Also don't forget you can couple your psychedelics with valium. (This isn't medical advice)
The acronym WEIRD stands for Western, Educated, Industrialized, Rich, and Democratic, a term used in psychology and behavioral sciences to describe the populations that have historically been the subject of research.
If you are deeply curious about these types of drugs, you need to remember that they all wear off eventually. Lots of very smart and happy people have taken these drugs and experienced no harm.
I'm willing to believe, though, that some people might know how to guide a person through the experience in such a way as to drastically reduce the risk of PTSD and to increase the probability of beneficial effects.
Also, I'm willing to believe that they can help a person recover from PTSD, too, but that is not what usually happens when they are taken without supervision.
This is somewhere between "False" and "So misleading about an astronomically small risk that we should just treat it as False".
Driving or riding in a car is a more likely cause of PTSD - you might be involved in a horrific crash.
Nothing in this world is risk free, but if we dropped the cultural stigma and history, and these were just discovered by Pfizer today and went through regular FDA processes, this class of drugs would have a risk profile lower than SSRIs, benzodiazepines, and most other drugs used for psychiatric purposes.
The harm is much more apparent to observers than it is to the psychedelic user him or herself.
Tales of people's lives and level of function steeply declining after taking a psychedelic, then staying that way for years, are not exactly rare.
Because sometimes that is the last thing that's left. When everything else has failed it may be the only hope that stands between you and the abyss.
We only live once.
If your default live model is going to school, then going to unviersity, partner, kids, work, work, living daily live, getting old, dying and you are happy and content, great!
But that image is not true for a lot of people for a lot of different rasons.
LSD gave me a lot of empathy for people who have some mental illness for example. MDMA gave me a very empathic experience i never had before.
And just getting old might be a goal for people, also something like not dying but again, thats just a default thinking not necessarliy what other people conclude for their lives.
The reason I took psychedelics the first time was also some combination of curiosity, recreation, and frustration at feeling like I'd fallen into a local min. As a cousin comment mentions, their power is giving you a different perspective which you quite literally cannot conceive of in your current mental state.
Those who have been to therapy (and had a good therapist) know the value that an honest and different outside perspective can have on your life. But there's also a barrier between you and that other person - they don't really have the full context of what motivates or worries you. Psychedelics are a new perspective on the thoughts going through your head, the sensory experience you're having, the emotions you're physically feeling.
That's not to say it's all good and no bad, but I'll leave that to the droves of comments exaggerating their risks. If you're looking for an altered mental state, mushrooms / LSD / MDMA pose far less harm than alcohol or cannabis.
As a mathematician I can assure you that the feeling of understanding is an emotion. It's mostly disconnected from truth/false values. People can be emotionally happy, be exited and have a group feeling of understanding - but then you give them a counterexample and it turns out everything was just wrong.
A drug might be able to trigger the emotions, but the things about deeper understandings are most likely just illusions. I think I understood that when some guy who was a very simple mind (he was into sniffing glue - and bummed for alcohol) told me about his wonderful experiences of understanding the world.
But I think your concern about negative fundamental modification seems higher than the reports suggest it ought to be. There are thousands upon thousands of people who've used these drugs without serious consequence. I'd say that in general they're less of a concern than alcohol.
Here's one link I found supporting my intuition: https://www.psypost.org/scientists-say-psychedelic-drugs-lik...
The feeling is fantastic, nothing like weed or booze. You feel relaxed and warm in the sense that you want to be around people and talk to people. Like it fills you with love for humanity (I wanted to call my mother and tell her I loved her and so on.) BUT it makes you hyper aware of emotions so be sure your environment is relaxed if you're inexperienced. As you come down you will then start to wrestle with your own buried emotions which can really be a roller coaster. However, as long as the environment is relaxed you will feel safe and be able to handle them.
The trick is go slow for your first time, take a little and see how you feel as it take 30-45 min to kick in (for me 45 min like clock work almost.) Make sure you are in a good mental state. Had a bad week or something really bothering you? Not a good state. Don't trip. Make sure the environment feels safe and relaxed.
I’ve been taking doses of around 600mg ibogaine TA, every 6 months or so, bought online at the first place that comes up in google. You can experience cardiac arrest from taking it, which will quickly kill you, and I based this (IMO) safe dosage on some papers I read. Don’t consider me an authority! And there’s also certain gene mutations that can raise or lower your risk of heart problems, related to how you metabolize ibogaine/noribogaine.
(I have also tried microdosing, based on another paper I read about a woman with bipolar depression. But I don’t have much to report there.)
It’s tough to describe any altered state. But for someone who’s thinking it’s like acid or mushrooms, note that it’s not really fun or pleasant. Your heart beats slower and softer, your body feels weak and uncoordinated, and there’s little to do besides rest.
But the mind is so, so active. And it’s like an excavator. Just pulling things from wherever and throwing them into your mind’s eye. I don’t like therapy and find it tedious and unhelpful, but this feels like years of therapy squished into a 12+ hour trip. Has helped me a lot with my relationships, especially with my mom.
