You’re not having someone else take it for you?
I just take 5g/day with my morning coffee/water.
This is probably an important difference from the average participant of those studies.
Even once is rare unless I've been out drinking for the night.
Most of the computation and learning that occurs is attributable to the relative timing of spiking events. A lot of information can be encoded in the delay between 2 spikes. The advantage of biology is that there is no explicit quantization of the time domain that must occur. Biology gets to do a lot of things "for free". Simulating causality in a computer in a similar way requires a priority queue and runs like ass by comparison.
"Artificial neuron" was a useful metaphor at the beginning, but they really are a very simplified model based on what some people understood of neurology back then. They are not that useful to get insights into how actual neurons work.
Reading this article I'm a little confused by the author's conflation of brain energy and the energy expenditure of the body as a whole. In the beginning they mention:
> "Your brain consumes roughly 20 to 25% of your body's total energy at rest"
while later they say:
> "Even chess grandmasters, who sit for hours in states of intense concentration, burn only about 1.67 calories per minute while playing, compared to 1.53 calories per minute at rest"
That second figure seems to refer to whole-body expenditure, not just the brain. And intense cognitive work doesn't happen in a metabolic vacuum - there's increased cerebral blood flow, elevated sympathetic nervous system activity, changes in heart rate variability, hormonal shifts (cortisol, adrenaline). These all have systemic metabolic costs that go beyond the glucose the neurons themselves consume. So the "it's just a banana and a half" framing might be undercounting by quietly switching between brain-only and whole-body measurements.
Also somewhat related - the link to businessinsider about chess grandmasters is broken, but another very interesting rabbit hole here is how energy expenditure is actually measured. A lot of what consumer devices and even many studies report is based on proxy biomarkers like heart rate, HRV, weight, age, and sex, run through linear regression models. True calorimetry (indirect via gas exchange, or direct in a metabolic chamber) is expensive and impractical outside lab settings. That means the precise calorie figures cited with such confidence - the "100 to 200 extra calories" from a day of thinking, or the per-minute burn rates of chess grandmasters - likely carry wider error bars than the article suggests. We don't really have a great way to measure real-world energy expenditure accurately at the individual level, which makes me a bit cautious about the neat narrative of "thinking is calorically cheap, full stop."
That said, the core point about adenosine accumulation and perceived exertion affecting training quality is fascinating and well-supported — that part of the article is genuinely useful regardless of the calorie accounting.
The big copy on the front page says:
> Your Apple Watch *tracks* VO2 Max—one...
While you have to read through FAQ where you see:
> The watch *estimates* your cardio fitness during outdoor activities and stores it in Apple Health, which our app reads automatically.
All emphasis are mine.
I think it's a little disingenuous to sell this as "Your VO2 Max, finally visible" when it's actually just an estimate from a watch, based on biomarkers. When the real VO2 is measured in a lab with a more involved equipment.
A 2025 validation study involving 30 participants found that Apple Watch underestimated VO2 max by a mean of 6.07 mL/kg/min (95% CI 3.77–8.38) when compared to indirect calorimetry, the gold standard method. The mean absolute percentage error (MAPE) was 13.31%, and the limits of agreement showed considerable variability ranging from -6.11 to 18.26 mL/kg/min [1]. Another 2024 study found similar results, with the Apple Watch Series 7 showing a MAPE of 15.79% and poor reliability (ICC = 0.47) [2].
[1]: https://journals.plos.org/plosone/article?id=10.1371%2Fjourn...
soared•1h ago
samplatt•1h ago
instagib•1h ago
They list a study and more info on that page. Probably why almost all pre-workouts include caffeine. Some push for 300mg per serving.
Yohimbe gives some weird heart effects also.