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You may be taking the wrong painkiller

https://dynomight.net/painkillers/
4•colinprince•2h ago

Comments

ggm•1h ago
Voltarin is another NSAID. It's heinous on the gut so I avoid it. But, it's available as a topical gel/cream. If this can have any specificity to site and differential blood levels are a thing, it's possible using voltarin topically for skeleto-muscular pain is different to swallowed.

There's also Naproxen. It's another NSAID. It's super effective for brief periods. I am massively autosuggestive and continue to believe high dose naproxen makes me high but that's me. Maybe I'm happy because the pain went away. I never take for more than 2-3 days.

My point is that certainly for routine pain management the big two are right there, paracetamol and ibuprofen. But there are other tools in the armoury, before we get to the opioids.

Premptive use of ibuprofen to reduce swelling before sport? Yay or nay? Risks of over extension and more damage because defensive/signalling pain and swelling is maybe a thing ?

apothegm•1h ago
Fwiw, my understanding is that naproxen works very similarly to ibuprofen and is simply stronger (and possibly longer-acting), with similar but proportionally greater side effects. I take it rarely for that reason, but it feels an order of magnitude more effective.

Ask HN: How do you test AI-generated code?

1•df003•15s ago•0 comments

The Untold Story of an Acid Medium

https://mitpress.mit.edu/9780262048507/blotter/
1•tzury•4m ago•0 comments

Deltatensors – store model fine-tunes as compressed weight deltas

https://github.com/AaravGaurdev/deltatensors
2•AaravGaur•7m ago•1 comments

Anthropic-Cybersecurity-Skills:817 structured cybersecurity skills for AI agents

https://github.com/mukul975/Anthropic-Cybersecurity-Skills
3•aurenvale•7m ago•0 comments

Moody Mush: An Interactive Mushroom Robot

https://www.instructables.com/Moody-Mush/
1•RRWagner•11m ago•1 comments

Dkamd

https://news.ycombinator.com/submit
1•Solmyst•12m ago•0 comments

Stop coding agents from writing prolix comments

https://github.com/DanverImbue/crispy-comments
1•nvader•15m ago•0 comments

Is working in AI training data a waste of time?

https://joinhandshake.com/ai/opportunities/generalist-bachelor-s2/
1•mazaltime•17m ago•1 comments

Where U.S. Salary Ranges Help Job Seekers

https://corvi.careers/blog/salary-range-clarity-role-state-metro-rankings/
1•sp1982•18m ago•0 comments

Show HN: A leaderboard of most popular open-weight LLMs

https://osolmaz-leaderboard.hf.space/
1•hosolmaz•21m ago•0 comments

Catbath – a tiny text editor in Rust with edit over SSH and web editor in 456KB

https://github.com/skorotkiewicz/catbath
2•modinfo•24m ago•0 comments

AI was supposed to make smarter decisions. Iit may be making leaders dangerous

https://www.youtube.com/watch?v=NTeF1NmmZWA
4•orionblastar•26m ago•2 comments

Lianda and the Long March

https://blog.georeactor.com/books-06-26b
2•mapmeld•28m ago•0 comments

LineShine Debuts at No. 1 as the TOP500 Enters a New Global Exascale Era

https://top500.org/news/lineshine-debuts-no-1-top500-enters-new-global-exascale-era/
4•jonbaer•33m ago•0 comments

US AI stock sell-off shakes markets from Wall Street to Asia

https://www.theguardian.com/business/2026/jun/23/ai-stocks-sell-off-us-markets
8•colinprince•38m ago•0 comments

Want to feel happier at work? Take a five-minute walk

https://www.bbc.com/news/articles/c78yzz936evo
4•tagawa•42m ago•2 comments

Sakana Fugu: a multi-agent system delivered as one model

https://github.com/SakanaAI/fugu
6•aurenvale•43m ago•1 comments

US presses Meta to agree to AI reviews as security fears rise

https://www.nytimes.com/2026/06/23/business/meta-ai-government-reviews-security.html
2•anigbrowl•43m ago•0 comments

Can a $1,500 Battery Replace a Powerwall? [video]

https://www.youtube.com/watch?v=jl-rwZjdD3Y
3•nikodunk•47m ago•1 comments

BenchPress: Predict any LLM's score on any benchmark

https://microsoft.github.io/benchpress/
3•berlianta•52m ago•0 comments

Legibility of Effort

https://eieio.games/blog/legibility-of-effort/
2•bobbiechen•55m ago•0 comments

Raspberry Pi Pico W as USB Wi-Fi Adapter

https://gitlab.com/baiyibai/pico-usb-wifi
5•byb•57m ago•2 comments

Ions, a distributed reasoning graph built from evidence backed claims

https://github.com/nomad505050/ions-genesis
5•nomad55•1h ago•0 comments

I built an open source VAD that beats Silero, Pyannote, and WebRTC

https://github.com/monishmal3375/nova-vad
4•hellothisismm•1h ago•0 comments

Technology-Driven Moral Panics

https://techlashed.org/
4•gjvc•1h ago•0 comments

Mythos model found vulnerabilities in classified US Government systems

https://apnews.com/article/anthropic-mythos-ai-classified-systems-vulnerabilities-testing-3e8762c...
4•josephwegner•1h ago•0 comments

Ten years on, Brexit's economic impact is becoming clearer

https://www.bbc.co.uk/news/articles/cyv0m164m84o
11•mellosouls•1h ago•2 comments

RRB-Trees: Efficient Immutable Vectors

https://infoscience.epfl.ch/server/api/core/bitstreams/e5d662ea-1e8d-4dda-b917-8cbb8bb40bf9/content
3•azhenley•1h ago•0 comments

2026: The year of the node based editor

https://medium.com/@fadimantium/2026-the-year-of-the-node-based-editor-941f0f15d467
4•soupspaces•1h ago•3 comments

Congress Clears Housing Bill, Cementing a Rare Bipartisan Feat

https://www.nytimes.com/2026/06/23/us/politics/congress-housing-bill.html
11•mikhael•1h ago•7 comments