With a 4K display the pixel density is high enough that virtually everything looks good scaled this way, though once you go higher than SD content you're usually dealing with 720p and 1080p, both of which 2160p divides into evenly anyway.
It's surprising how often I see bad pixel art scaling given how easy it is to fix.
Single bilinear samples can lose information and leave out pixels of the higher res image, it's essentially a worse triangle filter.
jan_Inkepa•5h ago
Here's a related disucssion on what 'pixelated' should mean from the css working group
https://github.com/w3c/csswg-drafts/issues/5837
(every so often browsers break/rename how nearest-neighbouring filtering works. I hope at some point it stabilizes lol - I note in the discussion linked nobody else cares about backwards compatibility ...).