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Local-first software (2019)

https://www.inkandswitch.com/essay/local-first/
500•gasull•7h ago•150 comments

Cod Have Been Shrinking for Decades, Scientists Say They've Solved Mystery

https://www.smithsonianmag.com/smart-news/these-cod-have-been-shrinking-dramatically-for-decades-now-scientists-say-theyve-solved-the-mystery-180986920/
30•littlexsparkee•3h ago•10 comments

Europe's first geostationary sounder satellite is launched

https://www.eumetsat.int/europes-first-geostationary-sounder-satellite-launched
146•diggan•7h ago•30 comments

Optimizing Tool Selection for LLM Workflows with Differentiable Programming

https://viksit.substack.com/p/optimizing-tool-selection-for-llm
6•viksit•1h ago•1 comments

Atomic "Bomb" Ring from KiX (1947)

https://toytales.ca/atomic-bomb-ring-from-kix-1947/
34•gscott•3d ago•5 comments

Speeding up PostgreSQL dump/restore snapshots

https://xata.io/blog/behind-the-scenes-speeding-up-pgstream-snapshots-for-postgresql
62•tudorg•5h ago•8 comments

macOS Icon History

https://basicappleguy.com/basicappleblog/macos-icon-history
83•ksec•6h ago•22 comments

X-Clacks-Overhead

https://xclacksoverhead.org/home/about
177•weinzierl•3d ago•34 comments

The Prime Reasons to Avoid Amazon

https://blog.thenewoil.org/the-prime-reasons-to-avoid-amazon
86•DanAtC•1h ago•41 comments

The Moat of Low Status

https://usefulfictions.substack.com/p/learn-to-love-the-moat-of-low-status
325•jger15•3d ago•137 comments

Seine reopens to Paris swimmers after century-long ban

https://www.lemonde.fr/en/france/article/2025/07/05/seine-reopens-to-paris-swimmers-after-century-long-ban_6743058_7.html
76•divbzero•4h ago•39 comments

Haskell, Reverse Polish Notation, and Parsing

https://mattwills.bearblog.dev/haskell-postfix/
26•mw_1•3d ago•5 comments

The Calculator-on-a-Chip (2015)

http://www.vintagecalculators.com/html/the_calculator-on-a-chip.html
11•Bogdanp•5h ago•0 comments

WinUAE 6.0.0 Amiga Emulator

https://www.winuae.net/
9•doener•55m ago•0 comments

Pet ownership and cognitive functioning in later adulthood across pet types

https://www.nature.com/articles/s41598-025-03727-9
27•bookofjoe•2h ago•10 comments

Gecode is an open source C++ toolkit for developing constraint-based systems (2019)

https://www.gecode.org/
58•gjvc•13h ago•13 comments

Build Systems à la Carte (2018) [pdf]

https://www.microsoft.com/en-us/research/wp-content/uploads/2018/03/build-systems.pdf
64•djoldman•3d ago•16 comments

Is It Cake? How Our Brain Deciphers Materials

https://nautil.us/is-it-cake-how-our-brain-deciphers-materials-1222193/
10•dnetesn•2d ago•3 comments

Just Ask for Generalization (2021)

https://evjang.com/2021/10/23/generalization.html
31•jxmorris12•2d ago•3 comments

QSBS Limits Raised

https://www.mintz.com/insights-center/viewpoints/2906/2025-06-25-qsbs-benefits-expanded-under-senate-finance-proposal
44•tomasreimers•10h ago•19 comments

Optimizing typography of insect labels using free fonts and free software (2012) [pdf]

https://www.akentsoc.org/doc/Bowser_ML_2012.pdf
23•exvi•3d ago•2 comments

Parametric shape optimization with differentiable FEM simulation

https://docs.pasteurlabs.ai/projects/tesseract-jax/latest/examples/fem-shapeopt/demo.html
6•dionhaefner•2d ago•0 comments

The History of Electronic Music in 476 Tracks (1937–2001)

https://www.openculture.com/2025/06/the-history-of-electronic-music-in-476-tracks.html
104•bookofjoe•2d ago•36 comments

What 'Project Hail Mary' teaches us about the PlanetScale vs. Neon debate

https://blog.alexoglou.com/posts/database-decisions/
29•konsalexee•10h ago•48 comments

