-congress.html
1•shinryudbz•26m ago•0 comments

Investors lost billions on Trump's memecoin. Another gala won't fix that

https://arstechnica.com/tech-policy/2026/04/investors-lost-billions-on-trumps-memecoin-another-ga...
4•rbanffy•26m ago•0 comments

X is going to let Grok curate your timeline

https://www.theverge.com/tech/917113/x-ai-grok-timeline-curation
1•omer_k•27m ago•0 comments

The opportunity is in building ethical software that respects users needs

https://bhurghundii.substack.com/p/the-opportunity-is-in-building-ethical
1•sailorganymede•28m ago•0 comments

Bolt AI builder: Create apps and websites by chatting with AI

https://bolt.new
1•doener•28m ago•0 comments

My GLM-5.1 coding agent scored 94.3% on LiveCodeBench Lite (348/369)

3•univence•29m ago•0 comments

Failed Companies Are Selling Old Slack Chats and Email Archives to Train AI

https://gizmodo.com/failed-companies-are-selling-old-slack-chats-and-email-archives-to-train-ai-2...
4•CGMthrowaway•36m ago•1 comments

A Sony Walkman for the Spotify Era

https://nymag.com/strategist/article/sony-walkman-nwa306-review-2026.html
3•HardwareLust•39m ago•0 comments

Personal computing in the Anthropocene with eyes, minds and hearts wide open

https://smol.earth/manifesto.html
2•NoGravitas•44m ago•0 comments

Jeff Bezos Nears $10B Funding Round for Project Prometheus

https://www.bloomberg.com/news/articles/2026-04-21/jeff-bezos-nears-10-billion-funding-round-for-...
4•gmays•45m ago•2 comments

Sintopia

https://store.steampowered.com/app/2213700/Sintopia/
2•doener•46m ago•0 comments

Ars Technica newsroom AI policy

https://arstechnica.com/staff/2026/04/our-newsroom-ai-policy/
7•LorenDB•47m ago•1 comments

Hofmann Typeface (2023)

https://www.itsnicethat.com/articles/nguyen-gobber-hofmann-graphic-design-project-111223
1•NKosmatos•47m ago•0 comments

Olive CSS: Lisp powered vanilla CSS utility-Class A la Tailwind

https://codeberg.org/jjba23/olive-css
5•jjba23•49m ago•1 comments

Sacrifice your job for the glorious AI future

https://disconnect.blog/sacrifice-your-job-for-the-glorious-ai-future/
2•cdrnsf•49m ago•0 comments

Creativity Harness: Adobe will be fine

https://avkcode.github.io/blog/creative-widgets-should-produce-files.html
1•KyleVlaros•54m ago•0 comments

Microplastics in testicles may play a role in male infertility, study suggests

https://weillcornell.org/news/microplastics-in-testicles-may-play-a-role-in-male-infertility-stud...
1•vinni2•54m ago•0 comments