frontpage.
newsnewestaskshowjobs

Made with ♥ by @iamnishanth

Open Source @Github

fp.

Open in hackernews

A DNA-Based Archival Storage System [pdf]

https://homes.cs.washington.edu/~luisceze/publications/dnastorage-asplos16.pdf
2•cats_and_dogs•1h ago

Comments

cats_and_dogs•1h ago
Found this interesting paper about using DNA for archival storage.

Abstract: Demand for data storage is growing exponentially, but the capacity of existing storage media is not keeping up. Using DNA to archive data is an attractive possibility because it is extremely dense, with a raw limit of 1 exabyte/mm3 (109 GB/mm3 ), and long-lasting, with observed half-life of over 500 years. This paper presents an architecture for a DNA-based archival storage system. It is structured as a key-value store, and leverages common biochemical techniques to provide random access. We also propose a new encoding scheme that offers controllable redundancy, trading off reliability for density. We demonstrate feasibility, random access, and robustness of the proposed encoding with wet lab experiments involving 151 kB of synthesized DNA and a 42 kB randomaccess subset, and simulation experiments of larger sets calibrated to the wet lab experiments. Finally, we highlight trends in biotechnology that indicate the impending practicality of DNA storage for much larger datasets.

Gracchi Brothers

https://en.wikipedia.org/wiki/Gracchi_brothers
1•mooreds•1m ago•0 comments

CLI loop: A panel of AI agents that peer-reviews anything

https://github.com/zulman/peer-review
1•gamescodedogs•2m ago•0 comments

The blood cancer that became solvable

https://worksinprogress.co/issue/the-blood-cancer-that-became-solvable/
1•speckx•2m ago•0 comments

Do the Hardest Thing

https://justinjackson.ca/hard-thing
1•levhawk•3m ago•0 comments

Dreaming: Better memory for a more helpful ChatGPT

https://openai.com/index/chatgpt-memory-dreaming/
1•meetpateltech•6m ago•0 comments

Phoenix Is a Data-Center Mecca–and Test Case for How to Pay for AI's Power Needs

https://www.wsj.com/business/energy-oil/phoenix-is-a-data-center-meccaand-test-case-for-how-to-pa...
1•JumpCrisscross•6m ago•0 comments

Thou shalt not make a machine in the likeness of a human mind

https://github.com/RsyncProject/rsync/issues/950
2•tosti•8m ago•0 comments

Retro-Tech Parenting

https://havenweb.org/2026/05/28/retro-tech.html
1•mawise•8m ago•0 comments

Why Are My Emails Going to Spam? An Authentication-First Fix

https://dmarcguard.io/blog/emails-going-to-spam/
1•meysamazad•10m ago•0 comments

They're Made Out of Makes

https://gist.github.com/alganet/d70eb7f48e64818cae9efbc599449ada
1•gaigalas•10m ago•0 comments

Set Up Your Own DoH Service

https://blawg.nochan.net/b/Internet-Crap/20260602-Set-Up-Your-Own-DoH-Service/
1•Bender•11m ago•0 comments

$560 AWS m6i.4xlarge VM refused to read the room

https://webbynode.com/articles/aws-m6i-4xlarge-refused-to-read-the-room
2•gsgreen•11m ago•1 comments

Slop Forks

https://karldaniel.co.uk/slop-forks/
1•speckx•11m ago•0 comments

Show HN: Open Terminal – A Bloomberg Style App for Research

https://tesseractanalytics.ai/
2•tessbi•11m ago•0 comments

AI top-down, Evolution bottom-up

https://chaseadam.com/ai-and-evolution
1•chaseadam17•12m ago•0 comments

Congress set to unveil AI draft that would preempt state laws

https://www.politico.com/news/2026/06/04/obernolte-trahan-ai-bill-lands-on-the-hill-00949920
3•artninja1988•16m ago•0 comments

Fast and Efficient LLM Inference with vLLM: A New Course with Deeplearning.ai

https://vllm.ai/blog/2026-06-03-deeplearning-ai-vllm-course
2•sonabinu•17m ago•0 comments

El Poblador – Settlers of Catan TUI

https://sr.ht/~vicho/el_poblador/
1•gslin•18m ago•0 comments

Road to WWDC 2026: What's a developer?

https://sixcolors.com/post/2026/06/road-to-wwdc-2026-whats-a-developer/
1•mistersquid•20m ago•0 comments

Nvidia released Nemotron 3 Ultra, a new open model

https://developer.nvidia.com/blog/nvidia-nemotron-3-ultra-powers-faster-more-efficient-reasoning-...
3•acoye•22m ago•0 comments

Common Lisp bindings for brotli compression

https://codeberg.org/fsm/cl-brotli
1•fsmunoz•22m ago•1 comments

Unix, Everything Is a File

https://vivianvoss.net/blog/unix-everything-is-a-file
3•speckx•22m ago•1 comments

Map Age Guide

https://xkcd.com/1688/
1•taubek•23m ago•0 comments

How Long Does It Take to Plan a Bridge?

https://www.construction-physics.com/p/how-long-does-it-take-to-plan-a-bridge
1•crescit_eundo•23m ago•0 comments

Not the Same Kid

https://www.quarter--mile.com/Not-The-Same-Kid
2•surprisetalk•25m ago•0 comments

This Month in Agentic Coding: May 2026

https://www.agenticcodingweekly.com/p/acw-monthly-brief-may-2026
4•primaprashant•27m ago•0 comments

Google Employees Internally Share Memes About How Its AI Sucks

https://www.404media.co/google-employees-internally-share-memes-about-how-its-ai-sucks/
21•elorant•28m ago•2 comments

Show HN: Kyu Launcher – Roku Interface on Your Android and Google TV

https://kyulauncher.com/
2•avadhesh18•28m ago•0 comments

US tech sector cut 38,242 jobs in May, AI the most cited reason for layoffs

https://www.tomshardware.com/tech-industry/artificial-intelligence/tech-sector-cut-us-jobs-by-382...
9•heresie-dabord•28m ago•0 comments

SpaceX CFO presents business drivers

https://twitter.com/elonmusk/status/2062548455570985377
2•__patchbit__•29m ago•0 comments