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CRISPR tech selectively shreds cancer cells, including "undruggable" cancers

https://innovativegenomics.org/news/crispr-technique-selectively-shreds-cancer-cells/
484•gmays•5h ago•131 comments

I Am Not a Reverse Centaur

https://blog.miguelgrinberg.com/post/i-am-not-a-reverse-centaur
169•ibobev•2h ago•117 comments

Malware developers added nuclear and biological weapons text to to their spyware

https://twitter.com/jsrailton/status/2064661778978533571
183•marc__1•1d ago•111 comments

How to setup a local coding agent on macOS

https://ikyle.me/blog/2026/how-to-setup-a-local-coding-agent-on-macos
128•kkm•3h ago•44 comments

Pirates, a naval warfare game inspired by Sid Meier's Pirates

https://piwodlaiwo.github.io/pirates/
110•iweczek•3h ago•42 comments

Where Did Earth Get Its Oceans? Maybe It Made Them Itself

https://www.quantamagazine.org/where-did-earth-get-its-oceans-maybe-it-made-them-itself-20260612/
83•ibobev•5h ago•48 comments

Slightly reducing the sloppiness of AI generated front end

https://envs.net/~volpe/blog/posts/reduce-slop.html
133•FergusArgyll•5h ago•93 comments

Launch HN: BitBoard (YC P25) – Analytics Workspace for Agents

https://bitboard.work/
22•arcb•3h ago•9 comments

A PDF that changes based on how its read

https://sgaud.com/texts/pdf
88•SarthakGaud•4h ago•49 comments

A dumpster arrived behind my university's library

https://yalereview.org/article/sheila-liming-the-end-of-books
136•mooreds•6h ago•115 comments

AI agent bankrupted their operator while trying to scan DN42

https://lantian.pub/en/article/fun/ai-agent-bankrupted-their-operator-scan-dn42lantian.lantian/
1348•xiaoyu2006•16h ago•488 comments

Introduction to UEFI HTTP(s) Boot with QEMU/OVMF

https://blog.yadutaf.fr/2026/06/12/introduction-to-uefi-https-boot-qemu-ovmf/
49•jtlebigot•5h ago•14 comments

"Don't You Just Upload It to ChatGPT?"

https://correresmidestino.com/dont-you-just-upload-it-to-chatgpt/
147•speckx•2h ago•124 comments

There Is Life Before Main in Rust

https://grack.com/blog/2026/06/11/life-before-main/
46•mmastrac•1d ago•13 comments

Law Enforcement's "Warrior" Problem (2015)

https://harvardlawreview.org/forum/vol-128/law-enforcements-warrior-problem/
66•bookofjoe•3h ago•47 comments

Maxproof

https://arxiv.org/abs/2606.13473
118•ilreb•8h ago•10 comments

Cosmodial Sky Atlas

https://killedbyapixel.github.io/Cosmodial/
15•memalign•2h ago•1 comments

If you are asking for human attention, demonstrate human effort

https://tombedor.dev/human-attention-and-human-effort/
1419•jjfoooo4•21h ago•446 comments

Hazel (YC W24) Is Hiring a Full Stack Engineer

https://www.ycombinator.com/companies/hazel-2/jobs/3epPWgu-full-stack-engineer-ts-sci
1•augustschen•7h ago

Show HN: StackScope – I crawled over 40k indie launches to see what they ship

https://stackscope.dev/
32•datafreak_•5h ago•9 comments

WASI 0.3

https://bytecodealliance.org/articles/WASI-0.3
204•mavdol04•6h ago•82 comments

A Call to Action: Stop the FCC's KYC Regime

https://blog.lopp.net/call-to-action-stop-the-fcc-kyc-regime/
286•FergusArgyll•6h ago•189 comments

Looking Forward to Postgres 19: It's About Time

https://www.pgedge.com/blog/looking-forward-to-postgres-19-its-about-time
96•xngbuilds•3h ago•29 comments

Encrypted Spaces An architecture for collaborative applications

https://encryptedspaces.org/
50•_____k•8h ago•5 comments

New privacy frontier: Europe eyes crackdown on smart glasses

https://www.politico.com/www.politico.eu/article/new-privacy-frontier-europe-eyes-crackdown-smart...
70•1vuio0pswjnm7•4h ago•53 comments

