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AMD EPYC 9006 Venice Announced and Looks Poised to Be a Grand Slam

https://www.phoronix.com/review/amd-epyc-9006-venice
2•rbanffy•2m ago•0 comments

Looking for Feedback on Website

https://www.what2do.me/
1•gnrlnoob•3m ago•0 comments

How Tether Benefited as Trump Insiders Shaped First Crypto Law

https://www.bloomberg.com/features/2026-howard-lutnick-bo-hines-trump-tether-crypto-law/
1•petethomas•3m ago•0 comments

The Gospel of Gains: How Fitness Culture Went Mainstream

https://greyenlightenment.com/2026/06/30/the-all-the-gospel-of-gains-how-fitness-culture-went-mai...
1•paulpauper•5m ago•0 comments

Microsoft deleted Nokia's archive of unreleased ringtones in 2016 HMD sale

https://bsky.app/profile/techprodbangers.bsky.social/post/3mr4askb6tk2i
1•scblzn•5m ago•0 comments

Kalytera – tells you why your AI agent failed, not just that it did

https://kalytera.dev/
1•mathurpriya19•7m ago•0 comments

Locked in An Escape Room with Jacob Tsimerman

https://www.begiant.ca/stories/people/jacob-tsimerman-math
1•tibbar•7m ago•0 comments

DOE Fires the $5B Starter Gun for Its AI-Targeted Genesis Mission

https://www.nextplatform.com/hpc/2026/07/23/doe-fires-the-5-billion-starter-gun-for-its-ai-target...
1•rbanffy•8m ago•0 comments

The AI Productivity Paradox

https://www.svpg.com/the-ai-productivity-paradox/
1•andrii•10m ago•0 comments

Show HN: How far do I have to go to run into 100k people?

https://imjasonh.github.io/playground/population-rays/
1•ImJasonH•11m ago•0 comments

Sometimes Being First Means Seeing the End Before Anyone Else

https://www.quantamagazine.org/jacob-tsimerman-wins-2026-fields-medal-for-andre-oort-conjecture-p...
3•energy123•12m ago•0 comments

AI Agents Don't Respect Font Licenses

https://www.mixfont.com/blog/ai-agents-dont-respect-font-licenses
2•jenthoven•14m ago•0 comments

Show HN: Advanced Coffee Search Covering Over 17,000 coffees

https://beangenie.coffee/coffee
2•epicwynn•14m ago•0 comments

Show HN: Connecting my dumb garage and car's homelink button to Home Assistant

https://dsauerbrun.com/writing/dumb-garage
1•dsauerbrun•15m ago•0 comments

US announces double-digit tariffs on most of globe to replace expiring duties

https://finance.yahoo.com/economy/policy/article/trump-administration-announces-the-next-phase-of...
4•ck2•15m ago•2 comments

Tesla shares tumble 11% after discounts hit profits

https://www.ft.com/content/dc5e629b-562c-41e3-8b89-350af6960adc
2•doener•17m ago•0 comments

What Happened When Flock Came to My Town

https://www.404media.co/what-happened-when-flock-came-to-my-town/
1•Jimmc414•18m ago•0 comments

Lazarus Group Using Git Hooks to Hide Malware – Open-Source Malware Blog

https://opensourcemalware.com/blog/lazarus-group-uses-git-hooks-to-hide-malware
3•vinnyglennon•18m ago•0 comments

California legislature removes REAL-ID compliance from Governor's budget

https://papersplease.org/wp/2026/06/15/california-legislature-removes-real-id-compliance-from-gov...
2•Jimmc414•19m ago•0 comments

Blacklight, our privacy inspector tool, now tracks X and TikTok pixels

https://themarkup.org/blacklight/2026/02/09/blacklight-update-tiktok-x-twitter
1•Jimmc414•19m ago•0 comments

FDA reports new outbreak of explosive diarrhea with 72 cases identified

https://arstechnica.com/health/2026/07/fda-reports-new-outbreak-of-explosive-diarrhea-with-72-cas...
4•nianderwallace•20m ago•0 comments

Oracle signs 10-year software contract with Pentagon worth up to $7B

https://www.cnbc.com/2026/07/23/oracle-wins-10-year-pentagon-software-contract-worth-up-to-7-bill...
3•srameshc•21m ago•0 comments

Pinjour – An App for the Outdoors

https://jfornear.com/2026/07/24/pinjour-photo-maps/
2•flowmerchant•25m ago•0 comments

Ask HN: What's a great opening line you know?

