Scientists reverse brain aging, with a nasal spray

https://stories.tamu.edu/news/2026/04/14/scientists-reverse-brain-aging-with-a-nasal-spray/

93•cybermango•1h ago

Comments

amingilani•1h ago

...in mice.

> Therefore, this study examined the effects of late middle-aged (18-month-old) male and female C57BL6/J mice receiving two intranasal doses of hiPSC-NSC-EVs on neuroinflammaging in the hippocampus at 20.5 months of age.

— https://isevjournals.onlinelibrary.wiley.com/doi/10.1002/jev...

doginasuit•59m ago

To be fair though, I think we owe the mice a positive research outcome.

antonvs•45m ago

“Congratulations, you get improved brain function while we continue to run other experiments on you!”

earthnail•36m ago

“There will be cake!”

ghurtado•16m ago

You can now experience both physical pain and existential dread!

tryagainian•2m ago

On the plus side, expect to see great works of literature authored by rodents.

switchbak•58m ago

That PR piece was brutal to navigate. Undoubtedly punched up by AI, it took far too long to even understand what the treatment entailed.

SubiculumCode•27m ago

The link to the actual paper was appreciated. The context of whether findings will generalize outside of mouse models can depend a lot on specifics of the problem.

fuckinpuppers•55m ago

Mice get all the cool shit first

jjtheblunt•49m ago

they get all the worst and most inane tortures too

secretslol•45m ago

I even seen a mouse on youtube with it's own tiny EV sports car driving about!

dlcarrier•11m ago

I read a book about a mouse with a motorcycle (https://www.goodreads.com/en/book/show/232109.The_Mouse_and_...) and a different book about a mouse-like child with sailboat. (https://www.goodreads.com/en/book/show/138959.Stuart_Little).

M. Night Shyamalan wrote a screenplay about the latter book, and it was made into a popular movie.

hoppp•14m ago

Then they get murdered...

earth-tattoo•43m ago

That's exactly what I want: immortal mice!

ghurtado•18m ago

That's a surprisingly underused plot for a sci Fi horror film.

Considering the grand total of experiments we've ran on the little guys, I'm kinda surprised we haven't bred Mousezilla yet

dlcarrier•14m ago

You joke, but rodents make great pets, because they are very social and have a range of personalities, but most only live a few years. I knew someone with a pet retired lab rat, and it lived much longer than the average fancy rat, but even then, it didn't even live half as long as the average cat or dog.

If we could breed or treat rodents to live longer, we could keep low-resource pets without as much loss.

SubiculumCode•31m ago

High impact journal for an interesting study that is admittedly largely out of my area of expertise. The limitation of it being done in animal models, is of course, noted, but also expected. The question I would ask is how well the underlying background research makes this outcome expected.

block_dagger•31m ago

Flowers for Algernon’s Brain

gavinray•19m ago

"Reverse brain aging", sure, in the same sense that taking Vitamin C reverses aging.

The nasal spray reduced markers of inflammation in hippocampal microglial cells.

A lot of things reduce inflammation. That is not "reversing ageing".

Of course, "reduces inflammation" doesn't headline very well...

mawadev•13m ago

The article is also heavily ai generated, I call bs on every single bit

dwa3592•12m ago

c'mon you guys, chill. this is not a vaccine.

bigmattystyles•11m ago

I thought the url said temu at first.

rylando•10m ago

Kinda surprised A&M’s letting them use AI to write these things

dwa3592•7m ago

>>The article is also heavily ai generated

can you please share your methodology for detecting ai please?

asdf88990•

general_reveal•18m ago

When can I snort this?

hoppp•15m ago

Prepare a line for me also please

tryagainian•5m ago

Grab me a bag while your there.

hoppp•16m ago

I take N-acetylcysteine and it helps with brain fog also! Plus it reduces stress and irritability.

keepamovin•12m ago

Ugh, I thought we were done with the Boomers....looks like they're gonna hang on.

timmg•10m ago

How soon until biohackers try this on themselves?

catlifeonmars•8m ago

[delayed]

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Scientists reverse brain aging, with a nasal spray

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