A jacket that harvests drinking water from the air

https://news.utexas.edu/2026/06/11/this-jacket-pulls-drinking-water-from-thin-air/
152•ilreb•21h ago•96 comments

Kimi K2.7-Code: open-source coding model with better token efficiency

https://huggingface.co/moonshotai/Kimi-K2.7-Code
369•nekofneko•10h ago•197 comments

You can power on a Mac remotely

https://www.jeffgeerling.com/blog/2026/power-on-your-mac-remotely/
17•speckx•5h ago•5 comments

Nobody ever gets credit for fixing problems that never happened (2001) [pdf]

https://web.mit.edu/nelsonr/www/Repenning=Sterman_CMR_su01_.pdf
702•sam_bristow•20h ago•238 comments

Show HN: Script to bulk delete Claude chats from the web UI

https://github.com/MatteoLeonesi/bulk-delete-claude-chat
46•ML0037•5h ago•17 comments
Open in hackernews

A Peter Thiel-Backed Tribunal Is Putting Journalists on Trial

https://www.hollywoodreporter.com/business/business-news/peter-thiel-tribunal-journalists-trial-1236617579/
80•cdrnsf•2h ago

Comments

hsuduebc2•1h ago
Well, who could have possibly seen that coming right from this person. I'm so much waiting for this ridiculous AI psychosis driven grifters just to stop bothering other people with their bullshit.

>“It’s only the top 1 percent who matter. These are the people who are going to be the value creators” when, in his view, AI soon completely transforms just about every aspect of economic life.

>Among other criticisms, D’Souza dismisses the value of anonymous sources, believing they are discrediting, no matter the justification

k310•1h ago
Every supremacist accusation is a confession.

Remember, Thiel and Musk are both immigrants.

The U.S. legal system is very often a war of attrition. One side can relentlessly sue until the other side is broke, or just threaten. This is the basis of many plea deals, or worse, in the case of Aaron Swartz.

Billionaires seem to like it.

blfr•1h ago
Peter Thiel, who waged a legal war against Gawker Media after it published coverage about his business interests and personal life which upset him

This is being very economical with the facts.

Gawker outed Thiel as gay against his wishes. And while the guy was in Saudi Arabia. Then they published a revenge porn tape of Hulk Hogan, which is what Thiel used to get them.

seydor•1h ago
i remember knowing that thiel was gay before that story, and i m not even american. the sex tape was bad indeed.
caycep•1h ago
or....was that a convenient cover story?

https://medium.com/@owenthomas/gawker-peter-thiel-and-me-f80...

ToucanLoucan•1h ago
Gawker outing people against their wishes, the person they outed being one of the larger avatars of the crypto-fascist right, who worked with one of the biggest co-conspirators of Vince McMahon's brutal anti-union activities to destroy them for strictly personal reasons.

All of these people really deserve each other.

Edit: also for bonus points, him getting outed in such a dangerous place is ironic as all hell, given that he didn't need to be there apart from wanting money out of the Saudi royal family.

Like I wouldn't want to be outed while there either, but my answer is I wouldn't fucking go to Saudi Arabia with a gun to my head, and I certainly wouldn't be sucking up to the crown prince for m(b?)illions of dollars for my disinformation machine. But I guess principles are for the poors.

wat10000•56m ago
You wouldn't go there, and I wouldn't go there, but he's rich, there's no real risk for him.
pavlov•1h ago
Illiberal authoritarian monarchy is Thiel’s favorite form of government, so I’m not sure what his problem is with being outed while in Saudi Arabia.
seydor•1h ago
Didn't he move to that place where nazis went ?
some_furry•1h ago
Yeah, what's up with that? And how many VCs are considering following suit?
pesus•1h ago
Yup. After he's spent a considerable amount of time and money to promote Nazi politics.
dlahoda•59m ago
Ar is gay
drcongo•38m ago
Twitter?
Hikikomori•22m ago
Also grew up with spiritual Nazis.
bko•1h ago
> Peter Thiel, who waged a legal war against Gawker Media after it published coverage about his business interests and personal life which upset him.

