Scientists may have found a way to eliminate chromosome linked to Down syndrome

https://academic.oup.com/pnasnexus/article/4/2/pgaf022/8016019

149•MattSayar•3h ago•69 comments

Graphene OS: a security-enhanced Android build

https://lwn.net/SubscriberLink/1030004/898017c7953c0946/

73•madars•3h ago•13 comments

Inter-Planetary Network Special Interest Group

https://www.ipnsig.org

89•OhMeadhbh•4h ago•20 comments

Positron – A next-generation data science IDE

https://positron.posit.co/

90•amai•3d ago•42 comments

New Aarch64 Back End

https://ziglang.org/devlog/2025/#2025-07-23

53•Bogdanp•3h ago•5 comments

I wasted weeks hand optimizing assembly because I benchmarked on random data

https://www.vidarholen.net/contents/blog/?p=1160

210•thunderbong•3d ago•64 comments

There is no memory safety without thread safety

https://www.ralfj.de/blog/2025/07/24/memory-safety.html

249•tavianator•9h ago•229 comments

AMD CEO sees chips from TSMC's US plant costing 5%-20% more

https://www.bloomberg.com/news/articles/2025-07-23/amd-ceo-su-sees-chips-from-us-tsmc-plant-costing-5-to-20-more

240•mfiguiere•1d ago•425 comments

A GPU Calculator That Helps Calculate What GPU to Use

https://calculator.inference.ai/

33•chlobunnee•2h ago•10 comments

Visa and Mastercard: The global payment duopoly (2024)

https://quartr.com/insights/edge/visa-and-mastercard-the-global-payment-duopoly

198•bilekas•3h ago•89 comments

Revisiting Moneyball

https://djpardis.medium.com/revisiting-moneyball-074fc2435b07

49•sebg•3h ago•10 comments

Why concatenative programming matters (2012)

http://evincarofautumn.blogspot.com/2012/02/why-concatenative-programming-matters.html

44•azhenley•3d ago•7 comments

PSA: SQLite WAL checksums fail silently and may lose data

https://avi.im/blag/2025/sqlite-wal-checksum/

234•avinassh•10h ago•111 comments

RE#: High performance derivative-based regular expression matching (2024)

https://arxiv.org/abs/2407.20479

12•fanf2•3d ago•1 comments

Air Force unit suspends use of Sig Sauer pistol after shooting death of airman

https://www.nhpr.org/nh-news/2025-07-23/sig-sauer-pistol-air-force-shooting-death

87•duxup•6h ago•149 comments

Use Your Type System

https://www.dzombak.com/blog/2025/07/use-your-type-system/

220•ingve•10h ago•218 comments

Vet is a safety net for the curl | bash pattern

https://github.com/vet-run/vet

174•mooreds•12h ago•161 comments

Intel CEO Letter to Employees

https://morethanmoore.substack.com/p/intel-ceo-letter-to-employees

161•fancy_pantser•4h ago•285 comments

Open Source Maintenance Fee

https://github.com/wixtoolset/issues/issues/8974

209•AndrewDucker•12h ago•151 comments

Covers as a way of learning music and code

https://ntietz.com/blog/covers-as-a-way-of-learning/

120•zdw•3d ago•66 comments

Superfunctions: A universal solution against sync/async fragmentation in Python

https://github.com/pomponchik/transfunctions

22•pomponchik•3d ago•23 comments

American sentenced for helping North Koreans get jobs at U.S. firms

https://fortune.com/2025/07/24/north-korean-it-workers-chapman-nike/

90•fortran77•4h ago•62 comments

Bus Bunching

https://www.futilitycloset.com/2025/07/12/bus-bunching/

47•surprisetalk•4d ago•54 comments

UK: Phone networks down: EE, BT, Three, Vodafone, O2 not working in mass outage

https://www.the-independent.com/tech/ee-bt-three-vodafone-o2-down-phone-networks-outage-latest-b2795260.html

