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Beginning January 2026, all ACM publications will be made open access

https://dl.acm.org/openaccess
717•Kerrick•3h ago•76 comments

GPT-5.2-Codex

https://openai.com/index/introducing-gpt-5-2-codex/
97•meetpateltech•58m ago•71 comments

Agent Skills is now an open standard

https://claude.com/blog/organization-skills-and-directory
113•adocomplete•2h ago•77 comments

Classical statues were not painted horribly

https://worksinprogress.co/issue/were-classical-statues-painted-horribly/
403•bensouthwood•6h ago•200 comments

Top Banned Books: The Most Banned Books in U.S. Schools – Pen America

https://pen.org/top-52-banned-books-since-2021/
5•FigurativeVoid•10m ago•0 comments

Military Standard on Software Control Levels

https://entropicthoughts.com/mil-std-882e-software-control
33•ibobev•2h ago•10 comments

Your job is to deliver code you have proven to work

https://simonwillison.net/2025/Dec/18/code-proven-to-work/
402•simonw•4h ago•328 comments

Launch HN: Pulse (YC S24) – Production-grade unstructured document extraction

29•sidmanchkanti21•3h ago•29 comments

Virtualizing Nvidia HGX B200 GPUs with Open Source

https://www.ubicloud.com/blog/virtualizing-nvidia-hgx-b200-gpus-with-open-source
83•ben_s•5h ago•21 comments

Are Apple gift cards safe to redeem?

https://daringfireball.net/linked/2025/12/17/are-apple-gift-cards-safe-to-redeem
389•tosh•4h ago•306 comments

Jonathan Blow has spent the past decade designing 1,400 puzzles

https://arstechnica.com/gaming/2025/12/jonathan-blow-has-spent-the-past-decade-designing-1400-puz...
274•furcyd•6d ago•371 comments

Dogalog: A realtime Prolog-based livecoding music environment

https://github.com/danja/dogalog
44•triska•4d ago•11 comments

Please Just Try Htmx

http://pleasejusttryhtmx.com/
278•iNic•4h ago•253 comments

RCE via ND6 Router Advertisements in FreeBSD

https://www.freebsd.org/security/advisories/FreeBSD-SA-25:12.rtsold.asc
117•weeha•11h ago•63 comments

Apples, Trees, and Quasimodes

https://systemstack.dev/2025/09/humane-computing/
12•entaloneralie•3d ago•1 comments

Creating apps like Signal could be 'hostile activity' claims UK watchdog

https://www.techradar.com/vpn/vpn-privacy-security/creating-apps-like-signal-or-whatsapp-could-be...
370•donohoe•7h ago•229 comments

Slowness is a virtue

https://blog.jakobschwichtenberg.com/p/slowness-is-a-virtue
207•jakobgreenfeld•8h ago•71 comments

Hightouch (YC S19) Is Hiring

https://hightouch.com/careers
1•joshwget•7h ago

I got hacked: My Hetzner server started mining Monero

https://blog.jakesaunders.dev/my-server-started-mining-monero-this-morning/
557•jakelsaunders94•21h ago•339 comments

Show HN: Paper2Any – Open tool to generate editable PPTs from research papers

https://github.com/OpenDCAI/DataFlow-Agent
6•Mey0320•2h ago•0 comments

Egyptian Hieroglyphs: Lesson 1

https://www.egyptianhieroglyphs.net/egyptian-hieroglyphs/lesson-1/
134•jameslk•13h ago•54 comments

Statistical Learning Theory and ChatGPT

https://kamalikachaudhuri.substack.com/p/statistical-learning-theory-and-chat
4•jxmorris12•2d ago•0 comments

Firefox will have an option to disable all AI features

https://mastodon.social/@firefoxwebdevs/115740500373677782
50•twapi•54m ago•43 comments

From profiling to kernel patch: the journey to an eBPF performance fix

https://rovarma.com/articles/from-profiling-to-kernel-patch-the-journey-to-an-ebpf-performance-fix/
35•todsacerdoti•4d ago•1 comments