Didn't Gawker publish an illegally obtained sex tape of Hogan and refused to take it down even after a court order?

giantfrog•1h ago
But on April 21, I received a remarkable email. “Someone has filed an objection against something you wrote,”

No one in their right mind is going to do anything other than ignore and/or delete an email this stupid.

doctorpangloss•59m ago
> We’re the first people to sell adjudication as a service

PolyMarket and Kalshi are sort of doing that, you could say, adjudication is a valuable service for gambling.

I've always thought that the chatbots were much better judges than lawyers. Some real US courts are adopting chatbots for clerical tasks. Hard to say if you can directly sell the services of judging in a general sense, seemingly the only way that is done is for gambling.

separately, @dang, is it possible to just cut out the vamping about anything at the top level that isn't really about what is being written

Jtsummers•53m ago
> separately, @dang, is it possible to just cut out the vamping about anything at the top level that isn't really about what is being written

@dang does nothing, email the mods if it's something you care about. Downvoting and flagging are the usual ways to deal with off-topic discussions, though the mods do occasionally create a "stub for off-topicness" and move comments under an auto-collapsed comment of theirs. Again, though, @dang won't reach him, email the mods.

devindotcom•51m ago
What a silly little venture. Essentially a vanity publication for rich fools with thin skin. Though very amusing how completely it fell apart at the slightest prodding by this reporter.

edit - kind of curious why this was flagged and removed?

Lerc•39m ago
Good people can do bad things.

Bad people can do good things.

Evaluate the things, you may do so being aware of their provenance, but if you use that as the starting point of your conclusion then you are just asking for your biases to be confirmed.

There does need to be a higher form of journalistic accountability. If Thiel, or any other person on the planet, proposed a fair mechanism that was free from influence, I would support it.

For this I don't neet to know who is behind it, I need to know what its goals are, how it operates, and how does it maintain integrity.

Certainly coming from an odius person increases the chance it will not measure up, but for fucks sake, at least do the measuring.

delichon•22m ago
> Due to feedback we’re rebuilding for an epistemic and primary sourced future. Stay tuned for updates.

Bravo. That's the way to approach this. Let thousands of such courts of public opinion bloom, with competing epistemic standards. We should definitely be experimenting with all different forms of truth seeking, and there's a great new toolbox to build them with, combined with infinite social forms.

I can't think of anything more valuable to humanity than making even modest progress on the process of separating fact from fiction. We should be cheerleading attempts, however goofy.

alexpotato•20m ago
For folks interested in how far a publisher will go for a journalist, I recommend reading the story about Michael Pollan when he wanted to publish an article about opium.

Summary:

- first publisher said: you can't publish this b/c you could go to prison and we could get in trouble financially

- second publisher: you are going to publish this. If you go to prison, we will support your family financially for the entire time you are in prison. If you lose your house, we will buy them a new house.

You can read about it here: https://tim.blog/2021/06/30/michael-pollan-this-is-your-mind...

People talk a LOT about defending free speech but this story has always stuck out to me as what that really means.

collingreen•48m ago
Thiel is firmly in the "rules for thee but not for me" camp which means any authoritarianism he isn't in control of is even worse than a democracy. Ironically many people feel this way but most just don't have the wealth to try their hand at oppression.
smegma2•45m ago
Is it your favorite form of government? If not, then why are you speaking in favor of it?
newaccountman2•44m ago
At what point did the person to whom you are replying speak in favor of it?
newaccountman2•54m ago
Your pointing out he was in Saudi Arabia is being very misleading with the facts.

It's not like Saudi Arabia cares whether some billionaire Western businessman is gay or not. They also don't care that he's a bigot and an Islamophobe, and he doesn't care that they are Arab, outwardly Muslim, or any other thing he detests. They all worship money.

randycupertino•53m ago
Yes Gawker was unethical and shouldn't have posted his personal details nor an illegally obtained sex tape, however billionaires shouldn't be able to destroy, censor and control media by deploying their unlimited resources to financially annihilate media outlets in endless litigation to take down reporting they don't like.

Free press is already under attack in so many countries, it is dangerous that now a single rich guy can weaponize his unlimited resources to wage legal war over his own personal vendettas because his ego got hurt.