Ending All Respiratory Infections

https://blog.interceptfund.com/p/ending-respiratory-infections

35•EthanFantl•1h ago

Comments

NDlurker•1h ago

My girlfriend died from human metapneumovirus at 30 years young. She had a weakened immune system from lymphangiomatosis, so something like metapneumovirus, which is a mild illness for most people, was a death sentence for her. I hope this fund is successful so nobody else ever has to go through what she did.

oscarmcdougall•1h ago

Sorry for your loss.

amatecha•46m ago

As someone who still masks (KN95) in all indoor settings where unmasked people are present, I am all for this. Very much looking forward to seeing where it leads.

happyopossum•33m ago

> Healthy people spend roughly 15-25 days each year—about 5% of their lives—sick with respiratory infections like the common cold and influenza

This seems completely unbelievable to me. Totally outside of my personal, professional, and family experience.

j4k0bfr•24m ago

This feels about right to me. Living with kids and commuting via public transport (in a country where face masks are not common) might break 5%.

mberning•24m ago

For my family of 5 w/ school age children I would say that is a pretty reasonable estimate, maybe even a bit low for us. There are levels of “sick” though and I would say for us most respiratory illnesses are very mild and are a minor annoyance. Where it becomes more menacing is when we have sick kids and sick parents at the same time.

tibbar•7m ago

Unbelievable in which direction?

I've had years in which most people in my immediate surroundings were sick for weeks or months (likely exacerbated by mold, school, and travel). Also years in which I never really got sick at all.

Getting sick that often is pretty debilitating.

fred_is_fred•30m ago

My son is susceptible to these type of infections and has asthma. He missed 17 days of school last year. Even if not fatal these types of infections are miserable and have an impact on those who get them and their caretakers.

nxc18•28m ago

I was really disappointed that air cleaning didn’t take off after Covid. Super disappointing to see society just collectively decide to not learn any lessons.

Even if there were no mortality or productivity benefits, you’d think cutting down on cold and flu would be sufficient motivation on its own. Especially in schools and other high risk places.

Kudos to these people.

mberning•22m ago

We had twins after having a singleton during covid. We invested in 4 big hepa air filters and placed one in each bedroom. I think it significantly reduced the amount of illnesses we faced in the first year if the twins life. Lesson learned for us.

Spartan-S63•24m ago

I'd be interested to see more concerted research into contagious/self-replicable vaccines that are self-replicating and spreadable to a wider swath of people. That seems like a step forward in public health prevention for seasonal illnesses that we have well-engineered and safe vaccines for.

I understand the bar for deployment would need to be high to ensure that side effects are even rare compared to typical voluntary vaccinations.

alex43578•15m ago

1) There’s no way the public would buy in to this idea. 2) This seems like a serious violation of medical ethics. 3) If we already gave a well-engineered and safe vaccine, why not take that? Supply chain and immunization itself isn’t a practical choke point: it’s vaccine accuracy for things like flu, and vaccine misinformation for something like measles. But again, take the vaccine or don’t: for most illnesses and most scenarios, you’re only hurting yourself.

Null-Set•10m ago

> We surveyed attendees ahead of the symposium. One of our questions was: if this doesn’t happen in the next ~10 years, what will the primary reason be? The number one reason cited was lack of funding, followed by technical feasibility. Why hasn’t this field attracted sufficient funding, especially given the enormous societal burden?

Isn't a projected problem with technical feasibility an explanation for lack of funding?

a_t48•7m ago

As someone currently with a nasty cold, having to work through it anyhow - please.

EthanFantl•5m ago

I am so tremendously excited to see this, I've had quite a few friends become permanently disabled from long covid and even have some lingering symptoms myself from my last infection and so anything to improve access and uptake of air cleaning technologies and new preventatives is amazing.

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