frontpage.
newsnewestaskshowjobs

Made with ♥ by @iamnishanth

Open Source @Github

fp.

Open in hackernews

Early adult drinking linked to middleage cognitive decline–even after abstinence

https://medicalxpress.com/news/2026-03-early-adult-linked-middle-age.html
10•OutOfHere•3h ago

Comments

Gigachad•2h ago
In mice. The original paper has this in the title but the article version has stripped it.

Not to say this is useless research, but I was interested to see the ages and quantity involved. Surprised to see none of that was mentioned in the article. Feels like this article is giving false anxiety to people.

OutOfHere•1h ago
The article is a warning to those who drink alcohol, especially if it's to cope. The point is that drinking it then risks cognitive decline. This risk is best avoided by stopping drinking altogether. Yes, the study is in mice, but it still conveys an applicable risk to humans.

In my experience, a lot of the need to cope is actually due to dirty indoor air. Aggressively using air filtration+ventilation to significantly drive down indoor pollution goes a long way. As for outdoor air, if exposed to significant outdoor pollution, masks help.

Gigachad•1h ago
The article version is overly alarmist in a way the source material isn't. We know alcohol is bad for you, what would be useful to know is what quantities, at what ages, translating in to what increase in risk.

This just feels like telling someone if they had any amount of alcohol at "early adulthood" they have brain damage and there is nothing they can do about it.

strongpigeon•2h ago
Title is fairly misleading. This is about mice who use alcohol as a stress coping mechanism, not about drinking in general.
JamesTRexx•2h ago
That was the whole point of me drinking in the evening, to decline my cognitivity of the idiotic world I had to deal with during the day.

Unfortunately it doesn't work as well nowadays while the world became more idiotic.

sublinear•47m ago
I have no qualifications other than approaching middle age and formerly being a heavy drinker between the ages of 25 and 35.

> After a history of stress and drinking, the brain simply works differently

I agree with this. You can generally tell who is/was a drinker by their personality.

> one's ability to think on one's feet and adapt to new and challenging situations—is markedly reduced

I disagree and believe the exact opposite is usually true. I have observed so many alcoholics seem to be on a different level of insight and experience than everyone else. It's as if the stress of trying to stay composed while being drunk all the time brings its own adaptive behaviors and introspection.

I'm not saying alcoholism is a good thing, but you have to give credit where it's due. The smoothest talkers and most likely to pull a plan out of their ass that actually works are/were all drunks. That's not luck. That's a lot of hard won knowledge.

TypeScript's rise in the AI era: Insights from Anders Hejlsberg (2025)

https://github.blog/developer-skills/programming-languages-and-frameworks/typescripts-rise-in-the...
1•pramodbiligiri•2m ago•0 comments

Donut Lab Battery Test 4 Changes Everything [video]

https://www.youtube.com/watch?v=5cpYeT4VmSY
1•fencedload•3m ago•0 comments

NYC Once Banned Free Legal Advice over Radio

https://newsletter.pessimistsarchive.org/p/nyc-once-banned-free-legal-advice
1•walterbell•6m ago•0 comments

True 4-Bit Quantized CNN Training on CPU – 92.34% on Cifar-10

https://arxiv.org/abs/2603.13931
1•shivnathtathe•10m ago•0 comments

My Willing Complicity in "Human Rights Abuse"

https://ussri.substack.com/p/my-willing-complicity-in-human-rights
1•oxw•13m ago•0 comments

Ask HN: When do you start considering to 'separate' service designed with DDD

1•Lazy_Player82•18m ago•0 comments

Public Access Databases

https://robertsdotpm.github.io/software_engineering/public_databases.html
2•Uptrenda•19m ago•0 comments

You train robots and don't even know it

https://twitter.com/k1rallik/status/2033530122150502482
1•dsr12•21m ago•0 comments

Show HN: MCP Inspector – connect and test any MCP server

https://glama.ai/mcp/inspector
1•punkpeye•28m ago•0 comments

Kagi Translate now supports LinkedIn Speak as an output language

https://translate.kagi.com/?from=en&to=LinkedIn+speak
28•smitec•33m ago•5 comments

J Epstein Perma Twitter

1•benjaminklick•35m ago•1 comments

Threading Async Together

https://github.com/TavariAgent/Py-TokenGate
2•Tavari•36m ago•1 comments

Ask HN: People reverse engineering web apps, what are you doing it for?

3•keepamovin•40m ago•0 comments

Can You Brute Force the NYT Connections with Math? [video]

https://www.youtube.com/watch?v=POGGNamZoHQ
2•Timothee•40m ago•0 comments

RetroAgent: From Solving to Evolving via Retrospective Dual Intrinsic Feedback

https://github.com/zhangxy-2019/RetroAgent
1•frozenseven•45m ago•1 comments

New Nvidia DLSS Tech Gives Characters AI Slop Faces

https://kotaku.com/new-nvidia-dlss-tech-gives-characters-ai-slop-faces-2000679199
1•mikhael•47m ago•0 comments

human.json

https://evanhahn.com/human-dot-json/
3•nikolay•49m ago•1 comments

Nvidia DLSS 5 – AI-Powered Breakthrough in Visual Fidelity for Games [video]

https://www.youtube.com/watch?v=dJACkKbN-Eo
3•qingcharles•50m ago•0 comments

Show HN: Free library of 2k martial arts books – read in the browser

https://fightencyclopedia.com/library
2•acenji•54m ago•0 comments

The Power of Playtesting in the Classroom

https://landenlove.com/the-power-of-playtesting-in-the-classroom/
2•LandenLove•56m ago•2 comments

Drafting Earnout Agreements to Minimize Disputes After Sale of Private Companies

https://natlawreview.com/article/earnout-burnout-drafting-earnout-agreements-minimize-disputes-fo...
2•petethomas•1h ago•0 comments

Zenclora OS

https://zenclora.org/
17•debo_•1h ago•10 comments

SEC Prepares Proposal to Eliminate Quarterly Reporting Requirement

https://www.wsj.com/finance/regulation/sec-prepares-proposal-to-eliminate-quarterly-reporting-req...
5•jonbaer•1h ago•0 comments

The third agent is me [video]

https://www.youtube.com/watch?v=HbWu_eYIHKQ
1•BeenSolo•1h ago•0 comments

Monkey Island for Commodore 64 Ground Up

https://pixeldust.se/monkey-island-project
34•aresant•1h ago•5 comments

Reverse engineering a no-name Chinese smartwatch BLE protocol (Jieli chipset)

https://github.com/TruthGh0st/C30-20-Pro-BLE-Reverse-Engineering
2•Truth_Gh0st•1h ago•1 comments

French Bees Are Making M&M-Contaminated Blue and Green Honey (2012)

https://www.smithsonianmag.com/smart-news/french-bees-are-making-mm-contaminated-blue-and-green-h...
4•thunderbong•1h ago•0 comments

The Billionaire Backlash Against a Philanthropic Dream

https://www.nytimes.com/2026/03/15/business/the-billionaire-backlash-against-a-philanthropic-drea...
1•627467•1h ago•0 comments

Boot ROM Security on Silicon Macs (M1/M2/M3)

https://oliviagallucci.com/boot-rom-security-on-silicon-macs-m1-m2-m3/
2•0xkato•1h ago•0 comments

The Building Blocks of Agentic AI

https://ai.meta.com/blog/introducing-pytorch-native-agentic-stack/?_fb_noscript=1
1•werinly•1h ago•0 comments