Microscopic robots that sense, think, act, and compute

https://www.science.org/doi/10.1126/scirobotics.adu8009
26•XzetaU8•4d ago•2 comments

What is an elliptic curve? (2019)

https://www.johndcook.com/blog/2019/02/21/what-is-an-elliptic-curve/
126•tzury•12h ago•13 comments

Using TypeScript to Obtain One of the Rarest License Plates

https://www.jack.bio/blog/licenseplate
109•lafond•4h ago•100 comments

After ruining a treasured water resource, Iran is drying up

https://e360.yale.edu/features/iran-water-drought-dams-qanats
302•YaleE360•8h ago•247 comments

Heart and Kidney Diseases and Type 2 Diabetes May Be One Ailment

https://www.scientificamerican.com/article/heart-and-kidney-diseases-plus-type-2-diabetes-may-be-...
48•Brajeshwar•3h ago•25 comments

AI helps ship faster but it produces 1.7× more bugs

https://www.coderabbit.ai/blog/state-of-ai-vs-human-code-generation-report
164•birdculture•6h ago•140 comments
Open in hackernews

Heart and Kidney Diseases and Type 2 Diabetes May Be One Ailment

https://www.scientificamerican.com/article/heart-and-kidney-diseases-plus-type-2-diabetes-may-be-one-illness-treatable/
48•Brajeshwar•3h ago

Comments

SilverElfin•3h ago
> The ties are so strong that in 2023 the American Heart Association grouped the conditions under one name: cardio-kidney-metabolic syndrome (CKM), with “metabolic syndrome” referring to diabetes and obesity.

Seems like this is mostly an extension of the previously existing label of metabolic syndrome, now including kidney. Ozempic is mentioned and I take that to mean obesity is the cause. But are some of these ailments like diabetes reversible?

liveoneggs•2h ago
I think it's saying that diabetes (T2 is reliably reversible) causes damage to the heart and kidney but sometimes the connection isn't made and they treat the kidney/heart symptoms without addressing the cause (T2D).
qart•2h ago
> Amy Bies was recovering in the hospital from injuries inflicted during a car accident in May 2007

When an article starts like this, I instantly close it and wait for proper sources. Anyway, the phrase "metabolic syndrome" has been gaining currency for the last few years. For those who don't want to read journal papers and meta-analyses, there are plenty of doctors and fitness coaches (on YouTube) who have made videos on how to get metabolic syndrome under control or even reverse it. And many of the doctors do a good job of filtering and summarizing the research.

jeffbee•2h ago
> When an article starts like this, I instantly close it

Why? You don't believe in car crashes or what?

gnatman•2h ago
I think they probably mean “article that’s meant to share research but mostly shares anecdotes”. It’s a common framing for this kind of thing though, so they probably have to close a lot of articles after the first sentence.
qart•2h ago
A friend of mine told me a few days ago that he thinks LLMs are already smarter than most humans. I agreed with him instantly.
nh23423fefe•2h ago
Someone who wants to tell you something true doesn't lead their communication with emotional distraction. Kinda like how someone who is asking a real question doesn't disguise the question as an insult.
jeffbee•2h ago
It's not emotional distraction, it establishes the reason the subject was getting blood tests, which is revealed later in the same sentence. If this is your level of reading stamina you must find yourself very poorly informed. Even a tweet would be too long for you.
qart•1h ago
You will not build reading stamina or make yourself well informed with sappy stories. Learn some basic statistics and try reading research papers directly. "I have read more words" is a measure of only that, and nothing else. Maybe also a measure of the ability to not be able to separate wheat from chaff.
nh23423fefe•1h ago
tldr
ajkjk•28m ago
it's just fucking annoying, really. just a really irritating, baity way to write
derektank•1h ago
>Someone who wants to tell you something true doesn't lead their communication with emotional distraction.

This seems needlessly cynical. Someone can have multiple objectives in writing, to tell you facts and also to capture your attention or to convey an emotion and motivate you to action. Very little writing is done with a single purpose in mind. We don’t expect academics drafting research papers to eschew concerns about the impact the writing will have on their career for example.

