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Objective metrics that change the most as we age

https://www.empirical.health/blog/biomarkers-that-change-with-age/
11•brandonb•1h ago

Comments

cj•36m ago
Yet, the metrics in the article are routinely ignored (or not tracked at all) by your typical PCP doctor.

I think more frequent and more thorough blood testing is something I'd love to see become more common place. Even if it's for no other reason than to know what your benchmark is so that if you have a health issue down the line, you know what your values were when you weren't sick.

phasefactor•23m ago
The training kicks in and my knee-jerk reaction to not one of the graphs starting at zero is to discount the trustworthiness of the entire article, whether that is well deserved or not...
brandonb•39s ago
For most of these metrics, zero is not a logically possible data point. For example, somebody with an HbA1c of 0 would be dead.

I think Anthropic and OpenAI have found product-market fit

https://simonwillison.net/2026/May/27/product-market-fit/
130•simonw•1h ago•136 comments

SimCity 3k in 4k (2025)

https://www.thran.uk/writ/hdid/2025/12/simcity-3k-in-4k.html
71•speckx•56m ago•18 comments

DuckDuckGo search saw 28% more visits after Google said people love AI mode

https://www.pcgamer.com/hardware/duckduckgos-ai-free-search-saw-nearly-28-percent-more-visits-in-...
271•HelloUsername•2h ago•136 comments

Last.fm is now independent

https://support.last.fm/t/last-fm-is-now-independent/118591
338•twistslider•2h ago•103 comments

Gemini, Gophers, and Fingers. Oh My Alternative Internets Beyond HTTPS

https://brennan.day/gemini-gophers-and-fingers-oh-my-alternative-internets-beyond-https/
15•ChrisArchitect•1h ago•5 comments

Mini Micro Fantasy Computer

https://miniscript.org/MiniMicro/index.html#about
199•nicoloren•8h ago•72 comments

Training our own AI models

https://posthog.com/blog/training-ai-models
145•tartieret•2h ago•96 comments

Tech CEOs are apparently suffering from AI psychosis

https://techcrunch.com/2026/05/27/tech-ceos-are-apparently-suffering-from-ai-psychosis/
276•IAmGraydon•3h ago•127 comments

Reflex (YC W23) Is Hiring SWEs, Growth, and GTM Roles

https://www.ycombinator.com/companies/reflex/jobs
1•apetuskey•1h ago

Matrix Multiplications on GPUs Run Faster When Given "Predictable" Data (2024)

https://www.thonking.ai/p/strangely-matrix-multiplications
114•tosh•4d ago•32 comments

In-Browser Container Builds

https://ochagavia.nl/blog/fully-in-browser-container-builds/
11•wofo•2d ago•0 comments

Show HN: I made an emergency page for my family

https://help.delduca.org
45•delduca•4h ago•59 comments

A Comma and a Question Mark, Redux: Quick Terminal Helpers Using Pi

https://z3ugma.github.io/2026/05/25/a-comma-and-a-question-mark/
16•z3ugma•1d ago•3 comments

All of human cooking compressed into 2 megabytes

https://arxiv.org/abs/2605.22391
286•josefchen•10h ago•106 comments

Theseus: Translating Win32 to WASM

https://neugierig.org/software/blog/2026/05/theseus-wasm.html
44•ingve•2d ago•11 comments

Multi-Agent LLM System for Automated Vulnerability Discovery and Reproduction

https://arxiv.org/abs/2605.21779
3•root-parent•50m ago•0 comments

Canada to order military plane fleet from Sweden in shift from US suppliers

https://www.theguardian.com/world/2026/may/27/canada-sweden-saab-globaleye-aircraft
39•tosh•1h ago•3 comments

Incident with Pull Requests, Issues, Git Operations and API Requests

https://www.githubstatus.com/incidents/xy1tt3hs572m
208•maxnoe•6h ago•160 comments

My new obsession: A horse-racing board game of pure luck

https://alexanderbjoy.com/horse-race-board-game/
35•surprisetalk•2d ago•22 comments

XLIDE: VBA without excel

https://github.com/WilliamSmithEdward/xlide_vscode
52•sts153•6h ago•16 comments

Phloto for My Photo Flow

https://cceckman.com/writing/phloto/
28•evakhoury•21h ago•2 comments

Show HN: Open-source Workspace (mail,docs,spreadsheet,drive) web/iOS

https://tinycld.org/
28•nathanstitt•3h ago•13 comments

The Melancholy of Slaying Monsters

https://thereader.mitpress.mit.edu/the-strange-melancholy-of-slaying-monsters/
244•prismatic•23h ago•113 comments

Cloudflare Flagship

https://developers.cloudflare.com/flagship/
326•tjek•18h ago•165 comments

Valve raises Steam Deck prices by more than $200

https://www.theverge.com/games/938340/valve-steam-deck-price-increase
13•droidjj•34m ago•4 comments

I'm Tired of Talking to AI

https://orchidfiles.com/im-tired-of-ai-generated-answers/
1738•theorchid•7h ago•839 comments

Raft Consensus with a Minority of Nodes

https://padhye.org/raft-minority/
105•moarbugs•1d ago•16 comments

Atomically precise mechanosynthesis of carbon structures on hydrogenated Silicon

https://arxiv.org/abs/2605.27250
39•gene-h•7h ago•5 comments

Claude Code as a Daily Driver: Claude.md, Skills, Subagents, Plugins, and MCPs

https://arps18.github.io/posts/claude-code-mastery/
281•arps18•13h ago•203 comments

Corporations can vote in some Delaware elections, judge says

https://news.bloomberglaw.com/esg/corporations-have-the-right-to-vote-in-delaware-town-judge-says
82•marcher•3h ago•139 comments