frontpage.
newsnewestaskshowjobs

Made with ♥ by @iamnishanth

Open Source @Github

US vs. Google amicus curiae brief of Y Combinator in support of plaintiffs [pdf]

https://storage.courtlistener.com/recap/gov.uscourts.dcd.223205/gov.uscourts.dcd.223205.1300.1.pdf
224•dave1629•5h ago•306 comments

A Critical Look at MCP

https://raz.sh/blog/2025-05-02_a_critical_look_at_mcp
143•ablekh•4h ago•66 comments

Reverse engineering the 386 processor's prefetch queue circuitry

http://www.righto.com/2025/05/386-prefetch-circuitry-reverse-engineered.html
48•todsacerdoti•2h ago•17 comments

Prolog's Eternal September (2017)

https://storytotell.org/prologs-eternal-september
45•Tomte•2d ago•28 comments

The deathbed fallacy

https://www.hjorthjort.xyz/2018/02/21/the-deathbed-fallacy.html
189•mefengl•9h ago•87 comments

Sam Altman Wants Your Eyeball

https://www.privacyguides.org/articles/2025/05/10/sam-altman-wants-your-eyeball/
116•ChiptuneIsCool•3h ago•103 comments

Show HN: Code Claude Code

https://github.com/RVCA212/codesys
49•sean_•4h ago•11 comments

Comparison of C/POSIX standard library implementations for Linux

https://www.etalabs.net/compare_libcs.html
39•smartmic•4h ago•13 comments

Update turns Google Gemini into a prude, breaking apps for trauma survivors

https://www.theregister.com/2025/05/08/google_gemini_update_prevents_disabling/
35•Bender•55m ago•10 comments

Building Local-First Flutter Apps with Riverpod, Drift, and PowerSync

https://dinkomarinac.dev/building-local-first-flutter-apps-with-riverpod-drift-and-powersync
9•kobieps•3d ago•4 comments

Weave (YC W25) is hiring a founding engineer

https://www.ycombinator.com/companies/weave-3/jobs
1•adchurch•2h ago

Even Tesla's Insurance Arm Is Getting Wrecked

https://insideevs.com/news/759156/tesla-insurance-loss-higher-average/
22•ryan_j_naughton•1h ago•6 comments

Vision Now Available in Llama.cpp

https://github.com/ggml-org/llama.cpp/blob/master/docs/multimodal.md
441•redman25•15h ago•94 comments

Embracer Games Archive is preserving 75000 video games and needs contributions

https://embracergamesarchive.com/
90•draugadrotten•7h ago•45 comments

React Three Ecosystem

https://www.react-three.org/
75•bpierre•6h ago•25 comments

Private Japanese lunar lander enters orbit around moon ahead of a June touchdown

https://phys.org/news/2025-05-private-japanese-lunar-lander-orbit.html
160•pseudolus•3d ago•52 comments

LTXVideo 13B AI video generation

https://ltxv.video/
180•zoudong376•7h ago•54 comments

A simple 16x16 dot animation from simple math rules

https://tixy.land
258•andrewrn•16h ago•57 comments

Intel: Winning and Losing

https://www.abortretry.fail/p/intel-winning-and-losing
60•rbanffy•7h ago•28 comments

The Price of Remission

https://www.propublica.org/article/revlimid-price-cancer-celgene-drugs-fda-multiple-myeloma
11•danso•2d ago•1 comments

Gmail to SQLite

https://github.com/marcboeker/gmail-to-sqlite
254•tehlike•14h ago•71 comments

Show HN: Sprigman – Pac-Man Recreated in a Limited Tile Based JavaScript Engine

https://sprig.hackclub.com/share/X4EGvOFk1q8FroEPCj1G
9•kuberwastaken•2d ago•1 comments

Farewell to Lee Gold's Alarums and Excursions

https://www.chaosium.com/blogout-of-the-suitcase-54-farewell-to-lee-golds-alarums-excursions/
10•jdkee•3h ago•1 comments

Radxa Orion O6 brings Arm to the midrange PC (with caveats)

https://www.jeffgeerling.com/blog/2025/radxa-orion-o6-brings-arm-midrange-pc
70•goranmoomin•7h ago•54 comments

'We Currently Have No Container Ships,' Seattle Port Says

https://www.newsweek.com/seattle-port-says-no-container-ships-tariffs-2069464
127•pseudolus•3h ago•50 comments

Lead Bullets (2011)

https://a16z.com/lead-bullets/
6•msukkarieh•3h ago•0 comments

Loss of dance and infant-directed song among the Northern Aché

https://www.cell.com/current-biology/fulltext/S0960-9822(25)00447-6
56•PaulHoule•3d ago•9 comments

Unique Games Conjecture

https://en.wikipedia.org/wiki/Unique_games_conjecture
7•surprisetalk•2h ago•0 comments

Detect and crash Chromium bots

https://blog.castle.io/detect-and-crash-chromium-bots-with-one-weird-trick-bots-hate-it/
93•avastel•3d ago•33 comments

In praise of grobi for auto-configuring X11 monitors

https://michael.stapelberg.ch/posts/2025-05-10-grobi-x11-monitor-autoconfig/
61•secure•12h ago•14 comments
Open in hackernews

The CL1: the first code deployable biological computer

https://corticallabs.com/cl1.html
50•sprawl_•3d ago

Comments

dang•3d ago
This has been posted a few times recently and certainly looks intriguing, but as far as we can tell, there only there-there is a signup list.