Being too ambitious is a clever form of self-sabotage

https://maalvika.substack.com/p/being-too-ambitious-is-a-clever-form
625•alihm•1d ago•179 comments

Problems the AI industry is not addressing adequately

https://www.thealgorithmicbridge.com/p/im-losing-all-trust-in-the-ai-industry
158•baylearn•11h ago•170 comments

EverQuest

https://www.filfre.net/2025/07/everquest/
262•dmazin•1d ago•148 comments

Telli (YC F24) Is Hiring Engineers [On-Site Berlin]

https://hi.telli.com/join-us
1•sebselassie•15h ago

Incapacitating Google Tag Manager (2022)

https://backlit.neocities.org/incapacitate-google-tag-manager
207•fsflover•1d ago•143 comments

A 37-year-old wanting to learn computer science

https://initcoder.com/posts/37-year-old-learning-cs/
135•chbkall•13h ago•131 comments
Open in hackernews

Heart attacks aren't as fatal as they used to be

https://www.vox.com/future-perfect/418849/heart-attack-deaths-cardiovascular-disease-progress-medicine
63•lr0•6h ago

Comments

oncallthrow•5h ago
The article should really have a picture of a cath lab at the top, not an AED. Advances in catheterization technology are the key factor in reducing heart attack deaths, not AEDs
deadbabe•5h ago
Explain
AnimalMuppet•5h ago
There is a procedure called a "catheterization" (hence "cath lab").

I have two stents in my heart. They went in with a catheter through an artery in my wrist. They found the places in my heart where the arteries were 80% to 90% blocked, and placed stents there. They said I was five years from a heart attack.

This was an outpatient procedure. I went home that night.

The worst part of it, for me, was that they put a serious tourniquet on my wrist, because once they took the catheter out, I had an open artery. My wrist felt like I lost a bar fight. It ached for a month.

This is so much better than having a heart attack.

How did they know I needed this? I talked to a cardiologist. He told me that, as you age, your athletic performance drops slowly, over decades. That's normal. What's abnormal is when you suddenly can't do something you were able to do a month ago.

So I paid attention when I realized, hey, a month ago I didn't get this winded playing ultimate frisbee. A month ago I recovered faster when I was winded.

So I told that to my GP. He ordered a cardiac stress test for me. This basically is hooking you up to an EKG, putting you on a treadmill, running the treadmill faster and harder until you drop, and watching what your EKG does. If the shape stays the same except faster, you're good. If the shape changes, that's part of your heart not getting enough blood under load. My shape changed. So they ordered the catheterization for me.

So cath labs are about preventing the heart attack, not keeping you from dying once you have one. Not dying is good. But not having it at all is better. I think that may have been the GP's point.

khuey•3h ago
> So cath labs are about preventing the heart attack, not keeping you from dying once you have one.

Cath labs *are* (also) about keeping you from dying once you have one. Inserting a stent into someone with an active MI can restore blood flow and minimize tissue damage.

duskwuff•2h ago
Catheterization is the mode of access to the heart, not the entire procedure. Stenting is one procedure that can be carried out that way, but there are other procedures which can be performed that way as well, such as imaging, cardiac ablation, pacemaker or defibrillator installation, or valve replacement.
pfannkuchen•5h ago
Which part needs to be explained? I think I understood the comment and I’m not in the industry. AED is an initialism for the electrical shock device you can use to (maybe) reboot the heart’s OS when it locks up. Catheters are some kind of tube that gets implanted to bypass a non-functional part of the heart. Catheter procedures improving caused the change, not AEDs (apparently), so it’s somewhat misleading to show an AED instead of something about catheters.
roryirvine•5h ago
PCI (Percutaneous Coronary Intervention, performed in a catheterization laboratory) has become the usual first-line treatment for acute heart attacks.

It's much more effective than previous treatments (essentially clot-busting drugs, blood thinners, and bedrest), particularly since Drug-Eluting Stents arrived in the early 2000s.

FireBeyond•4h ago
Critical care paramedic here. The answer is "both".

AEDs are a key factor in ensuring patient survival until we can get them to the cath lab and get them ballooned.

"High quality compressions, early access to defibrillation". For every minute you do not have an effective pulse, your chance of survival goes down about 10%.

Airway management takes a distant back seat. Most meds we give are only mildly, or questionably effective.

