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Method to reverse cellular ageing is about to be tested in humans

https://www.nature.com/articles/d41586-026-01024-7
17•jawiggins•2h ago

Comments

flowerthoughts•18m ago
> The company will proceed slowly, says Sharon Rosenzweig-Lipson, chief scientific officer at the company, treating up to 12 people with a specific type of glaucoma, and then up to 6 people with another condition, called NAION, that causes acute optic nerve damage. The genes will be regulated by a genetic switch that turns them on only when participants take a certain antibiotic.

The End of Eleventy

https://brennan.day/the-end-of-eleventy/
131•ValentineC•5h ago•76 comments

Small models also found the vulnerabilities that Mythos found

https://aisle.com/blog/ai-cybersecurity-after-mythos-the-jagged-frontier
999•dominicq•14h ago•272 comments

US appeals court declares 158-year-old home distilling ban unconstitutional

https://www.theguardian.com/law/2026/apr/11/appeals-court-ruling-home-distilling-ban-unconstituti...
84•Jimmc414•2h ago•44 comments

Tofolli gates are all you need

https://www.johndcook.com/blog/2026/04/06/tofolli-gates/
18•ibobev•4d ago•0 comments

How We Broke Top AI Agent Benchmarks: And What Comes Next

https://rdi.berkeley.edu/blog/trustworthy-benchmarks-cont/
342•Anon84•11h ago•87 comments

How Complex is my Code?

https://philodev.one/posts/2026-04-code-complexity/
94•speckx•4d ago•18 comments

Dark Castle

https://darkcastle.co.uk/
171•evo_9•11h ago•22 comments

447 TB/cm² at zero retention energy – atomic-scale memory on fluorographane

https://zenodo.org/records/19513269
195•iliatoli•11h ago•99 comments

Why meaningful days look like nothing while you are living them

https://pilgrima.ge/p/the-grand-line
23•momentmaker•4h ago•10 comments

Simplest Hash Functions

https://purplesyringa.moe/blog/simplest-hash-functions/
25•ibobev•4d ago•18 comments

Pijul a FOSS distributed version control system

https://pijul.org/
125•kouosi•4d ago•22 comments

Apple Silicon and Virtual Machines: Beating the 2 VM Limit (2023)

https://khronokernel.com/macos/2023/08/08/AS-VM.html
185•krackers•10h ago•128 comments

How a dancer with ALS used brainwaves to perform live

https://www.electronicspecifier.com/products/sensors/how-a-dancer-with-als-used-brainwaves-to-per...
31•1659447091•5h ago•1 comments

Building a Z-Machine in the worst possible language – Whitebeard's Realm

https://whitebeard.blog/posts/building-a-z-machine-in-elm/
21•techbelly•4h ago•1 comments

Advanced Mac Substitute is an API-level reimplementation of 1980s-era Mac OS

https://www.v68k.org/advanced-mac-substitute/
231•zdw•15h ago•60 comments

Cirrus Labs to join OpenAI

https://cirruslabs.org/
256•seekdeep•18h ago•125 comments

Show HN: Pardonned.com – A searchable database of US Pardons

418•vidluther•1d ago•231 comments

Surelock: Deadlock-Free Mutexes for Rust

https://notes.brooklynzelenka.com/Blog/Surelock
201•codetheweb•3d ago•66 comments

How to build a `Git diff` driver

https://www.jvt.me/posts/2026/04/11/how-git-diff-driver/
105•zdw•13h ago•12 comments

Software Preservation Group: C++ History Collection

https://softwarepreservation.computerhistory.org/c_plus_plus/
18•quuxplusone•5h ago•2 comments

Who was "Not Even Wrong" first? [2023]

https://www.math.columbia.edu/~woit/wordpress/?p=13455
5•bookofjoe•4d ago•2 comments

The Soul of an Old Machine

https://skalski.dev/the-soul-of-an-old-machine/
48•mskalski•4d ago•10 comments

High-Level Rust: Getting 80% of the Benefits with 20% of the Pain

https://hamy.xyz/blog/2026-01_high-level-rust
19•maxloh•7h ago•8 comments

What is a property?

https://alperenkeles.com/posts/what-is-a-property/
68•alpaylan•4d ago•19 comments

Optimal Strategy for Connect 4

https://2swap.github.io/WeakC4/explanation/
284•marvinborner•3d ago•31 comments

Every plane you see in the sky – you can now follow it from the cockpit in 3D

https://flight-viz.com/cockpit.html?lat=40.64&lon=-73.78&alt=3000&hdg=220&spd=130&cs=DAL123
312•coolwulf•3d ago•58 comments

The APL programming language source code (2012)

https://computerhistory.org/blog/the-apl-programming-language-source-code/
65•tosh•13h ago•20 comments

Keeping a Postgres Queue Healthy

https://planetscale.com/blog/keeping-a-postgres-queue-healthy
93•tanelpoder•14h ago•25 comments

New synthesis of astronomical measurements shows Hubble tension is real

https://noirlab.edu/public/news/noirlab2611/?nocache=true&lang=en
57•anigbrowl•12h ago•13 comments

The Problem That Built an Industry

https://ajitem.com/blog/iron-core-part-1-the-problem-that-built-an-industry/
120•ShaggyHotDog•17h ago•44 comments