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A Nicotine Analogue I Had Known and Didn't Love: 6-Methylnicotine

https://psychotechnology.substack.com/p/a-nicotine-analogue-i-had-known-and
17•eatitraw•3d ago

Comments

DaveZale•3d ago
Have you tried galantamine? It's abig hit for the "lucid dreaming" crowd. Sometimes also sold formulated with theanine (brand name lucidamine) and OTC
eatitraw•3d ago
I heard about it but I haven't tried.

What's your experience with it like?

DaveZale•3d ago
Galantamine has similar effects to nictonine without the nervousness, and lasts hours longer. It is nootropic, cognition enhancing with few side effects. It's a natural product, so here in the US, it falls into the dietary supplement category. Sharpened memory and attention span, and enhanced dreaming for many.
echelon_musk•1h ago
Without reading the TFA the title seems like a nice reference to TiHKAL and PiHKAL.
miningape•1h ago
The author's name is Sasha Putilin - might be the author's real name, but it's a lucky coincidence in that case
echelon_musk•14m ago
Later in the article he embeds a tweet that references Shulgin so the title at least is definitely intentional.
caliweed•27m ago
Substack uses the email as the placeholder, it prefills the subscribe input.

And it can't even be erased with backspace.

Basically if you're streaming or having any kind of observation they're gonna see your email.

proxysna•18m ago
Subscription form looks like a cigarette with a white field for an email and orange submit button. Nice touch/conicidence.
joemazerino•10m ago
Glad I'm reading this while on a nicotine break...

We're Losing Our Voice to LLMs

https://tonyalicea.dev/blog/were-losing-our-voice-to-llms/
106•TonyAlicea10•1h ago•90 comments

Arthur Conan Doyle explored men’s mental health through Sherlock Holmes

https://scienceclock.com/arthur-conan-doyle-delved-into-mens-mental-health-through-his-sherlock-h...
141•PikelEmi•5h ago•168 comments

Show HN: Runprompt – run .prompt files from the command line

https://github.com/chr15m/runprompt
34•chr15m•2h ago•9 comments

Linux Kernel Explorer

https://reverser.dev/linux-kernel-explorer
389•tanelpoder•10h ago•58 comments

Penpot: The Open-Source Figma

https://github.com/penpot/penpot
536•selvan•14h ago•125 comments

Show HN: MkSlides – Markdown to slides with a similar workflow to MkDocs

https://github.com/MartenBE/mkslides
23•MartenBE•3h ago•5 comments

Ray Marching Soft Shadows in 2D (2020)

https://www.rykap.com/2020/09/23/distance-fields/
138•memalign•9h ago•22 comments

Interactive λ-Reduction

https://deltanets.org/
84•jy14898•2d ago•20 comments

Mixpanel Security Breach

https://mixpanel.com/blog/sms-security-incident/
132•jaredwiener•9h ago•86 comments

DIY NAS: 2026 Edition

https://blog.briancmoses.com/2025/11/diy-nas-2026-edition.html
303•sashk•13h ago•168 comments

Technical Deflation

https://benanderson.work/blog/technical-deflation/
43•0x79de•3d ago•31 comments

Music eases surgery and speeds recovery, study finds

https://www.bbc.com/news/articles/c231dv9zpz3o
144•1659447091•11h ago•65 comments

G0-G3 corners, visualised: learn what "Apple corners" are

https://www.printables.com/model/1490911-g0-g3-corners-visualised-learn-what-apple-corners
92•dgroshev•3d ago•49 comments

Willis Whitfield: Creator of clean room technology still in use today (2024)

https://www.sandia.gov/labnews/2024/04/04/willis-whitfield-a-simple-man-with-a-simple-solution-th...
126•rbanffy•2d ago•49 comments

'Turncoat' by Dennis Sewell Review

https://www.historytoday.com/archive/review/turncoat-dennis-sewell-review
4•prismatic•4d ago•0 comments

The Concrete Pontoons of Bristol

https://thecretefleet.com/blog/f/the-concrete-pontoons-of-bristol
18•surprisetalk•6d ago•1 comments

Gemini CLI Tips and Tricks for Agentic Coding

https://github.com/addyosmani/gemini-cli-tips
348•ayoisaiah•22h ago•120 comments

The State of GPL Propagation to AI Models

https://shujisado.org/2025/11/27/gpl-propagates-to-ai-models-trained-on-gpl-code/
100•jonymo•3h ago•121 comments

S&box is now an open source game engine

https://sbox.game/news/update-25-11-26
376•MaximilianEmel•20h ago•130 comments

Show HN: SyncKit – Offline-first sync engine (Rust/WASM and TypeScript)

https://github.com/Dancode-188/synckit
8•danbitengo•2h ago•2 comments

Running Unsupported iOS on Deprecated Devices

https://nyansatan.github.io/run-unsupported-ios/
190•OuterVale•17h ago•84 comments

Last Issue of "ECMAScript News"

https://ecmascript.news/archive/es-next-news-2025-11-26.html
53•Klaster_1•10h ago•13 comments

Coq: The World's Best Macro Assembler? (2013) [pdf]

https://nickbenton.name/coqasm.pdf
110•addaon•12h ago•38 comments

Closest Harmonic Number to an Integer

https://www.johndcook.com/blog/2025/11/19/closest-harmonic-number-to-an-integer/
26•ibobev•6d ago•7 comments

Functional Data Structures and Algorithms: a Proof Assistant Approach

https://fdsa-book.net/
93•SchwKatze•14h ago•13 comments

Voyager 1 is about to reach one light-day from Earth

https://scienceclock.com/voyager-1-is-about-to-reach-one-light-day-from-earth/
1005•ashishgupta2209•1d ago•346 comments

A Fast 64-Bit Date Algorithm (30–40% faster by counting dates backwards)

https://www.benjoffe.com/fast-date-64
363•benjoffe•4d ago•86 comments

Migrating the main Zig repository from GitHub to Codeberg

https://ziglang.org/news/migrating-from-github-to-codeberg/
799•todsacerdoti•14h ago•695 comments

Fara-7B: An efficient agentic model for computer use

https://github.com/microsoft/fara
160•maxloh•21h ago•69 comments

Show HN: Era – Open-source local sandbox for AI agents

https://github.com/BinSquare/ERA
46•gregTurri•11h ago•11 comments