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Artificial Intelligence: Ars Notoria and the Promise of Instant Knowledge

https://publicdomainreview.org/essay/ars-notoria/
6•jruohonen•32m ago•1 comments

Show HN: Syncular – offline-first SQL sync with TypeScript and Rust cores

https://github.com/syncular/syncular
10•quambo•1h ago•3 comments

Show HN: Bor – Open-source policy management for Linux desktops

https://getbor.dev/blog/2026-08-02-bor-v080-release/
12•eniac111•1h ago•0 comments

Go 1.27 Interactive Tour

https://victoriametrics.com/blog/go-1-27/index.html
230•Hixon10•9h ago•88 comments

Is the Industrial Revolution a good precedent for explosive growth today?

https://mattsclancy.github.io/2026/07/27/industrial-revolution-growth.html
4•NewCzech•25m ago•0 comments

Show HN: I'm a 15 Year Old Wannabe Engineer, This Is a Cycloidal Gearbox I Built

https://github.com/tom-ilan/cycloidal_gearbox
175•tomilan•8h ago•45 comments

Seedance 2.5

https://seed.bytedance.com/en/blog/one-take-creation-flexible-referencing-introducing-seedance-2-5
354•njaremko•14h ago•186 comments

A big win for Android interoperability

https://www.openhomefoundation.org/blog/a-big-win-for-android-interoperability/
120•soheilpro•1d ago•38 comments

MkLinux and the pimped-out Apple Workgroup Server 9150

http://oldvcr.blogspot.com/2026/08/mklinux-and-pimped-out-apple-workgroup.html
59•goldenskye•7h ago•3 comments

Diátaxis

https://diataxis.fr/
367•ryanseys•14h ago•46 comments

Police in the US are making their own true crime podcasts

https://www.bbc.com/news/articles/cpw9q0ekd9eo
11•1659447091•3h ago•8 comments

Maze Toys

https://maze.toys
6•bookofjoe•1d ago•0 comments

I don't recommend Tailwind CSS

https://en.andros.dev/blog/af3ee191/why-i-dont-recommend-tailwind-css/
98•andros•3h ago•95 comments

Deep-sea vehicles spot 'alien' sharks deep beneath the waves in the Pacific

https://www.science.org/content/article/deep-sea-vehicles-spot-alien-sharks-deep-beneath-waves-pa...
56•pkaeding•7h ago•22 comments

ASRock BC-250: Building the Budget Steam Machine

https://plug-world.com/posts/2026/asrock-bc250-the-budget-steam-machine/
68•plug_world•9h ago•27 comments

Running Kimi K3 on MI355X at Better Performance per Dollar Than B300

https://www.wafer.ai/blog/kimi-k3-mi355x
132•ilreb•6h ago•44 comments

Cyberscript

https://cyberscript.dev
7•dtj1123•2h ago•1 comments

Morph (YC S23) Is Hiring Member of Technical Staff

https://www.ycombinator.com/companies/morph/jobs/0Z8vI3K-member-of-technical-staff
1•bhaktatejas922•11h ago

When random.bytes() runs but doesn't work

https://insider.btcpp.dev/p/when-randombytes-runs-but-doesnt
51•Funes-•8h ago•22 comments

Show HN: Logan Basic v2.1 - An online BASIC interpreter.

https://sinusoft.com/loganbasic/
10•Sinusoid314•2d ago•3 comments

Elena, a library for building Progressive Web Components

https://elenajs.com/
35•brianzelip•2d ago•2 comments

Postmortem for Kernel Soundness Bug #14576

https://leodemoura.github.io/blog/2026-8-1-postmortem-for-kernel-soundness-bug-14576/
150•juhopitk•16h ago•57 comments

Unraveling the mysteries of habit formation

https://www.kyoto-u.ac.jp/en/research-news/2026-07-28
81•hhs•11h ago•30 comments

IBM i (OS/400) the Database Operating System

https://osadmins.com/en/ibm-i-os-400-the-database-operating-system/
7•naves•3h ago•0 comments

The time filter in Google Search broke a few days ago

https://mastodon.online/@mwichary/117023736804129342
19•latexr•2h ago•8 comments

RFC 10015: Deprecating Obsolete Key Exchange Methods in TLS 1.2 and DTLS 1.2

https://www.rfc-editor.org/rfc/rfc10015.html
60•Jimmc414•11h ago•15 comments

But can your calculator run Linux?

https://raymii.org/s/articles/But_can_your_calculator_run_Linux.html
97•jandeboevrie•15h ago•9 comments

Instrumenting my espresso machine with OpenTelemetry

https://clickhouse.com/blog/espresso-machine-observability-with-otel
12•g0xA52A2A•3d ago•2 comments

The Prospects for 128 Bit Processors ( John Mashey SGI 1995)

https://yarchive.net/comp/128bit.html
24•Alien1Being•9h ago•8 comments

Mathematics Without Mathematicians

https://borretti.me/article/mathematics-without-mathematicians
12•varjag•3h ago•6 comments
Open in hackernews

Drug reverses autism-like brain changes in adult mice within hours

https://www.uclahealth.org/news/release/drug-reverses-autism-like-brain-changes-adult-mice-within
31•gmays•12h ago

Comments

galleywest200•8h ago
> The effects of rapamycin are temporary, and repeated dosing loses efficacy, making rapamycin, itself, an unlikely candidate as a broadly-used treatment.
onesandofgrain•2h ago
Cycling is possible
SoMomentary•1h ago
Doesn't the "potential for toxicity from repeated doses" make this sort of doubtful?
RobotToaster•36m ago
Possibly, possibly not.