You see a lot of yourself. What’s ugly, what’s beautiful, what’s neutral. You feel somehow distant from your problems but close to your “self”, which makes it more comfortable to face things.
After it’s over there’s a glow and calm that lasts a while. Days, or weeks, or months sometimes. Sleep feels a little more restorative, laughs come a little easier, the dusty baseboards of the mind feel cleaner.
So these are the effects of the lowish doses I’ve been taking. Some day in a safer environment I’d love to do a real full dose. But even at this “low” dose, it’s by far the most powerful drug I’ve ever taken, in a positive way.
homeonthemtn•1h ago
A single small dose of any given psychedelic can be enough to generate new mental benchmarks to process the world with (love, empathy, timelessness, selflessness, etc)
The drug itself is often irrelevant to the experience and it's impact, but we've unfortunately dragged along the ego of the underworld where each dose needs to be bigger and more exotic for bragging rights. In that light it's just another drug, and quite sad in my opinion.
DonHopkins•1h ago
The Great Smoke Off
https://www.youtube.com/watch?v=jCdCfJ3B4ok
woleium•1h ago
DonHopkins•1h ago
Downvoters: explain why that's a good idea, and if you do that too! And if you have any pro tips on mitigating your Ketamine Bladder and Heil Hitler Arm symptoms:
Urology & Continence Care Today: Ketamine bladders: what community nurses should know:
https://www.ucc-today.com/journals/issue/launch-edition/arti...
>KETAMINE AND THE URINARY TRACT: In recent years, the link between ketamine use and damage to the urinary tract has become apparent, with estimation that at least 26–30% of users experience at least one bladder symptom (Winstock et al, 2012; Misra, 2018). Using ketamine at least three times a week over a period of two years has been shown to result in altered bladder function, with some patients complaining of severe urological problems (Mak et al, 2011). This syndrome is often called ‘ketamine bladder’ or ‘ketamine cystitis’ in the literature (Jhang et al, 2015; Misra, 2018)
On the Campaign Trail, Elon Musk Juggled Drugs and Family Drama: As Mr. Musk entered President Trump’s orbit, his private life grew increasingly tumultuous and his drug use was more intense than previously known.
https://www.nytimes.com/2025/05/30/us/elon-musk-drugs-childr...
>Mr. Musk’s drug consumption went well beyond occasional use. He told people he was taking so much ketamine, a powerful anesthetic, that it was affecting his bladder, a known effect of chronic use. He took Ecstasy and psychedelic mushrooms. And he traveled with a daily medication box that held about 20 pills, including ones with the markings of the stimulant Adderall, according to a photo of the box and people who have seen it.
Edit: I'd say it's the ketamine abuser who's throwing Nazi salutes and pissing his pants who's the one perpetrating polarizing politics. I'm just using him as an example of why it's idiotic to abuse ketamine, which is quite on-topic. I'm not going to walk on egg shells to avoid triggering thin skinned MAGA "fuck your feelings" snowflakes.
tmn•1h ago
ux266478•39m ago
Elon Musk is a clown, but nobody on a dose of ketamine is doing anything, least of all making coherent gestures and political grandstands. Drug naive people should avoid having any degree of commentary on them, you always say the most ridiculous things.
Glamklo•12m ago
I think Musk alone is just a really depressing ahole who has no longer any social feedback due to his position.
ux266478•41m ago
Psychs are just drugs like any other. I think people get too wrapped up in the mysticism of them, or think the debilitating effects of heroic dosing is unique to them. How many uncs in the chat can't smoke weed anymore because it makes them have an awful time emotionally? How do you think dabbing a gram of wax would work out?
zingababba•4m ago
PaulHoule•1h ago
https://thefilmstage.com/john-lilly-and-the-earth-coincidenc...
but we had a visitor at home and enough to deal with. I read Lilly's books like
https://en.wikipedia.org/wiki/The_Center_of_the_Cyclone
and they were a bit of a hoot as he nearly killed himself multiple times injecting LSD and then testified that LSD was perfectly safe. I've known a few people, all male, who took LSD and developed a sort of "messiah complex" where they felt not a general spiritual "sacrament" experience but rather the opposite and some kind of hypertrophy of narcissism like the 'False Self' that Kohut warns about.
The article mentions 2-C-T-2 which I got in Europe which I understand was the closest people got to a commercially viable psychedelic in that it has a nice stimulant effect (easy walk from the German border to Děčín) and very nice visuals but seems to have little cosmic element so you are sitting on the toilet and feeling like a constipated sinner and that's about it.
Myself I don't have a lot of interest in LSD and company these days because for a while every time I take it it makes me aware of how I have many more nerve endings in my gut than I have on my skin so I feel turned inside out which isn't quite a "bad trip" but isn't very good either. Best thing that happened the last time was I laid down in the leaf litter and watched a pair of snakes having sex but I later picked four ticks off myself.
homeonthemtn•1h ago
I needed this phrase 20 years ago. Very well put.
fnord77•57m ago
The drug itself might actually be relevant. I suspect far more people per 100k have had negative reactions to say DMT than mushrooms, due to speed of onset, other receptors hit, etc.
trallnag•5m ago