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Big Breakfast Alters Appetite, Gut Health

https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/big-breakfast-diet-composition-impacts-on-appetite-control-and-gut-health-a-randomized-weight-loss-trial-in-adults-with-overweight-or-obesity/69D4E150EAE7D9632D33904D7A4AE5FA
42•wjb3•2h ago

Comments

hristov•1h ago
Interesting but they had no control.
baxtr•1h ago
The whole study design seems odd.

Why not add a third high-fiber + high-protein group for example?

VLM•1h ago
They would have needed 20 participants, which is too many.

Soon we will have more participants in the HN comments for the study, than were studied in the study.

Aeglaecia•49m ago
im thinking you would need a group to skip breakfast too ...
AnEro•1h ago
I feel like the regular weight loss group was? Since it isn't necessarily rocket science for having mostly men stay in an easily determinable caloric deficit to lose weight. (Women have usually would be harder due to more conditions and hormone interactions that make finding a TDEE not as simple.)
Apocryphon•1h ago
They didn't eat that much.
benmaraschino•1h ago
They used a crossover design, so each subject served as their own control. Not a bad choice for trials like this as you gain a lot of statistical power with fewer participants than a parallel-arm, non-crossover design.
hristov•6m ago
I don't think they used crossover design. There is no evidence in the abstract that they used crossover design.

If they used crossover design they should have all participants go through a second trial period where they consume the same diet but with light breakfast and more caloric lunch and dinner. Then they could actually have more insight on the main thesis of their study, i.e. whether bug breakfast alters appetite.

chairhairair•1h ago
19 participants.
Oras•1h ago
>> therefore 19 participants completed the study (2 females and 17 males) and their data are presented throughout

Who in their own mind decided that this is a "study" worth publishing?

AnEro•1h ago
Someone with quotas
godelski•52m ago
You're reading the study wrong.

You read

  We saw this effect, so it's real. 
In actuality it is

  We saw this effect in a small study, so it's worth doing a larger study.
It's worth publishing because it's evidence and motivation to do further studying. And if you're asking "Why not start large?" the answer is obvious: money.
steve_adams_86•30m ago
Especially in dietary studies. You either spend a lot on high quality, controlled studies where you can nail down parameters (takes a LOT of labour), or you spend on facilitating much larger studies where you make up for precision and control with volume.

There are trade offs in either case and some types of research where one is more suitable than the other. But the best case is a combination of the two, and it's exceedingly rare.

Maybe there are other options but this seems to be the polar nature of these studies from what I've seen.

kibibu•49m ago
The paper includes a section on power analysis which justifies the sample size (although the justification is for a sample of 20, they recruited 25 eligible participants and lost 6 in screening).

Some points though:

- A within-participants study has inherently more power than a between-subjects study. Trying two different diets with the same person removes a lot of variables that you'd need to control for in between-subjects studies (and yes, they randomized the order of intervention and found no difference based on order)

- It looks like this was conducted in a way that supported compliance with the protocol, and using analysis techniques that would be unwieldy for a much larger sample size.

Even with N=19, the reported significance is very compelling.

yokoprime•1h ago
Average age was 57, which may be rather high. Also: why not test out combining both diets?
mijoharas•1h ago
That was the point I stopped reading.
GeoAtreides•11m ago
go on, explain why you think there is a problem with the sample size. But no words, only clear statistical calculus. I'll wait.
abainbridge•1h ago
The abstract begins, "Growing evidence supports early eating to control appetite and energy balance". What does that mean? My unskilled reading of it is that there is recent evidence that eating breakfast helps with weight loss. But I'm confused because there was a 2019 meta-analysis that found that eating breakfast does NOT help with weight loss. https://www.bmj.com/content/364/bmj.l42
tonyedgecombe•1h ago
The problem there might be what people are eating for breakfast.
DANmode•13m ago
Right.

How many of these studies used buttered eggs and potato as the sole breakfast?

dfex•1h ago
It sounds like this study might have been funded by.... Big Breakfast.

I'll see myself out.

nobody083648•1h ago
Dammit I came here to make this joke
mike_d•45m ago
TLDR: A weight loss diet centered around a big breakfast yields weight loss results. That breakfast loaded with protein made you feel fuller and suppressed your appetite (which helps you follow a diet), where a fiber loaded diet produced more beneficial gut bacteria.

The study has a pretty small sample size, but it seems well designed and matches what you'd expect.

puppycodes•36m ago
study says we should do a real study
jeffbee•23m ago
"big meal alters appetite" is a hell of a conclusion. Definitely going to need to study that one.
DANmode•12m ago
Appetite is intertwining endocrine functions that contain way more moving datapoints than just stomach empty vs stomach full.
ethanpil•22m ago
Asked Grok to ELI5 the abstract:

*Okay, kiddo, imagine this like a fun science experiment about breakfast!*

Scientists wanted to know: *"Does what you eat for breakfast matter a LOT when you're trying to lose weight?"*

They got 19 grown-ups who were carrying extra weight. Each person tried *TWO different "big-breakfast" diets* for 28 days each (like a month). - Both diets made people eat *most of their food early* (45% at breakfast, then less and less during the day). - The only big difference? The *breakfast itself*!

*Diet 1: High-Fiber Breakfast* (think lots of fruits, veggies, oats, beans — the "rough, chewy" stuff) *Diet 2: High-Protein Breakfast* (think eggs, yogurt, chicken, beans — the "filling, muscle stuff")

### What happened?

1. *Weight loss* - High-fiber breakfast diet → people lost *more weight* (about 11 pounds / 4.87 kg) - High-protein breakfast diet → people lost *a bit less* (about 8.5 pounds / 3.87 kg) → So the fiber one won for dropping pounds!

2. *Feeling hungry* - High-protein breakfast was the *winner* here. People said they felt *fuller and less hungry* all day.

3. *Tiny bugs in your tummy (gut bacteria)* - High-fiber breakfast made the *good bugs* super happy and grow way more! (Special helpful ones like "Bifido", "Faecalibacterium" and "Roseburia" — they make a healthy tummy juice called butyrate.)

### Super simple takeaway (the ELI5 version):

- Eating a *big breakfast* helps you lose weight (way better than skipping it or eating late). - If you want to *lose the most weight* and keep your tummy bugs healthy → load up on *fiber* at breakfast. - If you want to *feel the least hungry* → load up on *protein* at breakfast.

Both are good! The scientists basically proved: *Breakfast is the boss of your day.* Make it big, and whether you pick the "chewy veggie" version or the "eggy" version changes what wins — more weight gone, less hunger, or happier belly bugs.

Pretty cool, right? Breakfast isn't just food... it's like a remote control for your body!

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