Starting a story with an anecdote that humanizes the information is simply acknowledging the reality that people want more than just facts. If the latter was all they wanted, most of us would only read encyclopedias and textbooks.

autoexec•53m ago
In this case it really was just pointless distracting filler. The article would have been better without it. I reach for different books when I want drama or entertainment than when I want data and research. This article promises one thing and then clumsily shoves something else in randomly throughout. It really is obnoxious.
pas•1h ago
It's extremely lazy "writing".

Seems absolutely unnecessary, forced, immeasurably trite, off-puttingly boring, overused, so brazenly cliché that there has to be some kind of counter-intuitive selection going on, like with the email scammers that target those who are not immediately noticing the fraudulent intent.

... or simply our arrogance is showing, after all average minds discuss people, right?

jeffbee•1h ago
How many major national magazines have published your superior articles?
taproottap•4m ago
How many major national magazines publish good articles? The inverted pyramid is from newspapers and bears resemblance to scientific publishing while magazines bear more resemblance to the human interest crap between events when presenting the Olympics. Perfectly fine I suppose but then it's nice if they don't get confused about appropriate subjects.
barfoure•2h ago
You’ve got more patience than me. I read the title and decided I won’t bother reading the rest.
jeffbee•1h ago
And then bragged about this.
pas•1h ago
Still more value than the headline/article!
epcoa•41m ago
The term Metabolic Syndrome X has been around for more than a few years, unless nearly 40 is few (and I absolutely relate to that sentiment), just saying that concept was revved up in the 90s and of course has been an academic discussion going back to the early 20th century.

https://www.ahajournals.org/doi/10.1161/01.atv.0000111245.75...

https://pubmed.ncbi.nlm.nih.gov/3056758/

shevy-java•2h ago
It is all interconnected, but I am unsure about the claim made. The reason is simple: there can be numerous disease types. Person A may have different genetics than Person B, as one example, so responses of a body may be different for that reason alone; then there is lifestyle choice, health, age and so forth. So I don't agree with the claim in the title here that all is one ailment - that makes no sense to me.
bluGill•1h ago
We are reasonably confident that diabetes causes heart and kidney disease. However the converse - if I have heart disease (or kidney) I also have diabetes is not true: there are many possible causes of heart or kidney disease.

This logic error is easy to make, and the headlines all too often imply it, but it isn't always true (sometimes it is).

itchyouch•44m ago
I generally agree. It's all interconnected, and we could point to a singular cause, but to treat them all as one and of the same class of disease seems reductive and not useful.

Though, to be play devil's advocate for a second, it does seem that diabetes is typically where the symptoms start, and we do understand that diabetes is fundamentally metabolic and/or functional dysfunction in 1 or more of 7-ish different areas.

I think it's the level of perspective zoom + timing we take that makes the article's assertion either useful or not.

If we zoom out, while catching disease early on, and we address the metabolic conditions via lifestyle and/or certain drugs like GLP1, then we prevent the need to intervene on the kidney and cardiac front.

But if we zoom in to a specific issue, after disease has progressed a profound amount, a GLP1 intervention may be too little, too late.

Hopefully though, this may help the messaging to folks that if they are contending with metabolic disease that presents as diabetes, introducing lifestyle and pharma interventions early may be helpful on the larger epidemiological front.

brandonb•30m ago
HbA1c, or just diabetes as a binary variable, has been one of the main inputs into predicting heart attack risk for a long time.

The main marker of kidney function, eGFR, was added with the AHA/ACC's PREVENT equations in 2023.

I wrote a bit about the science behind heart risk calculators, and their various inputs like cholesterol, blood pressure, A1c, eGFR, and so on here: https://www.empirical.health/blog/heart-attack-risk-calculat...

matthewaveryusa•27m ago
>These three disorders could really be “CKM syndrome,” which can be treated with drugs like Ozempic

The article is trying so hard not to say that obesity is the cause. I call it the obesity pipeline: You start off young and obese and you don't have diabetes and it's all fine. Stay obese long enough and you get diabetes -> metformin. Stay in a diabetic state long enough and you get heart disease -> statins. These are obesity comorbidities.