WSIStreamer is relevant for storage systems without a filesystem. In this case, OpenSlide cannot work (it needs to seek and open the file).
Interesting guide to the Whole Slide Images (WSI) format. The surprising thing for me is that compression is used, and they note does not affect use in diagnostics.
Back in the day we used TIFF for a similar application (X-ray detector images).
matthberg•1h ago
0: https://protomaps.com/
el_pa_b•1h ago
As for digital pathology, the field is very much tied to scanner-vendor proprietary formats (SVS, NDPI, MRXS, etc).