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Gemma 4 on iPhone

https://apps.apple.com/nl/app/google-ai-edge-gallery/id6749645337
257•janandonly•3h ago•71 comments

LÖVE: 2D Game Framework for Lua

https://github.com/love2d/love
123•cl3misch•1d ago•40 comments

Artemis II crew see first glimpse of far side of Moon [video]

https://www.bbc.com/news/videos/ce3d5gkd2geo
357•mooreds•8h ago•279 comments

Eight years of wanting, three months of building with AI

https://lalitm.com/post/building-syntaqlite-ai/
518•brilee•9h ago•161 comments

Running Gemma 4 locally with LM Studio's new headless CLI and Claude Code

https://ai.georgeliu.com/p/running-google-gemma-4-locally-with
118•vbtechguy•5h ago•30 comments

Caveman: Why use many token when few token do trick

https://github.com/JuliusBrussee/caveman
636•tosh•13h ago•298 comments

Music for Programming

https://musicforprogramming.net
47•merusame•4h ago•13 comments

A tail-call interpreter in (nightly) Rust

https://www.mattkeeter.com/blog/2026-04-05-tailcall/
108•g0xA52A2A•7h ago•13 comments

Computational Physics (2nd Edition)

https://websites.umich.edu/~mejn/cp2/
76•teleforce•6h ago•10 comments

Nanocode: The best Claude Code that $200 can buy in pure JAX on TPUs

https://github.com/salmanmohammadi/nanocode/discussions/1
125•desideratum•8h ago•22 comments

UK intelligence censored report on global warming and homeland security

https://theoryofchange1.substack.com/p/from-global-warming-to-homeland-security
48•ewidar•1h ago•24 comments

The underrated benefits of always having oatmeal at lunch

https://hazn.com/oatmeal
29•surprisetalk•3d ago•35 comments

The Mechanics of Steins Gate (2023) [pdf]

https://github.com/Votuko/steins-gate-mechanics/blob/main/The%20Mechanics%20of%20Steins%20Gate%20...
4•Ariarule•46m ago•0 comments

The Free Market Lie: Why Switzerland Has 25 Gbit Internet and America Doesn't

https://sschueller.github.io/posts/the-free-market-lie/
76•sschueller•3h ago•54 comments

LibreOffice – Let's put an end to the speculation

https://blog.documentfoundation.org/blog/2026/04/05/lets-put-an-end-to-the-speculation/
132•eisa01•4h ago•75 comments

From birds to brains: My path to the fusiform face area (2024)

https://www.kavliprize.org/nancy-kanwisher-autobiography
31•everbody•5h ago•0 comments

Lisette a little language inspired by Rust that compiles to Go

https://lisette.run/
244•jspdown•15h ago•128 comments

Finnish sauna heat exposure induces stronger immune cell than cytokine responses

https://www.tandfonline.com/doi/full/10.1080/23328940.2026.2645467#abstract
293•Growtika•9h ago•196 comments

Friendica – A Decentralized Social Network

https://friendi.ca/
112•janandonly•11h ago•43 comments

Show HN: Contrapunk – Real-time counterpoint harmony from guitar input

https://contrapunk.com/
108•waveywaves•21h ago•40 comments

Baby's Second Garbage Collector

https://www.matheusmoreira.com/articles/babys-second-garbage-collector
38•matheusmoreira•3d ago•11 comments

The threat is comfortable drift toward not understanding what you're doing

https://ergosphere.blog/posts/the-machines-are-fine/
771•zaikunzhang•12h ago•509 comments

Hightouch (YC S19) Is Hiring

https://hightouch.com/careers#open-positions
1•joshwget•10h ago

Perfmon – Consolidate your favorite CLI monitoring tools into a single TUI

https://github.com/sumant1122/Perfmon
39•paperplaneflyr•8h ago•6 comments

Tracing Goroutines in Realtime with eBPF

https://sazak.io/articles/tracing-goroutines-in-realtime-with-ebpf-2026-03-31
55•darccio•3d ago•6 comments

Musician says AI company is cloning her music, filing claims against her

https://twitter.com/i/status/2040577536136974444
29•lando2319•2h ago•2 comments

Bacteria found in the human intestine capable of improving muscle strength

https://www.ugr.es/en/about/news/bacteria-found-human-intestine-capable-improving-muscle-strength
101•gnabgib•3h ago•59 comments

Just 'English with Hanzi'

https://www.oldnorthwhale.com/p/why-modern-chinese-is-just-english
72•scour•2d ago•40 comments

Qwen-3.6-Plus is the first model to break 1T tokens processed in a day

https://twitter.com/openrouter/status/2040239467865489874
15•Alifatisk•1h ago•10 comments

Scientists Figured Out How Eels Reproduce (2022)

https://www.intelligentliving.co/scientists-finally-figured-out-how-eels-reproduce/
104•thunderbong•3d ago•22 comments
Open in hackernews

Bacteria found in the human intestine capable of improving muscle strength

https://www.ugr.es/en/about/news/bacteria-found-human-intestine-capable-improving-muscle-strength
101•gnabgib•3h ago

Comments

rendall•2h ago
...in mice. :/
Aboutplants•2h ago
Maybe we need to flip it and start testing new mouse drugs on Humans?
RobRivera•2h ago
We need deeper research into mouse bites as medicine.
wpm•2h ago
More mouse bites!
wellthisisgreat•2h ago
The mouse lobby rears its [tiny] head again
stefs•2h ago
As always. But it's a first step.
jb1991•2h ago
The reflex “in mice” meme has been annoying for quite some time.
adrian_b•2h ago
It is not that simple.