For a good HN thread, we should probably wait until the product is available—or at least for more information?

Edit: looks like there was some sort of earlier discussion at:

Melbourne startup launches 'biological computer' made of human brain cells - https://news.ycombinator.com/item?id=43261218 - March 2025 (37 comments)

The comments are pretty generic, which is the sort of thread we get in the absence of more significant information, so I think waiting is probably the right call. Disagreement is welcome though!

comrade1234•1d ago
Sorry, gotta get home to feed my computer!
andrewmcwatters•1d ago
Ah man, the computer wet the desk again...
Garlef•1d ago
... and ate my homework
omneity•1d ago
"Real neurons" but whose neurons are they sourcing? And are all neurons born equal? Should we have a NeuronArena where people submit samples for eval?

@dang, agreed that the product cannot be discussed on technical merits as of now, but I suggest some of the ancillary topics (irrelevant of their technical implementation) such as neuron sourcing might be worth opening.

nine_k•1d ago
Since one batch of neurons is expected to survive "up to 6 months", there should be a way to reload it with new neurons. So neuron sourcing should be a recurring concern. The site says: «Real neurons are cultivated inside a nutrient rich solution, supplying them with everything they need to be healthy. They grow across a silicon chip»; this seems to mean that replacing the neurons would require special skills and knowledge, and maybe even a service contract.
throwanem•1d ago
See those three fluid inlets on the back in the render? Or what look a lot like quick-disconnect hose fittings, at least, and no wonder; this is among other things a life support system for brain tissue, and will minimally need to maintain hydration and exhaust waste. Operating the machine at all will certainly require engineering and environmental services only feasibly available in a professionally staffed and maintained laboratory.

That is one of the reasons why the "buy" CTA dispatches to a contact form. They can and must vet potential customers.

nine_k•1d ago
Yes, this is a given. I mean that replacing neurons may require a specific knowledge of this machine, and procedures unique to it.

If I were to create such a machine, I'd make the whole top part replaceable, with the bottom part electronic-only. When your neuron culture runs its course, you detach the top part and ship it back to the maker, and buy a new one, with a fresh culture, at a discount. They recycle the top parts by cleaning them and re-populating them with new neurons. The sourcing liability is on them, as is quality control.

genpfault•1d ago
> the first code deployable biological computer

First? C'mon, Anodyne was doing this back in the mid-80s[1]!

[1]: https://www.mysteryfleshpitnationalpark.com/post/63769988673...

throwanem•1d ago
Hey, I recognize that robot! That was the Heathkit, wasn't it?
andrewmcwatters•1d ago
Isn't it weird that they don't actually show what you can do with it?

I mean, I guess they have some capabilities mentioned in papers a few pages back in their website, but it doesn't pass the skink test of, "OK, show me how it works."

IDK, give me an actual code snippet right on the front page, or shut up.

I'm obviously not the target audience, but their marketing is aligned with the sort of "we made this look pretty because we want as many people remotely interested as possible to buy this thing."

Otherwise it could have been a lot more plain, and people seeking out this sort of technology would have found it.

InsideOutSanta•23h ago
From the website:

> In vitro neurons learn and exhibit sentience when embodied in a simulated gameworld

I can't tell if this whole thing is an art project or a real product.

fuentesjr•23h ago
Also covered in https://www.youtube.com/watch?v=txtDpCLHUkU
WorkerBee28474•23h ago
We got bio-neural gel packs before GTA 6. Or Half Life 3.
Aaronstotle•23h ago
Very interesting, I had to re-read it a few times to make sure it was real and not some elaborate prank. I actually wrote a Philosophy paper where there was a computer that had a biological component, and this is almost exactly what I had in mind, very neat to see that there is a company out there making it.
smrtinsert•22h ago
What in the black mirror...
Proofread0592•21h ago
Can't wait for the inevitable "this blog is hosted on human brain cells" HN post when someone actually gets their hands on one of these.
jarbus•20h ago
I can't tell how much computing power this machine has
skulk•15h ago
The Thought Emporium, a YouTube channel, has some videos that demonstrate how something like this could be built:

Growing Rat neurons to play DOOM (unfinished): part 1 -- https://www.youtube.com/watch?v=bEXefdbQDjw; part 2 -- https://www.youtube.com/watch?v=c-pWliufu6U

Growing human neurons: https://www.youtube.com/watch?v=V2YDApNRK3g