2•chistev•26m ago•3 comments

Mark Zuckerberg launches AI optimism campaign

https://www.axios.com/2026/07/23/mark-zuckerberg-ai-optimism
4•andsoitis•26m ago•1 comments

Pip install Postgres – no Docker/Brew/apt

https://github.com/leontrolski/postgresql-testing
1•leontrolski•26m ago•1 comments

The first racket sport smart wearable

https://aurevo-rose.vercel.app/
1•elilourens•28m ago•1 comments

Dog Photographer Loses Copyright Case over AI-Generated Version of Her Image

https://petapixel.com/2026/07/22/dog-photographer-loses-copyright-case-over-ai-generated-comic-ve...
3•ColinEberhardt•28m ago•1 comments

Why Trump's Neglect of Working Families Is a Wake-Up Call for Voters

https://bluepressjournal.substack.com/p/the-housing-bill-snub-why-trumps
2•WinstonWendell•29m ago•0 comments

Google reportedly working on ultra-efficient AI chip for Gemini

https://thedailycompute.beehiiv.com/p/google-reportedly-working-on-ultra-efficient-ai-chip-for-ge...
2•theanonymousone•30m ago•0 comments
Open in hackernews

Couple pay >$800k for a gene-editing therapy for their daughter. She died.

https://www.science.org/content/article/exclusive-death-girl-chinese-gene-editing-trial-was-never-made-public
44•Shortness8•52m ago

Comments

fabian2k•13m ago
There's so many ethical problems with the events as described in the article. The worst to me seems to be that the researchers/doctors seem to have downplayed the risks here. Which for a never before tried gene therapy that is meant to work inside the brain are absolutely enormous. The ethical issues around the money seem minor in comparison with that and the fact that they seem to have ignored similar side effects in the monkey experiments.
cowlby•2m ago
Reminds me of the TGN1412 drug trial where patients had severe immune reaction and almost died. Sad that the story suggests they ignored all the signs that would suggest humans would have a bad immune reaction to it and proceeded anyway.

https://www.reddit.com/r/Documentaries/comments/jrraz7/when_...

singpolyma3•12m ago
Headline is the whole story. Sometimes a therapy doesn't work. Especially a new one
ncallaway•9m ago
> Headline is the whole story.

That's just not true.

From the article:

> According to official documents and accounts provided by the girl’s parents, the hospital had allowed Qiu’s experimental treatment to proceed under a regulatory provision that does not require approval from national regulators. After the child’s death, the hospital paid a modest fine to a local health authority but Qiu was not publicly sanctioned.

That's not in the headline, but is an important part of the story. Also from the article:

> Seven experts in fields including genetics, virology, and bioethics who reviewed details of the Nature study and the clinical trial for Science and Retraction Watch expressed concern that Qiu and his team downplayed the trial’s risks in describing them to the parents, overlooked safety signals in animal studies, and proceeded even though success was unlikely.

Also not in the headline, but also an important part of the story. Finally:

> The girl’s parents, who requested that Science use pseudonyms for them and their daughter for privacy reasons, have decided to tell her story now because they are angry about what they feel is a lack of accountability by the researchers and the institutions. “Learning the reality of these missing safeguards has fundamentally changed how we now view the entire project,” says the father, a software engineer. He asked that he be called Jason, his wife Linda, and their daughter Mei (Chinese for “beautiful”). “We did not realize how unusual and dangerous many of the arrangements were.”

Also not in the headline, also an important part of the story.

dmix•5m ago
So it was a regulatory escape hatch for highly experimental medicine and it didn't work out?

> The girl would be the first person in the world to receive a gene-editing therapy directed at the brain.

The first person to ever try something comes with risks...

ncallaway•2m ago
And were those risks adequately communicated to the people taking them? According to the story, they weren't.

That's a Big Fucking Deal, and is absolutely a significant part of the story.

Was that in the headline?

oceansky•12m ago
I can't possibly imagine what the parents are going through
Terr_•7m ago
> The paper had an enthusiastic reception. “These promising results might pave the way for the development of an effective clinical treatment,” Kevin Bender, a neuroscientist at UC San Francisco, wrote in an accompanying commentary. At the time, Bender had no idea that a girl had received it and was already dead. Meanwhile, Chinese state media, CCTV, called the work “the first ray of hope” for “countless families suffering such diseases.”

Oof, there's something deeply unjust about that, a kind of "adding insult to fatality."

People celebrating that a new treatment will save children and give hope... with no acknowledgement that it was just tried and cost you both.

cogman10•2m ago
Not to mention the part where it appears that the entire department decided to try and scam these parents.

> Jeremy Sugarman, a medical doctor and bioethicist at Johns Hopkins University, says it’s not unusual for a family to bear the costs of developing a personalized treatment. But, according to text messages shared by Jason and Linda, Qiu also asked the couple to pay other members of the research team directly, through informal arrangements they found increasingly troubling.

Qiu kept on adding on new back channel payments and seemed to keep ballooning the costs. I have to wonder if the procedure started because it was ready or because the parents ran out of resources.

fabian2k•9m ago
It's worse than that. The therapy likely killed her, and her condition wasn't fatal in the first place.