They have found first a correlation between the presence of this species of bacteria and muscle strength in humans.

Then they have made an attempt to determine whether this correlation reflects a causal relationship.

So they have fed mice previously treated with antibiotics, to remove their own gut bacteria, with this kind of bacteria extracted from humans.

They have indeed seen an increase in muscular strength at the mice that have received the human bacteria, which seems to confirm causality between the presence of this bacterium and muscle strength.

While they have also determined the biochemical changes in muscles that have caused increased strength, the mechanism of how the bacteria have influenced that remains a mystery. Perhaps this bacterium produces some substance that mimics a human hormone, e.g. a steroid.

Paywalled research article: https://gut.bmj.com/content/early/2026/03/03/gutjnl-2025-336...

rendall•1h ago
So, literally, "Bacteria found in the human intestine capable of improving muscle strength in mice" then.
SV_BubbleTime•1h ago
If we wanted to we could either make super mice. Or have a great head start on really unethical but impressive human health progress… that just comes from all the horrible human testing that would be necessary.
grg0•2h ago
This is why I tell my gym bros that they should quit all that Celsius garbage and stick to the basics. You should measure your gut health by the quality of your feces (consistency, texture, colour, shape), and then your muscles and rest of your body will thank you. This research is evidence of that. The science is still catching up.
stefs•2h ago
Celsius?
grg0•2h ago
Corrected, thank you.
acessoproibido•2h ago
What do you mean by celcius garbage?

Fun fact: in Germany most toilets have a built in 'inspection plate' so you can look at your shit before you flush it. In other places I often found it hard to judge the quality because you can't even see it well or it gets flushed instantly

grg0•2h ago
I meant Celsius, a popular energy drink in the US, but more generally that and the processed foods people take in for some supposed performance gains.
SV_BubbleTime•1h ago
It’s gross sugar water. I accidentally bought some once and years later I found out people are intentionally drinking it.
unsupp0rted•2h ago
I always wondered if the "inspection plate" was really for inspection or some side-effect of plumbing or something
p1anecrazy•2h ago
One explanation I heard is “helps save water when flushing”
b65e8bee43c2ed0•2h ago
I assume they existed to prevent backsplash.
soopypoos•2h ago
it also helps avoid Neptune's kiss
b112•2h ago
It's literally in the bowl you were just sitting in. I'm not sure where the inspection plate goes. Is this an AI saying this? Is the rest of the thread AIs? Is this all made up. What's happening!?

I thought learning about bidets was a new experience, now inspection plates?!

I thought I understood this part of my life.

scared and confused

kadoban•1h ago
It's just different shapes of toilets. There's a part without water directly under you, and then when you flush it's flooded.
rokkamokka•1h ago
Just do a quick search for German toilet and you'll see.
grg0•39m ago
There are no AIs here, only gains.
tvshtr•2h ago
"Bro, take a look at my poop"
notesinthefield•1h ago
It is so wonderful to hear someone else say this. My spouse and friends think In so weird for emphasizing optimizing your diet for things that digest well, macro dense and give you good shits. I am quietly pleased when my own looks completely normal and uninteresting.
RobRivera•2h ago
GAINS
youalmosthadit•1h ago
No grain no gain
toomuchtodo•2h ago
Roseburia inulinivorans probiotic when? Probably add it to the premade protein shakes and mix specific to those building muscle.

https://en.wikipedia.org/wiki/Roseburia_inulinivorans

Giorgi•2h ago
Well... assuming this article is just shilling, soon.
FurstFly•2h ago
My gym bros gonna be so shocked lol
shevy-java•2h ago
So Homer Simpson was right in the end.

Beer is basically fermented sugar (well, glucose converted to ethanol by yeast, for the most part; though its maltose first, yeast, bacteria etc... prefer glucose and maltose is a disaccharide of glucose: Maltose).

mikrl•2h ago
Pretty sure Duff was a heavily filtered macro beer.

Not saying engineered beer is necessarily bad- Sapporo and Asahi never disappoint- but I imagine you would want to stick to unfiltered and unpasteurized to retain some of the more… alive compounds.

joshuahaglund•2h ago
No beer has nothing to do with Roseburia genus bacteria
rramadass•2h ago
Perhaps there is also a direct correlation between this microbiome and longevity in the so-called "blue zones" of the world like Okinawa, Sardinia etc.