But being able to defibrillate a dysrhythmia early is the key to getting the heart working itself - chest compressions are the best we have, but still. It takes us minutes of compressions to get to a suitable arterial pressure for effective perfusion, but ten seconds or less to lose it.

AEDs won't improve volume and arterial flow, but it'll give you a fighting chance of getting to the lab. Compressions alone are not going to do that - they will just preserve tissue.

pipes•4h ago
What are AEDs? Aspirin? Blood thinners? I'm from the UK, so probably a naming difference!
Eavolution•3h ago
AED: Automatic External Defibrillator, a defibrillator that doesn't need a trained operator

Aspirin: a blood thinner and painkiller

Blood thinners: given to people at risk of a heart attack to thin the blood and reduce the chance of blood flow being obstructed

5555624•3h ago
AED - Automated External Defibrillator. They're portable device defibrillator which can deliver an electric shock. As I understand it, it detects an abnormal heart rhythm and shocks the rhythm back to normal. Note that there are some situations where they will not work. (For example, Pulseless Electrical Activity or PEA is "non-shockable.")
dreamcompiler•1h ago
Correct. The shockable rhythms are ventricular fibrillation and ventricular tachycardia (racing heart). Fortunately these rhythms occur in many heart attacks.

Unfortunately PEA and asystole (flatline) do too, and shocking won't fix those -- despite what movies and TV would often have you believe.

FireBeyond•1h ago
Precisely. Well, when you're talking about AEDs - VF and VT.

Defib is more like rebooting a malfunctioning heart, versus jump starting it.

Paramedics with a manual defibrillator can do other things with other rhythms, but AEDs are limited to those.

5555624•1h ago
> despite what movies and TV would often have you believe.

Yeah, I found out the hard way, suffering PEA. AEDs are great; but, people should still learn CPR.

khuey•3h ago
IIRC in the King's English:

aspirin = acetylsalicylic acid

blood thinners = anticoagulants

oncallthrow•8m ago
They are called AEDs in the UK too
paulpauper•5h ago
Yeah cancer is the big killer nowadays. Survival rates for stage 4 cancer still poor after many decades of research. Worse yet, in many instances there are no obvious risk factors, such as people in their 30s or 40s who get colon cancer and were not eligible for screening .
yieldcrv•5h ago
that’s to be expected, after we do the adequate screening for one older population and mitigate many of the advanced versions of that, then the previously edge case becomes more prevalent amongst all cases

there is still a limited resource for the screening at this point, so that’s a friction to expanding screening

zahlman•5h ago
It's not just a question of scaling up the screening effort. Doctors are also concerned with potential harms caused by false positives.
greedo•4h ago
What false positive would come out of a colonoscopy? You are visually looking for masses, and removing suspect polyps that are sent in for evaluation. The major potential harm of a colonoscopy is a bowel perforation. Serious complications occur roughly 0.3% of the time.
Someone•4h ago
> Serious complications occur roughly 0.3% of the time.

https://www.cancer.org/cancer/types/colon-rectal-cancer/abou..., “the lifetime risk of developing colorectal cancer is about 1 in 24 for men and 1 in 26 for women.”

So, it’s a 4% lifetime risk versus a 0.3% per colonoscopy risk. The outcomes for the two risks also are different, but I would think that for many healthy people (e.g. those under 40 years old), the risk of doing such a check are greater than that of not taking it.

Reading https://en.wikipedia.org/wiki/Colorectal_cancer#Screening, that’s one of the reasons frequent colonoscopies aren’t advised.

accrual•5h ago
> not eligible for screening

Is this a thing? I thought I could walk into my PCP's office and schedule a screening any time, provided I may need to pay more out of pocket or something.

BobbyTables2•5h ago
PCP is certainly not going to be the one doing the colonoscopy.

maybe they’d do the stool sample or some silly blood test if you are extremely insistent and can somehow demonstrate a risk factor.

I’ve dealt with a few PCPs and they seem less informed about their own area than a 30 sec google search.

They’re basically L6 tech support…

exhilaration•4h ago
I read here (on Hacker News) that the stool test is actually really valuable and cheap enough to pay out of pocket prior to trying to justify an out-of-schedule colonoscopy.
OptionOfT•3h ago
Not to mention the prepare for a colonoscopy is not pleasant.
SoftTalker•3h ago
And colonoscopies are invasive procedures that have their own risks. Perforated bowel can turn this "routine" procedure into an emergency.
TimorousBestie•5h ago
Colonoscopies here (midwestern US) are upwards of a couple thousand outside of the usual schedules enforced by insurance companies.

