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A Backtest for Scientific Insight

https://willmichaels.substack.com/p/a-backtest-for-scientific-insight
4•wmichaels•1h ago

Comments

andsoitis•1h ago
> In my view, the resolution of this thought experiment would shed light on many of the claims being made about the ability for AI to accelerate science. Recently, there have been multiple claims of AI systems making scientific discoveries or proving theorems. It is usually difficult to assess whether these are incremental or significant, and the degree to which an AI generated the insight

Specialization and abundance of information have created siloing, less interdisciplinary work. To make breakthroughs in physics, you have to spend the better part of your life studying things like string theory or quantum field theory, and then you still don't know anything about other fields.

Scientific insights, I bet, will come from AI sifting through the data as well as the knowledge and make novel connections that any one human or even a group of humans would struggle to make, if make at all. I can imagine how humans can then build on these new insightful connection to make further leaps that AI can then build off of again.

One thing that puts a limit on the pace of scientific progress is the verification and experimentation parts. While AI can theoretically make discoveries authonomously in fields like mathematics, for physics, biology, medicine, and many other fields, you need to interact with the physical world (experiments, trials), so the breakthrough loop can't accelerate "infinitely".

Robotics can address some of that, but there will remain physical limits, I anticipate.

Site is now webmention-aware

https://kevinboone.me/webmention.html
1•thomasjb•13s ago•0 comments

As memory shortage persists, vendor price quotes are not long remembered

https://www.theregister.com/2026/02/18/memory_shortage_persists_vendor_change_terms/
1•geekinchief•37s ago•0 comments

The 80% Power Lie

https://statmodeling.stat.columbia.edu/2026/02/19/the-80-power-lie/
1•Tomte•48s ago•0 comments

Learning KeyBee

https://entropicthoughts.com/learning-keybee
1•surprisetalk•1m ago•0 comments

Keybee: A Keyboard Designed for Smartphones

https://keybeekeyboard.com/
1•surprisetalk•1m ago•0 comments

Untapped Way to Learn a Codebase: Build a Visualizer

https://jimmyhmiller.com/learn-codebase-visualizer
1•surprisetalk•1m ago•0 comments

Cringeworthy in the Future

https://kevinkelly.substack.com/p/cringeworthy-in-the-future
1•surprisetalk•1m ago•0 comments

Testing Linux memory limits is a bit of a pain

https://utcc.utoronto.ca/~cks/space/blog/linux/MemoryLimitTestingPain
1•speckx•2m ago•0 comments

Accenture 'links staff promotions to use of AI tools'

https://www.theguardian.com/accenture/2026/feb/19/accenture-links-staff-promotions-to-use-of-ai-t...
1•akyuu•2m ago•0 comments

NSA and IETF, Part 5

https://blog.cr.yp.to/20260219-obaa.html
1•Tomte•2m ago•0 comments

International box-sizing Awareness Day

https://css-tricks.com/international-box-sizing-awareness-day/
1•hisamafahri•4m ago•0 comments

You Are NOT getting replaced [video]

https://www.youtube.com/watch?v=DjMrPqwLaiw
1•znpy•4m ago•0 comments

Show HN: AI agent audited its platform, got 80% wrong, rewrote its methodology

https://openseed.dev/blog/escape-hatch/
1•rsdza•4m ago•2 comments

Astronomers detect a solar system they say should not be possible

https://www.cnn.com/2026/02/12/science/solar-system-inside-out-planets
1•Brajeshwar•5m ago•0 comments

Show HN: Oura Ring 4, Thoughts?

https://kirkstechtips.com/oura-ring-4-review-the-smart-ring-finally-worth-the-hype/
2•daveshappy•5m ago•1 comments

Baby microbiomes in the West differ from those everywhere else

https://www.newscientist.com/article/2516131-how-baby-microbiomes-in-the-west-differ-from-those-e...
1•Brajeshwar•6m ago•0 comments

Taste for Makers (2002)

https://paulgraham.com/taste.html
1•Brajeshwar•6m ago•0 comments

Host Leadership

https://martinfowler.com/bliki/HostLeadership.html
1•donutshop•6m ago•0 comments

Show HN: CMV – Virtual memory for Claude Code sessions

https://github.com/CosmoNaught/claude-code-cmv
1•CosmoSantoni•7m ago•0 comments

Show HN: HyprVim – System-wide Vim-like modes in Hyprland (with which-key HUD)

https://github.com/uhs-robert/hyprvim
1•uhs-robert•10m ago•1 comments

US admin official threatens NY Fed economists – Krugman [video]

https://www.youtube.com/watch?v=lzZdxmSmBaM
2•burnt-resistor•11m ago•0 comments

Google Banning AI Ultra subscribers for using OpenCode while still charging them

https://old.reddit.com/r/google_antigravity/comments/1r2hnn8/ultra_user_get_banned/
3•smashah•12m ago•0 comments

Meta CEO Knew Kids Were Being Hurt and He Covered It Up

https://dispatch.techoversight.org/email/23724686-b700-489a-9677-327799e75e5e/
4•speckx•12m ago•0 comments

56% of PyPI malware runs at install, so I sandboxed pip with eBPF

10•otsmane_ahmed•14m ago•0 comments

Show HN: HoldMyWhoop – Professional wearable delegation for fitness trackers

https://holdmywhoop.com
2•iaro-dev•18m ago•0 comments

Baboon Raiders: In Cape Town, Can Big Primates and People Coexist?

https://e360.yale.edu/features/cape-town-baboons
1•YaleE360•19m ago•0 comments

Humanity Has Managed to Fall into Time Loop Regarding "AI"

1•kokhanserhii•19m ago•4 comments

UK: Tech firms will have to take down NCII within 48 hours

https://www.gov.uk/government/news/tech-firms-will-have-to-take-down-abusive-images-within-48-hou...
1•pjc50•20m ago•0 comments

Show HN: Credit-to-currency conversion controls for wallet-based billing

http://Link:admin.flexprice.io
3•ShreyaChaurasia•20m ago•2 comments

Show HN: The Lamplighter – Same story from left, right, and verified center

https://thelamplighter.ink
2•Sleeves•20m ago•0 comments