We are what we eat.

tvshtr•2h ago
Some of the blue zones were disproven, due to falsified documentation or lack of it.
patmorgan23•2h ago
IIRC there are several of the "Blue Zones" where just bad government records. (People who had incorrect birth dates, or had already died and the government just didn't know about it)
SV_BubbleTime•1h ago
Jose DeSanquin Demarco of Bolivia is now the world’s oldest man at 117, he attributes his health to 10 hours daily in the sun and fields farming quinoa.

Photographed here, Jose’s 90 year old wife holds their newborn twins.

jareklupinski•1h ago
> We are what we eat.

putting together a theory on how bacteria organized multicellular life to exploit our macro-movements and proliferate between damp spots

roschdal•2h ago
I need this
culi•2h ago
It works by converting fibers into butyrate. You should maintain a high fiber diet to promote Roseburia in your gut
adrian_b•2h ago
It is known that the bacteria that produce high amount of butyrate are beneficial, e.g. by decreasing the risk of colon cancer, but this does not seem sufficient to explain the increase in muscle strength that seems to be caused by this species alone.

The study has first found in humans a correlation between muscle strength and the presence of this bacterium. Then they have attempted to determine whether this correlation is due to a causal relationship by killing the gut bacteria in mice, then feeding them with this kind of human gut bacteria. The result was an increased muscle strength, which seems to confirm causality.

How the bacteria increase muscle strength remains unknown. I think that a possible explanation may be that this bacterium produces some substance that mimics a human hormone, e.g. a steroid, in which case it would be a kind of natural doping.

sandworm101•2h ago
Natural or otherwise, one must wonder if there are similar downsides.
adrian_b•2h ago
True.
DiscourseFan•2h ago
I've always eaten a ton of fiber, to the point where if I stop I get constipated, and I've always put on muscle fairly easily.
b65e8bee43c2ed0•1h ago
the fiber will promote all bacteria in your gut, not just this particular strain.
moffkalast•1h ago
You know it would be funny if at least once the finding would be "you should eat more hamburgers" or something.
ben8bit•2h ago
Eat some apples and add 10lb to your bench. Nice!
sublinear•2h ago
> This opens up the possibility that the bacterium under investigation could be used as a probiotic to help preserve muscle strength during aging

Maybe, but it's really hard to control for other variables here. They don't know what's causing this bacteria to diminish over time in older adults in the first place.

It could totally just be dietary habits getting worse over time as people let themselves go. Regardless of age, most people already don't eat enough protein and when they do they might not be getting "complete" proteins either (missing amino acids is common with plant-based foods).

fylo•2h ago
For me personally, as I've gotten older I have continued to eat better and more consistently than I ever did earlier in life. I think the long term study of your own life tends to show you that diet is one of, if not the, primary factor in short and long term health and well being.
ramoz•2h ago
Did quick research on how to support the bacteria growth

> Dietary modifications that emphasize high-fiber and prebiotic foods and dietary supplements may support the healthy growth of Roseburia [1]

> As stated above, a Mediterranean diet is associated with increased Roseburia growth. This diet emphasizes primarily plant-based foods: whole fruits and vegetables, whole grains, legumes, nuts and seeds, olive oil, and fatty fish. The high fiber and resistant starch content of these foods may fuel Roseburia and the other beneficial flora of the human microbiome [1]

> Polyphenols are plant compounds abundant in fruits, vegetables, tea, and coffee. Emerging research indicates that polyphenols can enhance Roseburia abundance indirectly by inhibiting harmful bacteria and fostering beneficial ones. [2]

[1] https://www.rupahealth.com/post/roseburia-spp-101

[2] https://www.innerbuddies.com/pages/gut-microbiome-101/gut-ba...

OfirMarom•2h ago
Thanks for the dietary info! Helps make it concrete.
underlipton•38m ago
tl;dr They don't know.

I wish scientists would be more open about how little they understand digestion and nutrition, particularly on an individual level. Advice gets presented as an if-then, when it's not.

soopypoos•1h ago
Neisseria gonorrhoeae doesn't even have muscles but it can pull 100,000x its own weight
emanuele-em•1h ago
Every few months there's a new study showing gut bacteria control yet another thing we thought was "us." Mood, cognition, immune response, and now muscle strength. Starting to wonder what's even left.
dd8601fn•1h ago
And yet, still no serious fixes for any of it that aren’t just jabronis pitching overpriced and ineffective supplements.
g-b-r•1h ago
Will people really go after Tom Brady's stuff now? xD
sharpshadow•1h ago
Active cultures are available[0] and there is certainly a way to make them available to the gut isn’t there?

0. https://webshop.dsmz.de/en/bacteria/Roseburia-inulinivorans....

blitzar•7m ago
Gym bros are going to be eating their own faeces for the gainz.