If there’s a complication they can easily skyrocket into the tens of thousands.

Most people around here can’t soak that.

adwi•4h ago
Grandfather died of colon cancer at 43.

Went into my PCP at 40 asking for a colonoscopy, he said insurance wouldn’t cover it until I was 50.

…

giardini•4h ago
Ask him to do a hemoccult (done in the office - doc sticks his finger up your a** and dabs it on a test material) or request a cologuard test (shit in a box at home and mail it to the lab! - loads of laughs driving cautiously to FEDEX!)

The hemoccult (FIT or FOBT) tests are <$100 and the cologuard ~$700. Your insurance will likely cover (esp. the hemoccult test) all the more if you tell doctor of your family background. Hemoccult tests were part of my routine annual physical for decades and there are no familial tendencies.

There are some caveats: e.g., avoid bloody foods in the days preceding these test (Chinese pigs' blood cubes, yummm!)

gosub100•2h ago
You shouldn't have to do this, but have you tried calling the colonoscopy practice and asking for a cash price? It might not be as expensive as you think.
SoftTalker•3h ago
Screenings are not risk-free. There are always some false positives which then may lead to more invasive and unnecessary tests or treatment. There are a lot of rare conditions (based on age and/or history) that we don't screen for on a routine basis.
tonyedgecombe•5h ago
Would screening improve the outcomes or just create more patients getting unnecessary treatment?
greedo•4h ago
Catching colorectal cancer at an early stage improves survival rates tremendously. You have to weigh the risk of complications from the colonoscopy (primarily bowel perforation) with the improved outcomes. There's a cost element as well, since colonoscopies (without complications) can be several thousand dollars.
ak217•4h ago
Yes, colorectal cancer screening is estimated to reduce colorectal cancer mortality by 50% to 73%.

https://pmc.ncbi.nlm.nih.gov/articles/PMC10093633/

https://www.nejm.org/doi/full/10.1056/NEJMoa2208375

Progressive screening using non-invasive assays like Cologuard and FIT is a valuable screening mode. The non-invasive assays are not perfect but they are improving.

lostmsu•1h ago
What about overall mortality?
jvanderbot•5h ago
My father didn't die of a heart attack, he died of an aneurysm. However, he had a massive "widow maker" heart attack and had to be revived from arrest in the ER, more than once.

He had a heart beat, unconscious, for a few days, before the blood thinners caused the aneurysm, I'm told.

So, is this a heart attack? Is this "less deadly?" No, it's a proximal classification. Maybe their cardiac care center has a metric to hit.

VeninVidiaVicii•5h ago
Anecdotally I worked in the emergency department and ICU for 2.5 years as a scribe and translator in undergrad (ending about 7 years ago) and never saw a single person successfully revived. In the sense that everybody who ever got revived to the point that your dad did, in my experience, died.
mv•4h ago
this is why american medical care is so expensive. Family’s and Law make doctors “do everything” even when the doctors know there is 0.01% chance such a person even makes it out of the icu and that’s not saying anything about brain function.
golergka•3h ago
IMO it's still good that it's family's decision. Even if it is an incorrect one.
KittenInABox•3h ago
I think its good, but I also think that we don't have enough education in the US populace about what this means realistically. "Pulling out all the stops" means that your loved ones last time on this earth is either in agony or comatose, neither of which I would tolerate of my dog much less my mother.
kzrdude•3h ago
The biggest reason is probably that you need to fit a medical insurance agent, a lawyer and a doctor all around the same hospital bed to give care.
Jare•2h ago
I'm pretty sure that in "socialized medicine" countries i.e. the rest of the civilized world pretty much, they also "do everything" even if chances are low. AND everyone involved (including family) can do their part in it without having to deal with papers, money, bills, proof of insurance, and the plethora of other likely speed bumps that exist in the US.

So no, I don't think that's why. If anything, the amount and quality of average care for the average US citizen is lower, if life expectancy and my anecdotal observation are valid indicators.