187•oger•11h ago•81 comments

Mwm – The smallest usable X11 window manager

https://github.com/lslvr/mwm

122•daureg•3d ago•50 comments

Writing is thinking

https://www.nature.com/articles/s44222-025-00323-4

258•__rito__•3d ago•110 comments

The POSIX specification of vi

https://pubs.opengroup.org/onlinepubs/9799919799/utilities/vi.html

58•exvi•3d ago•18 comments

Show HN: Easy Python Time Parsing

https://github.com/felixnext/python-time-helper

14•felixnext•3d ago•2 comments

Thunder Compute (YC S24) Is Hiring a C++ Systems Engineer

https://www.ycombinator.com/companies/thunder-compute/jobs/DhML6Uf-c-systems-engineer

1•cpeterson42•13h ago

Building MCP servers for ChatGPT and API integrations

https://platform.openai.com/docs/mcp

47•kevinslin•4h ago•19 comments

Scientists may have found a way to eliminate chromosome linked to Down syndrome

Graphene OS: a security-enhanced Android build

Inter-Planetary Network Special Interest Group

Positron – A next-generation data science IDE

New Aarch64 Back End

I wasted weeks hand optimizing assembly because I benchmarked on random data

There is no memory safety without thread safety

AMD CEO sees chips from TSMC's US plant costing 5%-20% more

A GPU Calculator That Helps Calculate What GPU to Use

Visa and Mastercard: The global payment duopoly (2024)

Revisiting Moneyball

Why concatenative programming matters (2012)

PSA: SQLite WAL checksums fail silently and may lose data

RE#: High performance derivative-based regular expression matching (2024)

Air Force unit suspends use of Sig Sauer pistol after shooting death of airman

Use Your Type System

Vet is a safety net for the curl | bash pattern

Intel CEO Letter to Employees

Open Source Maintenance Fee

Covers as a way of learning music and code

Superfunctions: A universal solution against sync/async fragmentation in Python

American sentenced for helping North Koreans get jobs at U.S. firms

Bus Bunching

UK: Phone networks down: EE, BT, Three, Vodafone, O2 not working in mass outage

Mwm – The smallest usable X11 window manager

Writing is thinking

The POSIX specification of vi

Show HN: Easy Python Time Parsing

Thunder Compute (YC S24) Is Hiring a C++ Systems Engineer

Building MCP servers for ChatGPT and API integrations

Scientists may have found a way to eliminate chromosome linked to Down syndrome

Graphene OS: a security-enhanced Android build

Inter-Planetary Network Special Interest Group

Positron – A next-generation data science IDE

New Aarch64 Back End

I wasted weeks hand optimizing assembly because I benchmarked on random data

There is no memory safety without thread safety

AMD CEO sees chips from TSMC's US plant costing 5%-20% more

A GPU Calculator That Helps Calculate What GPU to Use

Visa and Mastercard: The global payment duopoly (2024)

Revisiting Moneyball

Why concatenative programming matters (2012)

PSA: SQLite WAL checksums fail silently and may lose data

RE#: High performance derivative-based regular expression matching (2024)

Air Force unit suspends use of Sig Sauer pistol after shooting death of airman

Use Your Type System

Vet is a safety net for the curl | bash pattern

Intel CEO Letter to Employees

Open Source Maintenance Fee

Covers as a way of learning music and code

Superfunctions: A universal solution against sync/async fragmentation in Python

American sentenced for helping North Koreans get jobs at U.S. firms

Bus Bunching

UK: Phone networks down: EE, BT, Three, Vodafone, O2 not working in mass outage

Mwm – The smallest usable X11 window manager

Writing is thinking

The POSIX specification of vi

Show HN: Easy Python Time Parsing

Thunder Compute (YC S24) Is Hiring a C++ Systems Engineer

Building MCP servers for ChatGPT and API integrations

Optery (YC W22) Is Hiring in Engineering, Legal, Sales, Marketing (U.S., Latam)