It is my understanding that we have tried anti inflammatory interventions and they didn’t help. So the conclusion that inflammation per se is not the problem seems to check out.
amelius•2h ago
Are you sure the side effects of the interventions were not the problem?
k__•2h ago
I dimmly remember Japanese research about how fasting induced autophagy could help.
elcritch•7m ago
There’s dozens of pro-inflammatory signaling proteins. Our anti-inflammatories really only target a small subset of them.
Ideally you need to stop inflammatory signals at the source, but we understand very few of those.
kpmcc•2h ago
If anyone wants an interesting read on inflammation / stress for lay audiences, I'd recommend 'Why Zebras Don't Get Ulcers' by Sapolsky.
adrianN•3h ago
amelius•2h ago
k__•2h ago
elcritch•7m ago
Ideally you need to stop inflammatory signals at the source, but we understand very few of those.