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Human brain is two separate organs, Stanford Medicine-led research finds

https://med.stanford.edu/news/all-news/2026/09/two-separate-brains.html
79•emigre•1h ago

Comments

k310•1h ago
bioRxiv preprint July 2025 [0]

The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.

[0] https://www.biorxiv.org/content/10.1101/2025.07.02.662771v2

PDF is free to download.

msephton•57m ago
Related https://www.newscientist.com/article/2589739-our-brain-evolv... https://news.ycombinator.com/item?id=49755533
bethekind•45m ago
> They identified two different brain progenitor cells. One, which expresses a gene called Otx2, is destined to become the forebrain and midbrain. The other, which expresses a gene called Gbx2, is committed to forming the hindbrain. They showed that these two cell populations never overlap; they are mutually exclusive from the earliest stages of development.

Very cool. Never thought the brain could have two completely different ancestors

trhway•17m ago
and from another post on the front page right now https://news.ycombinator.com/item?id=49735541 :

"Nervous systems are typically defined as networks of neurons that communicate across synapses. But Burkhardt’s lab found something unique in ctenophores: Beneath the animal’s outer surface is a nerve net (pink mesh in this 3D reconstruction) whose neurons are connected by continuous cytoplasm — but with no synapses between them. “I don’t think any other animal has a nervous system like that,” Burkhardt said. Because ctenophores are one of the earliest branches of the animal family tree, the finding indicates that evolution may have crafted nervous systems twice: in ctenophores, and separately in jellyfish and all other animals."

kazinator•13m ago
[delayed]
softgrow•34m ago
We are going to have to deprecate an idiom or two. "I'm in two minds about something" now gives the wrong meaning.
readthenotes1•33m ago
Not to mention the gut brain-- That's the organ I blame for the ice cream I just ate
patates•26m ago
The best way to stop eating ice cream is to stop buying ice cream. If it's in the freezer, it'll be eaten.
geuis•28m ago
This isn't peer reviewed, just a press release. 10 other "papers" will be published in the next 2 weeks counterfinding anything in this post.

Science moves forward yet again with a few backward steps.

proc0•28m ago
I can see how one of these is the gut feelings origin, and other bodily feelings.
itvision•13m ago
What a way to oversell the discovery.

The reality is:

    * Different brain regions have different functions: ancient knowledge.
    * Different regions contain distinct cell types and molecular programs: also well established.
    * Anterior and posterior brain structures may trace back to fundamentally separate progenitor lineages that were independently specified very early in evolution and development: that's the interesting new result.
The headline should have been: "Human forebrain and hindbrain arise from distinct embryonic progenitor lineages" - not that we have "two organs" in the brain.
t-writescode•7m ago
I mean, I learned a bunch of neat new stuff, so I’m excited!
sandeepkd•6m ago
Though I agree with the detailed differentiation, still for the headline purpose a generic one that resonates with people easily isn't a bad choice

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Human brain is two separate organs, Stanford Medicine-led research finds

https://med.stanford.edu/news/all-news/2026/09/two-separate-brains.html
86•emigre•1h ago•13 comments