Bryan Johnson took it for 5 years in an attempt to slow aging. He eventually discontinued because it was causing an increase in skin infections (as you'd expect from an immune system suppressant), but cycling could mitigate that.

ButlerianJihad•8h ago
https://en.wikipedia.org/wiki/Flowers_for_Algernon
sublinear•6h ago
More like

https://en.wikipedia.org/wiki/Madness_and_Civilization

Scandiravian•2h ago
Being autistic myself, I feel conflicted about trying to "cure autism"

Every day is challenging because I have to manage my energy, mask in social situations and at work, etc

On the other hand, I like who I am and I'm also very good at what I do because my brain is structured the way it is. I can imagine a society that is structured in a way, where I don't need the accommodations I'm currently dependent on

If the negative impacts I'm experiencing are a consequence of the how we've structured our society, then I don't think it's autistic people who need to change to fit in

Of course there are much more severe cases than me where autistic people need much more support and have severe learning disabilities, where it could be a huge improvement to quality of life

If it was possible to fully trust that a hypothetical "cure" would only be used in these severe cases, I might be excited about a potential breakthrough, but historically this unfortunately haven't been the case

f6v•50m ago
> If it was possible to fully trust that a hypothetical "cure" would only be used in these severe cases

Isn’t it like the Ozempic? Some take it, some don’t.

applfanboysbgon•42m ago
They have a valid concern. Unlike obesity, people with anything regarded as an intellectual disability are liable to have other people attempting to make decisions on their behalf, denying them agency over their own treatment, and legal systems will often enforce this denial of agency.
dns_snek•35m ago
I see this sentiment often, but only when it comes to autism. How is this different from other disorders, disabilities, illnesses?

You could make the exact same arguments for blindness. Every day is challenging, difficulties are mostly a consequence of how we've structured society, it's other people who should accommodate those who have different needs, etc.

This narrative seems to originate from, and is perpetuated within online autism communities. I think it's great that people feel content with the way they are but I don't understand the animosity towards a mere suggestion that a cure should exist.

I'm familiar with the history behind it and I'm on high alert when someone ventures into eugenics, however I firmly believe that we should be looking for a cure, just like we do for every other illness and disorder.

LoganDark•2h ago
This is interesting, it may be a type of thing I'd be curious about at some point. I don't think it's possible to undo the general way my brain is organized (badly), but I'd be curious to see if I'd get any benefit anyway.

(I seem to be a rare type of autistic, because while I can reliably find all three other major types, it has been very difficult for me to find more of my own :/)

metalman•21m ago
so, like a vacine against autism, rather than the impossibility of it bieng caused by one? instantly?
jimnotgym•10m ago
Because many autistic people have superpowers in some areas, like systems thinking, thinking outside the box and maybe suprisingly reading people.

If you had a superpower, but it came with a curse, that you couldn't always get to work on time, would you trade it in for a normal life?

On the other hand, i don't see why a company wouldn't accommodate someone's minor quirks to get access to a superpower.

ssl-3•6m ago
> I see this sentiment often, but only when it comes to autism. How is this different from other disorders, disabilities, illnesses?

These are not equivalent, synonymous terms. I think that your premise might need some work.

There's plenty of people in the world who are healthy, autistic, and not disabled at all.

saidnooneever•28m ago
i liken it to ADHD medicine. if you give it early in life then people often end up using it and benefitting from it. Later life diagnoses see people not take the medicine because their condition has become their person and changing that feels like it changes them too much from themselves.

Ultimately its all about being able to manage your life. If you run into troubles due to some condition it can cause to want a drug for it, but if you can manage often it can feels wrong to take it.

dns_snek•17m ago
> Later life diagnoses see people not take the medicine because their condition has become their person and changing that feels like it changes them too much from themselves.

I also see this sentiment frequently but as someone who was diagnosed later in life I couldn't relate to it less. The scattered brain has lead me down some interesting (and fruitful) paths I wouldn't have explored otherwise, but 95% of the time it just distracts me from goals that are actually meaningful to me in the long term, and adds social friction and conflict.

I'd like to see someone study why there's such a stark difference in how people perceive it. Stimulant medication, good sleep, physical activity all help somewhat but they just take it down a notch. There are some aspects where they help a lot and others where they barely make a difference.