It's expensive because it's a business designed to make profit every step of the way, and over time has created many steps to feed.

gosub100•2h ago
Even if they die, reviving them still opens the door for organ and tissue donation.
Calavar•2h ago
Off the top of my mind, I can think of two patients who I personally cared for in the days or weeks after CPR who had an outcome other than death or vegetative state. One patient walked out the door two weeks after admission. The other patient regained consciousness and was able to speak/communicate, but was bed bound, appeared to have sustained some degree of cognitive damage, and had to receive feeds through a gastric tube. She was in the hospital for about six months before being discharged to a nursing facility. That's the numerator. It's hard to quantify the denominator. 40 or 50 maybe? But that's a guess.
mr_toad•2h ago
> heart attack and had to be revived from arrest

Worth pointing out that heart attacks and cardiac arrest are not the same. A heart attack (myocardial infarction) is insufficient supply of blood to the heart, which causes damage. Cardiac arrest is when the heart stops completely (and is much more serious).

Heart attacks can cause cardiac arrest (especially if not treated), but the most common outcome is not immediate death. With proper treatment maybe 95% of MCI patients will survive. The prognosis for cardiac arrest is much worse - ~90% of patients experiencing a cardiac arrest will not survive, even if temporarily revived.

dreamcompiler•2h ago
Out-of-hospital arrests are that deadly. Those that occur in a hospital are somewhat more survivable.

Not a whole lot more, but if you're going to arrest you want to do it in a hospital with lots of nurses nearby.

DarknessFalls•2h ago
Many heart attacks occur because people don't get enough exercise and overeat. This is often the result of clinical depression. Is the killer depression or is it heart disease?

Same with the hyperlipidemia. It leads to eventual plaques in the arteries, which leads to heart attacks. But that's a genetic abnormality in the liver. The liver is pulling the trigger, the heart is taking the bullet.

kelseyfrog•4h ago
No doubt a decrease of smoking, availability of satins, cpr/defibrillators, and stents has led to a massive increase in prevention and survival.

However, the diagnostic and treatment side has improved considerably in that time too. Troponin assays became widely available in the late 1990s/early 2000s, and dual antiplatelet therapy (aspirin + clopidogrel) around 2000s. These are part of the standard toolkit for detecting and treating MIs that simply didn't exist when I was young and are part of the story of making MIs catastrophic events to a more survivable disease.

The article isn't wrong per se, but I do want to point out that it isn't comprehensive when it comes to listing the reasons. There are interesting advances that it left out.

tuatoru•4h ago
Your point generalises. For instance, homicide rates have fallen in large part because many wounds that used to be fatal are now survived. Breast cancer death rates also are down because of better diagnosis and treatment.
nurettin•34m ago
And transportation, electronic communication, beta blockers, blood diluters...
exhilaration•4h ago
I would just like to recommend this excellent Radiolab episode about saving lives during heart attacks: https://radiolab.org/podcast/how-to-save-a-life
thro230-0•4h ago
Also as result of long covid, more young healthy people get hearth attack. They have better chance to survive hearth attack, than older people. It improves survival stats!
southernplaces7•4h ago
I as a relatively young man also hate it when my hearth is attacked. One can't even be secure before their own fireplace, in their own home any more.

Hearth= area in home where fire is kept, usually for cooking.

Heart= that sometimes unfortunate little knot of pumping muscle under your rib cage.

rectang•3h ago
> A sudden cardiac death is the disease equivalent of homicide or a car crash death. It meant someone’s father or husband, wife or mother, was suddenly ripped away without warning.

Now ever increasing numbers of people avoid an abrupt death and live long enough that misery and terrible quality of life extend for decades. Hooray for all of those who emphasize preventing death above all else, whether they are motivated by extracting medical fees during life's long slow twilight, or by more pure considerations.

mr_toad•2h ago
Most people who recover from a heart attack will not suffer a terrible quality of life. Depending on the severity and the treatment many will live quite normal lives for decades, and die from something completely unrelated.
dreamcompiler•2h ago
CAC tests are not without risk. Every CAC test is a CAT scan which means X-ray radiation.

It is certainly the case that for a great many people the benefits of a CAC test outweigh the risks, but talk to your doctor before you rush out and get one.

I wish it were possible to do a CAC test using MRI (and thus without ionizing radiation) but to the best of my knowledge it's not.

Razengan•22m ago
Wish it was the case for some of my family :(